Multi-Omic Analysis of Esophageal Adenocarcinoma Uncovers Candidate Therapeutic Targets and Cancer-Selective Posttranscriptional Regulation

Autor: Fitzgerald, Rebecca C., Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Loreno, Christine, Redmond, Aisling M., Abbas, Sujath, Freeman, Adam, Smyth, Elizabeth C., O'Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Cheah, Calvin, Coles, Hannah, Millington, Curtis, Devonshire, Ginny, Eldridge, Matthew, Secrier, Maria, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Hardwick, Richard H., Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Sharrocks, Andrew, Preston, Shaun R., Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O'Neill, J Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Contino, Gianmarco, Underwood, Timothy J., Walker, Robert C., Grace, Ben L., Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Chan, David, Cheong, Ed, Kumar, Bhaskar, Sreedharan, L., Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Scott, Michael, Sothi, Sharmila, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Moorthy, Krishna, Grabowska, Anna, Turkington, Richard, McManus, Damian, Coleman, Helen, Petty, Russell D., Bartlet, Freddie, O'Neill, J. Robert, Yébenes Mayordomo, Marcos, Mitulović, Goran, Al Shboul, Sofian, Bedran, Georges, Faktor, Jakub, Hernychova, Lenka, Uhrik, Lukas, Gómez-Herranz, Maria, Kocikowski, Mikołaj, Vojtěšek, Bořivoj, Arends, Mark J., Hupp, Ted, Alfaro, Javier Antonio

Publikováno v: In Molecular & Cellular Proteomics June 2024 23(6)

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ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation

Autor: Smith Graeme, DiRenzo James, Gueven Nuri, Hrstka Roman, Nekulova Marta, Finlan Lee E, Holcakova Jitka, Craig Ashley L, Hupp Ted R, Vojtesek Borivoj

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 195 (2010)

Abstract Background ΔNp63α is an epithelial progenitor cell marker that maintains epidermal stem cell self-renewal capacity. Previous studies revealed that UV-damage induced p53 phosphorylation is confined to ΔNp63α-positive cells in the basal la

Externí odkaz: https://doaj.org/article/f36bedf709db4e8b81ccf5eef7457eca

In Vitro Cross-Linking MS Reveals SMG1–UPF2–SMG7 Assembly as Molecular Partners within the NMD Surveillance.

Autor: Padariya, Monikaben¹ (AUTHOR) monikaben.padariya@ug.edu.pl, Vojtesek, Borivoj² (AUTHOR) vojtesek@mou.cz, Hupp, Ted^1,3 (AUTHOR), Kalathiya, Umesh¹ (AUTHOR) monikaben.padariya@ug.edu.pl

Publikováno v: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 6, p3182. 16p.

A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder

Autor: Kaldmäe, Margit, Vosselman, Thibault, Zhong, Xueying, Lama, Dilraj, Chen, Gefei, Saluri, Mihkel, Kronqvist, Nina, Siau, Jia Wei, Ng, Aik Seng, Ghadessy, Farid J., Sabatier, Pierre, Vojtesek, Borivoj, Sarr, Médoune, Sahin, Cagla, Österlund, Nicklas, Ilag, Leopold L., Väänänen, Venla A., Sedimbi, Saikiran, Arsenian-Henriksson, Marie, Zubarev, Roman A., Nilsson, Lennart, Koeck, Philip J.B., Rising, Anna, Abelein, Axel, Fritz, Nicolas, Johansson, Jan, Lane, David P., Landreh, Michael

Publikováno v: In Structure 5 May 2022 30(5):733-742