Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vojtěch Vyklický"'
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 8, Iss 6, Pp 1550037-1-1550037-14 (2015)
The time- and spectral-resolved set-up for measurements of weak infrared luminescence of photosensitizers (PSs) and singlet oxygen using optical lightguides was used on skin of laboratory animals in vivo. Wistar rats with abdominal incisions treated
Externí odkaz:
https://doaj.org/article/8751cf91e3564d198fbf0711f3f3ed35
Autor:
Julia Bleier, Philipe Ribeiro Furtado de Mendonca, Chris H. Habrian, Cherise Stanley, Vojtech Vyklicky, Ehud Y. Isacoff
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114634- (2024)
Summary: N-methyl-D-aspartate receptors are ionotropic glutamate receptors that mediate synaptic transmission and plasticity. Variable GluN2 subunits in diheterotetrameric receptors with identical GluN1 subunits set very different functional properti
Externí odkaz:
https://doaj.org/article/35058ea258dd4a0490d338577b6e17af
Publikováno v:
Journal of Luminescence. 143:729-733
Spectral- and time-resolved infrared phosphorescence set-up was adapted for detection from surfaces of solid samples by utilizing fiber optics. Its abilities are demonstrated on the detection of singlet oxygen photosensitization by intrinsic (protopo
Publikováno v:
Journal of Molecular Structure. :153-156
Comparison of photosensitization of singlet oxygen by anionic (TPPS 4 ) and cationic (TMPyP) water-soluble photosensitizers based on direct time- and spectral-resolved luminescence of both the photosensitizer and singlet oxygen is presented. Concentr
Publikováno v:
Journal of Luminescence. 131:442-444
It was shown that lipids substantially influence singlet oxygen lifetime. Question arises whether photosensitizers triplet states and excitation energy transfer to oxygen are also affected by lipids. In this contribution, the influence of lipids on e
Autor:
Barbora Krausova, Miloš Buděšínský, Ladislav Vyklický, Vojtěch Vyklický, Vladimír Pouzar, Ivan Černý
Publikováno v:
Steroids. 77(12)
During an initial study in searching for the alternative derivatives suitable for photolabeling of neuroactive steroids, perfluorobenzoates and perfluorobenzamides in position 17 of 5β-androstan-3α-ol were synthesized from the corresponding 17-hydr
Autor:
Vladimír Pouzar, Hana Chodounska, Ladislav Vyklický, Ivan Černý, Jiřina Borovská, Vojtěch Vyklický, Lukáš Vidrna
Publikováno v:
Steroids. 76(10-11)
Analogs of pregnanolone (3α-hydroxy-5β-pregnan-20-one), modified in position 17 were prepared. Compounds with 20-keto pregnane side chain replaced completely by azide (17α- and 17β-azido-5β-androstan-3α-ol), compounds with its part replaced (20
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
N-Methyl-D-aspartate receptors (NMDARs) activation involves closure of the GluN1 and GluN2 subunit ligand binding domains, which is regulated allosterically by the amino-terminal domain (ATD). Here, smFRET, used to monitor conformational rearrangemen
Externí odkaz:
https://doaj.org/article/8e4c29ebad794dcf8259b791a65adee9
Autor:
Chris H. Habrian, Joshua Levitz, Vojtech Vyklicky, Zhu Fu, Adam Hoagland, Isabelle McCort-Tranchepain, Francine Acher, Ehud Y. Isacoff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Metabotropic glutamate receptors (mGluRs) are dimeric G-protein–coupled receptors that operate at neural synapses. Here authors use FRET assays in live cells to monitor mGluR2/7’s activation and reveal how heterodimerization can alter the glutama
Externí odkaz:
https://doaj.org/article/118cbbd567084baca674e6ab3894b693
Autor:
Kristina Holubova, Marketa Chvojkova, Barbora Hrcka Krausova, Vojtech Vyklicky, Eva Kudova, Hana Chodounska, Ladislav Vyklicky, Karel Vales
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 1026 (2021)
Evidence from clinical and preclinical studies implicates dysfunction of N-methyl-D-aspartate receptors (NMDARs) in schizophrenia progression and symptoms. We investigated the antipsychotic effect of two neuroactive steroids in an animal model of sch
Externí odkaz:
https://doaj.org/article/d697bc39daff4bd4944bbb038ff09afb