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pro vyhledávání: '"Volker Dangel"'
Autor:
Johannes Härle, Bertolt Gust, Lutz Heide, Christiane Wolz, Jean-Luc Pernodet, Christiane Goerke, Volker Dangel
Publikováno v:
Microbiology
Microbiology, Microbiology Society, 2009, 155 (Pt 12), pp.4025-35. ⟨10.1099/mic.0.032649-0⟩
Microbiology, Microbiology Society, 2009, 155 (Pt 12), pp.4025-35. ⟨10.1099/mic.0.032649-0⟩
The aminocoumarin antibiotic novobiocin is a gyrase inhibitor formed by a Streptomyces strain. The biosynthetic gene cluster of novobiocin spans 23.4 kb and contains 20 coding sequences, among them the two regulatory genes novE and novG. We investiga
Publikováno v:
Archives of Microbiology. 190:509-519
The biosynthetic gene cluster of the aminocoumarin antibiotic novobiocin contains two putative regulatory genes, i.e., novE and novG. Functional proof for the role of NovG as a positive regulator of novobiocin biosynthesis had been provided previousl
Publikováno v:
Journal of Clinical Virology. 35:303-309
Background Human cytomegalovirus (CMV) is the most common cause of viral intrauterine infection. Primary CMV infection in early pregnancy bears a high risk of fetal damage. Accurate measurement of CMV-specific IgG avidity may help to improve the sero
Publikováno v:
Applied microbiology and biotechnology. 87(1)
The biosynthetic gene cluster of the aminocoumarin antibiotic novobiocin comprises 20 coding sequences. Sixteen of them code for essential enzymes for novobiocin formation, transcribed in the form of a single 18-kb polycistronic mRNA. In the present
Publikováno v:
The Biochemical journal. 317
The regulation of the expression of beta-adrenoceptor (beta-ARs) is not thoroughly understood. We demonstrate that the rat heart cell-line H9c2 expresses both beta 1- and beta 2-ARs. In radioligand-binding experiments, the maximal binding capacity of