Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Volker Korz"'
Autor:
Heike Mrowetz, Mohamed H. Kotob, Jennifer Forster, Iren Aydin, Michael Stefan Unger, Jana Lubec, Ahmed M. Hussein, Jovana Malikovic, Daniel Daba Feyissa, Volker Korz, Harald Höger, Gert Lubec, Ludwig Aigner
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionAging is in general associated with a decline in cognitive functions. Looking more closely, there is a huge heterogeneity in the extent of cognitive (dys-)abilities in the aged population. It ranges from the population of resistant, resil
Externí odkaz:
https://doaj.org/article/c72b85bed7694a5d966164b55ce82d17
Autor:
Jana Lubec, Ahmed M. Hussein, Predrag Kalaba, Daniel Daba Feyissa, Edgar Arias-Sandoval, Anita Cybulska-Klosowicz, Mekite Bezu, Tamara Stojanovic, Volker Korz, Jovana Malikovic, Nilima Y. Aher, Martin Zehl, Vladimir Dragacevic, Johann Jakob Leban, Claudia Sagheddu, Judith Wackerlig, Marco Pistis, Merce Correa, Thierry Langer, Ernst Urban, Harald Höger, Gert Lubec
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 467 (2023)
The worldwide increase in cognitive decline, both in aging and with psychiatric disorders, warrants a search for pharmacological treatment. Although dopaminergic treatment approaches represent a major step forward, current dopamine transporter (DAT)
Externí odkaz:
https://doaj.org/article/31e9c20c5680455db70326abd3c16764
Autor:
Artem Savchenko, Carina Müller, Jana Lubec, Damiana Leo, Volker Korz, Leila Afjehi-Sadat, Jovana Malikovic, Fernando J. Sialana, Gert Lubec, Ilya Sukhanov
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Dopamine (DA) is critically involved in different functions of the central nervous system (CNS) including control of voluntary movement, affect, reward, sleep, and cognition. One of the key components of DA neurotransmission is DA reuptake by the DA
Externí odkaz:
https://doaj.org/article/0efc09e823854a73b25219113ef3eb7e
Autor:
Jovana Maliković, Daniel Daba Feyissa, Predrag Kalaba, Babak Saber Marouf, Harald Höger, Michaela F. Hartmann, Stefan A. Wudy, Gerhard Schuler, Gert Lubec, Jana Aradska, Volker Korz
Publikováno v:
Behavioral and Brain Functions, Vol 15, Iss 1, Pp 1-10 (2019)
Abstract Background Age-dependent alterations of hormonal states have been considered to be involved in age related decline of cognitive abilities. Most of the studies in animal models are based on hormonal substitution in adrenal- and/or gonadectomi
Externí odkaz:
https://doaj.org/article/ead45dc2907c4e7b9a336d12861e5205
Autor:
Volker Korz, Christopher Kremslehner, Jovana Maliković, Ahmed Hussein, Daniel Daba Feyissa, Ionela-Mariana Nagelreiter, Roman Smidak, Roberto Plasenzotti, Florian Gruber, Gert Lubec
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2021)
Cognitive processes require striatal activity. The underlying molecular mechanisms are widely unknown. For this reason the striatal transcriptome of young (YM), aged cognitively impaired (OMB), and unimpaired (OMG) male rats was analyzed. The global
Externí odkaz:
https://doaj.org/article/eb35792eb8fd4ad78be86ac41d48ccd1
Autor:
Judith Wackerlig, Harald C. Köfeler, Volker Korz, Ahmed M. Hussein, Daniel D. Feyissa, Harald Höger, Ernst Urban, Thierry Langer, Gert Lubec, Jana Lubec
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Lipids play a major role for several brain functions, including cognition and memory. There is a series of work on individual lipids showing involvement in memory mechanisms, a concise lipidome was not reported so far. Moreover, there is no evidence
Externí odkaz:
https://doaj.org/article/8ca204f0b91048ea9dedfa9d37913337
Autor:
Jana Lubec, Roman Smidak, Jovana Malikovic, Daniel Daba Feyissa, Volker Korz, Harald Höger, Gert Lubec
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Similar to humans, the normal aged rat population is not homogeneous in terms of cognitive function. Two distinct subpopulations of aged Sprague–Dawley rats can be identified on the basis of spatial memory performance in the hole-board paradigm. It
Externí odkaz:
https://doaj.org/article/726b33dd5cd24296bb20f638dbb59f60
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Nutrition can have significant effects on behavior and cognitive processes. Most of the studies related to this use extremely modified diets, such as high fat contents or the exclusion of distinct components needed for normal development and bodily h
Externí odkaz:
https://doaj.org/article/c7d1e22b604d4418947128c632b0a055
Publikováno v:
Bio-Protocol, Vol 8, Iss 14 (2018)
Working memory is short-term memory, so temporal improvement does not reflect the consolidation of a memory trace, rather the functionality of the underlying neuronal circuits and molecular signaling cascades. The administration of drugs–either one
Externí odkaz:
https://doaj.org/article/85f73a6fa66740a5bfb5d1d0c10affd7
Autor:
Agnieszka Nikiforuk, Predrag Kalaba, Marija Ilic, Volker Korz, Vladimir Dragačević, Judith Wackerlig, Thierry Langer, Harald Höger, Joanna Golebiowska, Piotr Popik, Gert Lubec
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
Reduced cognitive abilities are often characterized by an impairment of flexibility, i.e., the ability to switch from learned rules or categories that were important in certain contexts to different new modalities that rule the task. Drugs targeting
Externí odkaz:
https://doaj.org/article/8a6fb1a9aa7041c1b1baf84bc3560418