Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Volkan Yazar"'
Autor:
Volkan Yazar, Julia K. Kühlwein, Antje Knehr, Veselin Grozdanov, Arif B. Ekici, Albert C. Ludolph, Karin M. Danzer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Epigenetic remodeling is emerging as a critical process for several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Genetics alone fails to explain the etiology of ALS, the investigation of the epigenome might ther
Externí odkaz:
https://doaj.org/article/fb52f08c0f9a400bb1d1d7e0a7c1a080
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 553-565 (2023)
Homeostatic restoration of an inflammatory response requires quenching of the immune system after pathogen threats vanish. A continued assault orchestrated by host defense results in tissue destruction or autoimmunity. A151 is the epitome of syntheti
Externí odkaz:
https://doaj.org/article/b69edf08eb7d40f583c41e62c6e26e45
Autor:
Sérgio P. Camões, Ozlem Bulut, Volkan Yazar, Maria M. Gaspar, Sandra Simões, Rita Ferreira, Rui Vitorino, Jorge M. Santos, Ihsan Gursel, Joana P. Miranda
Publikováno v:
Journal of Advanced Research, Vol 41, Iss , Pp 113-128 (2022)
Introduction: Non-healing wounds remain a major burden due to the lack of effective treatments. Mesenchymal stem cell-derived exosomes (MSC-Exo) have emerged as therapeutic options given their pro-regenerative and immunomodulatory features. Still, li
Externí odkaz:
https://doaj.org/article/dc6d07a5a377457f891f656708724ed4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The transcriptional repressor called parkin interacting substrate (PARIS; ZNF746) was initially identified as a novel co-substrate of parkin and PINK1 that leads to Parkinson’s disease (PD) by disrupting mitochondrial biogenesis through pe
Externí odkaz:
https://doaj.org/article/b3049af49e7a40df8697aa04359b1412
Autor:
Ana S. Serras, Sérgio P. Camões, Bernardo Antunes, Vera M. Costa, Flávio Dionísio, Volkan Yazar, Rui Vitorino, Fernando Remião, Matilde Castro, Nuno G. Oliveira, Joana P. Miranda
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13072 (2021)
Doxorubicin (Dox) is one of the most widely used treatments for breast cancer, although limited by the well-documented cardiotoxicity and other off-target effects. Mesenchymal stem cell (MSC) secretome has shown immunomodulatory and regenerative prop
Externí odkaz:
https://doaj.org/article/456da593d57343cc88b589ce85e0851e
Publikováno v:
Journal of Parkinson's Disease. 13:145-164
Regulation of gene expression by epigenetic modifications means lasting and heritable changes in the function of genes without alterations in the DNA sequence. Of all epigenetic mechanisms identified thus far, DNA methylation has been of particular i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a790b1669c796f7145af38521f8b4d09
https://doi.org/10.3233/jpd-223517
https://doi.org/10.3233/jpd-223517
Autor:
Volkan Yazar, Wolfgang P Ruf, Antje Knehr, Kornelia Günther, Ole Ammerpohl, Karin M Danzer, Albert C Ludolph
Publikováno v:
Epigenetics Insights 16, 251686572311721 (2023). doi:10.1177/25168657231172159
ALS is a fatal motor neuron disease that displays a broad variety of phenotypes ranging from early fatal courses to slowly progressing and rather benign courses. Such divergence can also be seen in genetic ALS cases with varying phenotypes bearing sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10d28baf65e6f70afa59fe39534a61c
https://pub.dzne.de/record/257896
https://pub.dzne.de/record/257896
Autor:
Ulku Guler, Muzaffer Yildirim, Volkan Yazar, Deniz Karakaya, Tugce Yildirim, Eda Çiftci Dede, Fehime Kara Eroglu, Ihsan Gursel, Tülin Güngör, Evra Çelikkaya, Nilsu Turay, Mehmet Bülbül, Petek Korkusuz, Bekir Salih
Publikováno v:
American Journal of Physiology: Renal Physiology
Since previous research suggests a role of a circulating factor in the pathogenesis of steroid-sensitive nephrotic syndrome (NS), we speculated that circulating plasma extracellular vesicles (EVs) are a candidate source of such a soluble mediator. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2c6a0ff9925c73a31e95c1999caf9d
https://doi.org/10.1152/ajprenal.00097.2021
https://doi.org/10.1152/ajprenal.00097.2021
Autor:
Vera Marisa Costa, Nuno G. Oliveira, Matilde Castro, Bernardo Antunes, Volkan Yazar, Ana S. Serras, Joana P. Miranda, Fernando Remião, S.P. Camões, Flávio Dionísio, Rui Vitorino
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13072
International Journal of Molecular Sciences, Vol 22, Iss 13072, p 13072 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13072
International Journal of Molecular Sciences, Vol 22, Iss 13072, p 13072 (2021)
Doxorubicin (Dox) is one of the most widely used treatments for breast cancer, although limited by the well-documented cardiotoxicity and other off-target effects. Mesenchymal stem cell (MSC) secretome has shown immunomodulatory and regenerative prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16212c1eb8e1caae39e9bbfa97f5f011
http://europepmc.org/articles/PMC8657836
http://europepmc.org/articles/PMC8657836
Autor:
Gamze Aykut, Mayda Gursel, Fuat Cem Yagci, Volkan Yazar, Ozlem Bulut, Ihsan Gursel, Dennis M. Klinman, Tugce Yildirim, Gizem Kilic
Publikováno v:
Int Immunol
International Immunology
International Immunology
Immune-mediated inflammation must be down-regulated to facilitate tissue remodeling during homeostatic restoration of an inflammatory response. Uncontrolled or over-exuberant immune activation can cause autoimmune diseases, as well as tissue destruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f3ef19d257a229f6dde526b5e0182d
https://doi.org/10.1093/intimm/dxz059
https://doi.org/10.1093/intimm/dxz059