Accelerated long-term forgetting in healthy older adults predicts cognitive decline over 1 year

Autor: Alfie R. Wearn, Esther Saunders-Jennings, Volkan Nurdal, Emma Hadley, Michael J. Knight, Margaret Newson, Risto A. Kauppinen, Elizabeth J. Coulthard

Publikováno v: Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-9 (2020)

Abstract Background Here, we address a pivotal factor in Alzheimer’s prevention—identifying those at risk early, when dementia can still be avoided. Recent research highlights an accelerated forgetting phenotype as a risk factor for Alzheimer’s

Externí odkaz: https://doaj.org/article/c0629d0866cd4c52b30c8136d4922930

T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment

Autor: Alfie R. Wearn, Volkan Nurdal, Esther Saunders-Jennings, Michael J. Knight, Christopher R. Madan, Sean-James Fallon, Hanna K. Isotalus, Risto A. Kauppinen, Elizabeth J. Coulthard

Publikováno v: NeuroImage, Vol 238, Iss , Pp 118214- (2021)

A better understanding of early brain changes that precede loss of independence in diseases like Alzheimer's disease (AD) is critical for development of disease-modifying therapies. Quantitative MRI, such as T2 relaxometry, can identify microstructur

Externí odkaz: https://doaj.org/article/a5bdcccec8ff4f3e826402421b5b6e00

Accelerated long-term forgetting in healthy older adults predicts cognitive decline over 1 year

Autor: Margaret Newson, Alfie Wearn, Michael J. Knight, Esther Saunders-Jennings, Emma Hadley, Elizabeth Coulthard, Volkan Nurdal, Risto A. Kauppinen

Publikováno v: Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-9 (2020)
Alzheimer's Research & Therapy

Background Here, we address a pivotal factor in Alzheimer’s prevention—identifying those at risk early, when dementia can still be avoided. Recent research highlights an accelerated forgetting phenotype as a risk factor for Alzheimer’s disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d0577ae50c92b7cd652c96c16c259f
http://link.springer.com/article/10.1186/s13195-020-00693-4

The effect of repetition priming on implicit recognition memory as measured by Fast Periodic Visual Stimulation and EEG

Autor: Graeme Fairchild, George Stothart, Volkan Nurdal

Publikováno v: Nurdal, V, Fairchild, G & Stothart, G 2021, ' The effect of repetition priming on implicit recognition memory as measured by Fast Periodic Visual Stimulation and EEG ', International Journal of Psychophysiology, vol. 161, pp. 44-52 . https://doi.org/10.1016/j.ijpsycho.2021.01.009

Introduction: The development of rapid and reliable neural measures of memory is an important goal of cognitive neuroscience research and clinical practice. Fast Periodic Visual Stimulation (FPVS) is a recently developed electroencephalography (EEG)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138414cc6cff73a0987897e1a3acbda7
https://purehost.bath.ac.uk/ws/files/218095564/The_effect_of_repetition_priming_on_implicit_recognition_memory_as_measured_by_FPVS_and_EEG.pdf

T2 heterogeneity: a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment

Autor: Risto A. Kauppinen, Michael J. Knight, Alfie Wearn, Esther Saunders-Jennings, Demitra Tsivos, Volkan Nurdal, Elizabeth Coulthard, Hanna K. Isotalus, Serena Dillon

Publikováno v: Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Wearn, A R, Nurdal, V, Saunders-Jennings, E, Knight, M J, Isotalus, H K, Dillon, S, Tsivos, D, Kauppinen, R A & Coulthard, E J 2020, ' T2 heterogeneity : a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment ', Alzheimer's Research and Therapy, vol. 12, 105 (2020) . https://doi.org/10.1186/s13195-020-00672-9

Background Early Alzheimer’s disease (AD) diagnosis is vital for development of disease-modifying therapies. Prior to significant brain tissue atrophy, several microstructural changes take place as a result of Alzheimer’s pathology. These include

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08964a5b938171e8177775f66937611
https://pubmed.ncbi.nlm.nih.gov/32912337