Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Volha I Summerhill"'
Autor:
Alexander V. Blagov, Volha I. Summerhill, Vasily N. Sukhorukov, Elena B. Zhigmitova, Anton Y. Postnov, Alexander N. Orekhov
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The excessive production of various reactive oxidant species over endogenous antioxidant defense mechanisms leads to the development of a state of oxidative stress, with serious biological consequences. The consequences of oxidative stress depend on
Externí odkaz:
https://doaj.org/article/57ee846be624474aa820b9c144dc575a
Publikováno v:
Current pharmaceutical design. 28(22)
Abstract: Polysaccharides (PSs) of plant origin have a variety of biological activities, including antiatherosclerotic, but their use in atherosclerosis therapy is hindered by insufficient knowledge based on the cellular and molecular mechanisms of a
Autor:
Vasily N. Sukhorukov, Ali H. Eid, Igor A. Sobenin, Ludmila V. Nedosugova, Alexander N. Orekhov, Volha I Summerhill
Publikováno v:
Biomolecular Concepts, Vol 12, Iss 1, Pp 55-67 (2021)
Abdominal aortic aneurysm (AAA) is a complex degenerative vascular disease, with considerable morbidity and mortality rates among the elderly population. The mortality of AAA is related to aneurysm expansion (the enlargement of the aortic diameter up
Autor:
Volha I Summerhill, Andrey V. Grechko, Alexander N. Orekhov, Elena B. Romanenko, Nataliya V. Mushenkova, Dongwei Zhang
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 2992, p 2992 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 2992, p 2992 (2020)
Atherosclerosis is a lipoprotein-driven inflammatory disorder leading to a plaque formation at specific sites of the arterial tree. After decades of slow progression, atherosclerotic plaque rupture and formation of thrombi are the major factors respo
Autor:
Alexei Gratchev, Nikita G. Nikiforov, S. S. Pintus, Kathy K Foxx, Alexandra A. Melnichenko, Vasily N. Sukhorukov, Volha I Summerhill, Daria Stelmashenko, Wei-Kai Wu, Philip Stegmaier, Yumiko Oishi, Alexander E. Kel, Igor A. Sobenin, Marina V. Kubekina, Alexander N. Orekhov, Ichiro Manabe, Reinhard Wetzker
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3, p 817 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3, p 817 (2020)
Excessive accumulation of lipid inclusions in the arterial wall cells (foam cell formation) caused by modified low-density lipoprotein (LDL) is the earliest and most noticeable manifestation of atherosclerosis. The mechanisms of foam cell formation a
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5547 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Atherosclerosis is a complex multifactorial disease that, despite advances in lifestyle management and drug therapy, remains to be the major cause of high morbidity and mortality rates from cardiovascular diseases (CVDs) in industrialized countries.
Autor:
Timur Fatkhudinov, Volha I Summerhill, Elena Khramtsova, Alexander N. Orekhov, G. B. Bol’shakova
Publikováno v:
Stem Cells: From Myth to Reality and Evolving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4b98d7ffd2212b994448eb223c24de
https://doi.org/10.1515/9783110642438-003
https://doi.org/10.1515/9783110642438-003
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030169077
Pericytes are pluripotent cells found in the vascular wall of both capillaries and large blood vessels. Pericytes are highly heterogeneous cells in terms of phenotype, tissue distribution, origin and functions, and they play an important role in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb2aa441a10c4a08482e45fb0eb6661
https://doi.org/10.1007/978-3-030-16908-4_13
https://doi.org/10.1007/978-3-030-16908-4_13
Autor:
Veronika A. Myasoedova, Alexander N. Orekhov, Paolo Poggio, Volha I Summerhill, Donato Moschetta
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5620, p 5620 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in developed countries predominantly affecting the elderly population therefore posing a large economic burden. It is a gradually progressive condition ranging from mild v
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3561 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Lipid accumulation in the arterial wall is a crucial event in the development of atherosclerotic lesions. Circulating low-density lipoprotein (LDL) is the major source of lipids that accumulate in the atherosclerotic plaques. It was discovered that n