Výsledky vyhledávání - "Volker, Derdau"

Akademický článek

Molecular basis for inhibiting human glucose transporters by exofacial inhibitors

Autor: Nan Wang, Shuo Zhang, Yafei Yuan, Hanwen Xu, Elisabeth Defossa, Hans Matter, Melissa Besenius, Volker Derdau, Matthias Dreyer, Nis Halland, Kaihui Hu He, Stefan Petry, Michael Podeschwa, Norbert Tennagels, Xin Jiang, Nieng Yan

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Human glucose transporters (GLUTs), particularly GLUT1 and GLUT3, are potential anticancer therapy targets. Here, Nan Wang et al. use an engineered GLUT 3 variant to identify an exofacial GLUT3 inhibitor, SA47, and elucidate the drug’s inhibitory m

Externí odkaz: https://doaj.org/article/838595b279b94ca5b2244bbb0e9ea054

Zobrazit plný text záznamu

Akademický článek

Comparison of Iridium(I) Catalysts in Temperature Mediated Hydrogen Isotope Exchange Reactions

Autor: Mégane Valero, Dr. Anurag Mishra, Jennifer Blass, Remo Weck, Dr. Volker Derdau

Publikováno v: ChemistryOpen, Vol 8, Iss 9, Pp 1183-1189 (2019)

Abstract The reactivity and selectivity of iridium(I) catalysed hydrogen isotope exchange (HIE) reactions can be varied by using wide range of reaction temperatures. Herein, we have done a detailed comparison study with common iridium(I) catalysts (1

Externí odkaz: https://doaj.org/article/fd45a41c3a814e2fa5d3bd8e67631e5d

Zobrazit plný text záznamu

Plný text ve formátu HTML

Site-Selective C–H Functionalization of N-Aryl and N-Heteroaryl Piperidines, Morpholines, and Piperazines Controlled by a Chiral Dirhodium Tetracarboxylate Catalyst

Autor: Korkit Korvorapun, Yannick T. Boni, Thomas C. Maier, Armin Bauer, Thomas Licher, John E. Macor, Volker Derdau, Huw M. L. Davies

Publikováno v: ACS Catalysis. 13:2359-2366

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d19c8c319345a20484b831a435e7f99
https://doi.org/10.1021/acscatal.2c05283

Zobrazit plný text záznamu

Synthesis and analysis of isotopically stable labeled nitrosamines as mass spectrometry standards for drug impurity quality control

Autor: Volker Derdau, Martin Sandvoss

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 66:41-46

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74f99a263688c3bb615dd9ed4b60b4e5
https://doi.org/10.1002/jlcr.4010

Zobrazit plný text záznamu

Plný text ve formátu HTML

Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2

Autor: Odey Bsharat, Michael G. J. Doyle, Maxime Munch, Braeden A. Mair, Christopher J. C. Cooze, Volker Derdau, Armin Bauer, Duanyang Kong, Benjamin H. Rotstein, Rylan J. Lundgren

Publikováno v: Nature Chemistry. 14:1367-1374

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87cb406c34e6006ff898999e60974cbc
https://doi.org/10.1038/s41557-022-01074-0

Zobrazit plný text záznamu

Iridium‐Catalyzed CH Functionalizations with Hydrogen Isotopes

Autor: Volker Derdau

Publikováno v: Handbook of CH-Functionalization. :1-27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e42261cfd5331d28cd229d302cf17a64
https://doi.org/10.1002/9783527834242.chf0209

Zobrazit plný text záznamu

Small‐scale two‐dimensional liquid chromatography for a preparative re‐purification of a highly labile tritium‐labeled compound

Autor: Martin Sandvoss, Christian Klaus, Remo Weck, Volker Derdau, Matthias Schiell

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4b84e4c53587c80117edbf1c0b98237
https://doi.org/10.1002/jlcr.4028

Zobrazit plný text záznamu

Hydrogen Isotope Exchange by Homogeneous Iridium Catalysis in Aqueous Buffers with Deuterium or Tritium Gas

Autor: Carla Marie Stork, Remo Weck, Mégane Valero, Henrik Kramp, Stefan Güssregen, Siegfried R. Waldvogel, Anna Sib, Volker Derdau

Publikováno v: Angewandte Chemie International Edition.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f026ec87d8676cb450a0ece37da1044
https://doi.org/10.1002/anie.202301512

Zobrazit plný text záznamu

Photoredox-Catalyzed Site-Selective Generation of Carbanions from C(sp3)–H Bonds in Amines

Autor: Kathiravan Murugesan, Karsten Donabauer, Rok Narobe, Volker Derdau, Armin Bauer, Burkhard König

Publikováno v: ACS Catalysis. 12:3974-3984

The selective activation of sp3 carbon–hydrogen bonds in the presence of multiple C–H bonds is challenging and remains of supreme importance in chemical research. Late-stage modification of complex molecules via sp3 C–H activation is of high pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f992d7bf3e8ff08cc48882c9fdd2b09
https://doi.org/10.1021/acscatal.2c00662

Zobrazit plný text záznamu

Deuterated drugs and biomarkers in the COVID-19 pandemic

Autor: Ross D. Jansen-van Vuuren, Luka Jedlovčnik, Janez Košmrlj, Thomas E. Massey, Volker Derdau

Publikováno v: ACS omega, vol. 7, no. 46, pp. 41840-41858, 2022.

Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially identified in Wuhan (China) in December 2019, COVID-19 rapidly spread globally, resulting in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac91b7353ca799186809d23788c7730
https://repozitorij.uni-lj.si/Dokument.php?id=166560&dn=

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání