Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Volkan, I."'
Autor:
Ella A. Eklund, Ali Mourad, Clotilde Wiel, Sama I. Sayin, Henrik Fagman, Andreas Hallqvist, Volkan I. Sayin
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundKRAS mutation status is a well-established independent prognostic factor in advanced non-small cell lung cancer (NSCLC), yet its role in early-stage disease is unclear. Here, we investigate the prognostic value of combining survival data on
Externí odkaz:
https://doaj.org/article/7f620151d599452782b18578119a2487
Autor:
Maria Schwarz, Caroline E. Meyer, Alina Löser, Kristina Lossow, Julian Hackler, Christiane Ott, Susanne Jäger, Isabelle Mohr, Ella A. Eklund, Angana A. H. Patel, Nadia Gul, Samantha Alvarez, Ilayda Altinonder, Clotilde Wiel, Maria Maares, Hajo Haase, Anetta Härtlova, Tilman Grune, Matthias B. Schulze, Tanja Schwerdtle, Uta Merle, Hans Zischka, Volkan I. Sayin, Lutz Schomburg, Anna P. Kipp
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Selenium homeostasis depends on hepatic biosynthesis of selenoprotein P (SELENOP) and SELENOP-mediated transport from the liver to e.g. the brain. In addition, the liver maintains copper homeostasis. Selenium and copper metabolism are invers
Externí odkaz:
https://doaj.org/article/30d9f9cc9e844e7286b4772f5fc6f92f
Autor:
Haidong Yao, Xue Chen, Ting Wang, Muhammad Kashif, Xi Qiao, Elin Tüksammel, Lars-Gunnar Larsson, Sam Okret, Volkan I. Sayin, Hong Qian, Martin O. Bergo
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112961- (2023)
Summary: Refractory and relapsed B cell lymphomas are often driven by the difficult-to-target oncogene MYC. Here, we report that high MYC expression stimulates proliferation and protects B lymphoma cells from apoptosis under normal oxidative stress l
Externí odkaz:
https://doaj.org/article/d1fd8139a331432ca6eb3f0f006f4426
Autor:
Moreno, Rita, Casares, Laura, Higgins, Maureen, Ali, Kevin X., Honda, Tadashi, Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., de la Vega, Laureano
Publikováno v:
In Free Radical Biology and Medicine October 2022 191:203-211
Autor:
Malmhäll-Bah, Eric, Andersson, Karin M.E., Erlandsson, Malin C., Akula, Murali K., Brisslert, Mikael, Wiel, Clotilde, El Zowalaty, Ahmed E., Sayin, Volkan I., Bergö, Martin O., Bokarewa, Maria I.
Publikováno v:
In Journal of Autoimmunity June 2022 130
Autor:
Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano
Publikováno v:
In Redox Biology May 2022 51
Autor:
Nikita Dutta, Anna Rohlin, Ella A. Eklund, Maria K. Magnusson, Frida Nilsson, Levent M. Akyürek, Per Torstensson, Volkan I. Sayin, Anna Lundgren, Andreas Hallqvist, Sukanya Raghavan
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
ObjectivesImmunotherapy by blocking programmed death protein-1 (PD-1) or programmed death protein-ligand1 (PD-L1) with antibodies (PD-1 blockade) has revolutionized treatment options for patients with non-small cell lung cancer (NSCLC). However, the
Externí odkaz:
https://doaj.org/article/ad6b94c7e52544b99cb293b558c87c00
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Laura Casares, Rita Moreno, Kevin X. Ali, Maureen Higgins, Sharadha Dayalan Naidu, Graham Neill, Lena Cassin, Anders E. Kiib, Esben B. Svenningsen, Alberto Minassi, Tadashi Honda, Thomas B. Poulsen, Clotilde Wiel, Volkan I. Sayin, Albena T. Dinkova-Kostova, David Olagnier, Laureano de la Vega
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102291- (2022)
The transcription factor BACH1 is a potential therapeutic target for a variety of chronic conditions linked to oxidative stress and inflammation, as well as cancer metastasis. However, only a few BACH1 degraders/inhibitors have been described. BACH1
Externí odkaz:
https://doaj.org/article/1416ed819aa4406aaf232a9276b3919d
Autor:
LeBoeuf, Sarah E., Wu, Warren L., Karakousi, Triantafyllia R., Karadal, Burcu, Jackson, S. RaElle, Davidson, Shawn M., Wong, Kwok-Kin, Koralov, Sergei B., Sayin, Volkan I., Papagiannakopoulos, Thales
Publikováno v:
In Cell Metabolism 4 February 2020 31(2):339-350