Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Volker Germaschewski"'
Autor:
Nadine D. Arnold, Josephine A. Pickworth, Laura E. West, Sarah Dawson, Joana A. Carvalho, Helen Casbolt, Adam T. Braithwaite, James Iremonger, Lewis Renshall, Volker Germaschewski, Matthew McCourt, Philip Bland-Ward, Hager Kowash, Abdul G. Hameed, Alexander M. K. Rothman, Maria G. Frid, A. A. Roger Thompson, Holly R. Evans, Mark Southwood, Nicholas W. Morrell, David C. Crossman, Moira K. B. Whyte, Kurt R. Stenmark, Christopher M. Newman, David G. Kiely, Sheila E. Francis, Allan Lawrie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Pulmonary arterial hypertension (PAH) is characterised by progressive pulmonary vascular remodelling. Here, Arnold et al. develop a therapeutic antibody targeting osteoprotegerin and find it attenuates pulmonary vascular remodelling in multiple roden
Externí odkaz:
https://doaj.org/article/fbbe9cf6fb44471db21ebf04ce2094b6
Autor:
Ian Catchpole, Volker Germaschewski, Jaimie Hoh Kam, Peter Lundh von Leithner, Susannah Ford, Gerald Gough, Peter Adamson, Philip Overend, Jan Hilpert, Francisco J López, Yin Shan Eric Ng, Pete Coffey, Glen Jeffery
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65518 (2013)
Age-related macular degeneration (AMD) is a leading cause of legal blindness in the Western world. There are effective treatments for the vascular complications of neo-vascular AMD, but no effective therapies are available for the dry/atrophic form o
Externí odkaz:
https://doaj.org/article/6539fac7475647f0915a94c21e3d40a3
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
AntilCOS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba1f887a0a35c8e986e2343266bfd90
https://doi.org/10.1158/2326-6066.22543483.v1
https://doi.org/10.1158/2326-6066.22543483.v1
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
Supplementary Figures 1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e902185bdfb8b67303be2284d9cf03dc
https://doi.org/10.1158/2326-6066.22543489.v1
https://doi.org/10.1158/2326-6066.22543489.v1
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
Metadata for the 5 NSCLC patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1800b3397d3acb7f2682b1bdbfbacca6
https://doi.org/10.1158/2326-6066.22543474.v1
https://doi.org/10.1158/2326-6066.22543474.v1
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
Isotype control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4666fafa648372d124a70fb2d8120a28
https://doi.org/10.1158/2326-6066.22543480
https://doi.org/10.1158/2326-6066.22543480
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
Figure and tables legends of supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e724c6e6d036f84baa17890e6f1a08a
https://doi.org/10.1158/2326-6066.22543492
https://doi.org/10.1158/2326-6066.22543492
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
The immunosuppressive tumor microenvironment constitutes a significant hurdle to immune checkpoint inhibitor responses. Both soluble factors and specialized immune cells, such as regulatory T cells (Treg), are key components of active intratumoral im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b3a5625eeaea7fd185b7366ab732c
https://doi.org/10.1158/2326-6066.c.6550282
https://doi.org/10.1158/2326-6066.c.6550282
Autor:
Matthew McCourt, Sonia Quaratino, Elisabeth Oelmann, Volker Germaschewski, David Melvin, Ian Kirby, Jamie Campbell, Morgane Lecointre, Robert J. Rowlands, Qi Liang, Vivian W.Y. Wong, Hannah Craig, Hanif Ali, Eleanor J. Pring, Emma Taggart, Lauriane Gamand, Cassie Van Krinks, Stuart Ball, Siobhan O'Leary, Tracey Okell, Kerstin L. Pryke, Simon J. Henderson, Joana Carvalho, Rachael Kimber, Nahida Parveen, Gwenoline Borhis, Miha Kosmac, Anil K. Thotakura, Richard C.A. Sainson
Genes used to define Immune cell subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2e881e349e2a4082e5fe260954d2f0
https://doi.org/10.1158/2326-6066.22543477
https://doi.org/10.1158/2326-6066.22543477
Autor:
Bertie Chi, Cynthia Clemente Gonzalez, Christopher A. Sellick, Louise Knightley, Geoffrey De Oliveira, Claire Pearce, Shannon Russell, Volker Germaschewski, Thomas Gallagher, Laura Mitchell
Publikováno v:
Biotechnology and Bioengineering. 118:3733-3743
As the number of antibody drugs being approved and marketed increases, our knowledge of what makes potential drug candidates a successful product has increased tremendously. One of the critical parameters that has become clear in the field is the imp