Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome

Autor: Hoeks, Marlijn, Bagguley, Tim, van Marrewijk, Corine, Smith, Alex, Bowen, David, Culligan, Dominic, Kolade, Seye, Symeonidis, Argiris, Garelius, Hege, Spanoudakis, Michail, Langemeijer, Saskia, Roelofs, Rian, Wiegerinck, Erwin, Tatic, Aurelia, Killick, Sally, Panagiotidis, Panagiotis, Stanca, Oana, Hellström-Lindberg, Eva, Cermak, Jaroslav, van der Klauw, Melanie, Wouters, Hanneke, van Kraaij, Marian, Blijlevens, Nicole, Swinkels, Dorine W., de Witte, Theo, Stauder, R., Walder, A., Pfeilstöcker, M., Schoenmetzler-Makrai, A., Burgstaller, S., Thaler, J., Mandac Rogulj, I., Krejci, M., Voglova, J., Rohon, P., Jonasova, A., Cermak, J., Mikulenkova, D., Hochova, I., Jensen, P. D., Holm, M. S., Kjeldsen, L., Dufva, I. H., Vestergaard, H., Re, D., Slama, B., Fenaux, P., Choufi, B., Cheze, S., Klepping, D., Salles, B., de Renzis, B., Willems, L., De Prost, D., Gutnecht, J., Courby, S., Siguret, V., Tertian, G., Pascal, L., Chaury, M., Wattel, E., Guerci, A., Legros, L., Itzykson, R., Ades, L., Isnard, F., Sanhes, L., Benramdane, R., Stamatoullas, A., Amé, S., Beyne-Rauzy, O., Gyan, E., Platzbecker, U., Badrakan, C., Germing, U., Lübbert, M., Schlenk, R., Kotsianidis, I., Tsatalas, C., Pappa, V., Galanopoulos, A., Michali, E., Panagiotidis, P., Viniou, N., Katsigiannis, A., Roussou, P., Terpos, E., Kostourou, A., Kartasis, Z., Pouli, A., Palla, K., Briasoulis, V., Hatzimichael, E., Vassilopoulos, G., Symeonidis, A., Kourakli, A., Zikos, P., Anagnostopoulos, A., Kotsopoulou, M., Megalakaki, K., Protopapa, M., Vlachaki, E., Konstantinidou, P., Stemer, G., Nemetz, A., Gotwin, U., Cohen, O., Koren, M., Levy, E., Greenbaum, U., Gino-Moor, S., Price, M., Ofran, Y., Winder, A., Goldshmidt, N., Elias, S., Sabag, R., Hellman, I., Ellis, M., Braester, A., Rosenbaum, H., Berdichevsky, S., Itzhaki, G., Wolaj, O., Yeganeh, S., Katz, O., Filanovsky, K., Dali, N., Mittelman, M., Malcovati, L., Fianchi, L., vd Loosdrecht, A., Matthijssen, V., Herbers, A., Pruijt, H., Aboosy, N., de Vries, F., Velders, G., Jacobs, E., Langemeijer, S., MacKenzie, M., Lensen, C., Kuijper, P., Madry, K., Camara, M., Almeida, A., Vulkan, G., Stanca Ciocan, O., Tatic, A., Savic, A., Pedro, C., Xicoy, B., Leiva, P., Munoz, J., Betes, V., Benavente, C., Lozano, M., Martinez, M., Iniesta, P., Bernal, T., Diez Campelo, M., Tormo, D., Andreu Lapiedra, R., Sanz, G., Hesse Sundin, E., Garelius, H., Karlsson, C., Antunovic, P., Jönsson, A., Brandefors, L., Nilsson, L., Kozlowski, P., Hellstrom-Lindberg, E., Grövdal, M., Larsson, K., Wallvik, J., Lorenz, F., Ejerblad, E., Culligan, D., Craddock, C., Kolade, S., Cahalin, P., Killick, S., Ackroyd, S., Wong, C., Warren, A., Drummond, M., Hall, C., Rothwell, K., Green, S., Ali, S., Bowen, D., Karakantza, M., Dennis, M., Jones, G., Parker, J., Bowen, A., Radia, R., Das-Gupta, E., Vyas, P., Nga, E., Creagh, D., Ashcroft, J., Mills, J., Bond, L.

Publikováno v: Hoeks, M, Bagguley, T, van Marrewijk, C, Smith, A, Bowen, D, Culligan, D, Kolade, S, Symeonidis, A, Garelius, H, Spanoudakis, M, Langemeijer, S, Roelofs, R, Wiegerinck, E, Tatic, A, Killick, S, Panagiotidis, P, Stanca, O, Hellström-Lindberg, E, Cermak, J, van der Klauw, M, Wouters, H, van Kraaij, M, Blijlevens, N, Swinkels, D W, de Witte, T, Stauder, R, Walder, A, Pfeilstöcker, M, Schoenmetzler-Makrai, A, Burgstaller, S, Thaler, J, Mandac Rogulj, I, Krejci, M, Voglova, J, Rohon, P, Jonasova, A, Cermak, J, Mikulenkova, D, Hochova, I, Jensen, P D, Holm, M S, Kjeldsen, L, Dufva, I H, Vestergaard, H, Re, D, Slama, B, Fenaux, P, Choufi, B, Cheze, S, Klepping, D, Salles, B, de Renzis, B, Willems, L, De Prost, D, Gutnecht, J, Courby, S, Siguret, V, Tertian, G, Pascal, L, Chaury, M, Wattel, E, Guerci, A, Legros, L, Itzykson, R, Ades, L, Isnard, F, Sanhes, L, Benramdane, R, Stamatoullas, A, Amé, S, Beyne-Rauzy, O, Gyan, E, Platzbecker, U, Badrakan, C, Germing, U, Lübbert, M, Schlenk, R, Kotsianidis, I, Tsatalas, C, Pappa, V, Galanopoulos, A, Michali, E, Panagiotidis, P, Viniou, N, Katsigiannis, A, Roussou, P, Terpos, E, Kostourou, A, Kartasis, Z, Pouli, A, Palla, K, Briasoulis, V, Hatzimichael, E, Vassilopoulos, G, Symeonidis, A, Kourakli, A, Zikos, P, Anagnostopoulos, A, Kotsopoulou, M, Megalakaki, K, Protopapa, M, Vlachaki, E, Konstantinidou, P, Stemer, G, Nemetz, A, Gotwin, U, Cohen, O, Koren, M, Levy, E, Greenbaum, U, Gino-Moor, S, Price, M, Ofran, Y, Winder, A, Goldshmidt, N, Elias, S, Sabag, R, Hellman, I, Ellis, M, Braester, A, Rosenbaum, H, Berdichevsky, S, Itzhaki, G, Wolaj, O, Yeganeh, S, Katz, O, Filanovsky, K, Dali, N, Mittelman, M, Malcovati, L, Fianchi, L, vd Loosdrecht, A, Matthijssen, V, Herbers, A, Pruijt, H, Aboosy, N, de Vries, F, Velders, G, Jacobs, E, Langemeijer, S, MacKenzie, M, Lensen, C, Kuijper, P, Madry, K, Camara, M, Almeida, A, Vulkan, G, Stanca Ciocan, O, Tatic, A, Savic, A, Pedro, C, Xicoy, B, Leiva, P, Munoz, J, Betes, V, Benavente, C, Lozano, M, Martinez, M, Iniesta, P, Bernal, T, Diez Campelo, M, Tormo, D, Andreu Lapiedra, R, Sanz, G, Hesse Sundin, E, Garelius, H, Karlsson, C, Antunovic, P, Jönsson, A, Brandefors, L, Nilsson, L, Kozlowski, P, Hellstrom-Lindberg, E, Grövdal, M, Larsson, K, Wallvik, J, Lorenz, F, Ejerblad, E, Culligan, D, Craddock, C, Kolade, S, Cahalin, P, Killick, S, Ackroyd, S, Wong, C, Warren, A, Drummond, M, Hall, C, Rothwell, K, Green, S, Ali, S, Karakantza, M, Dennis, M, Jones, G, Parker, J, Bowen, A, Radia, R, Das-Gupta, E, Vyas, P, Nga, E, Creagh, D, Ashcroft, J, Mills, J, Bond, L & the EUMDS Registry Participants 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
on behalf of the EUMDS Registry Participants 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
Hoeks, M, Bagguley, T, van Marrewijk, C, Smith, A, Bowen, D, Culligan, D, Kolade, S, Symeonidis, A, Garelius, H, Spanoudakis, M, Langemeijer, S, Roelofs, R, Wiegerinck, E, Tatic, A, Killick, S, Panagiotidis, P, Stanca, O, Hellström-Lindberg, E, Cermak, J, van der Klauw, M, Wouters, H, van Kraaij, M, Blijlevens, N, Swinkels, D W, de Witte, T, on behalf of the EUMDS Registry Participants & Vestergaard, H 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
Leukemia, 35, 1745-1750
Leukemia, 35, 1745-1750. Nature Publishing Group
Leukemia, 35(6), 1745-1750. Nature Publishing Group
Leukemia, 35, 6, pp. 1745-1750
Leukemia

Red blood cell transfusions (RBCT) remain the cornerstone of supportive care in lower-risk myelodysplastic syndrome (LRMDS) [1]. Transfusion dependency in LRMDS patients is associated with inferior outcomes, mainly attributed to severe bone marrow fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23cc5efb8d641ceed6da88864dd77a4
https://eprints.whiterose.ac.uk/165856/1/s41375_020_01022_2.pdf

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome

Autor: Hoeks, M. Bagguley, T. van Marrewijk, C. Smith, A. Bowen, D. Culligan, D. Kolade, S. Symeonidis, A. Garelius, H. Spanoudakis, M. Langemeijer, S. Roelofs, R. Wiegerinck, E. Tatic, A. Killick, S. Panagiotidis, P. Stanca, O. Hellström-Lindberg, E. Cermak, J. van der Klauw, M. Wouters, H. van Kraaij, M. Blijlevens, N. Swinkels, D.W. de Witte, T. Stauder, R. Walder, A. Pfeilstöcker, M. Schoenmetzler-Makrai, A. Burgstaller, S. Thaler, J. Mandac Rogulj, I. Krejci, M. Voglova, J. Rohon, P. Jonasova, A. Cermak, J. Mikulenkova, D. Hochova, I. Jensen, P.D. Holm, M.S. Kjeldsen, L. Dufva, I.H. Vestergaard, H. Re, D. Slama, B. Fenaux, P. Choufi, B. Cheze, S. Klepping, D. Salles, B. de Renzis, B. Willems, L. De Prost, D. Gutnecht, J. Courby, S. Siguret, V. Tertian, G. Pascal, L. Chaury, M. Wattel, E. Guerci, A. Legros, L. Itzykson, R. Ades, L. Isnard, F. Sanhes, L. Benramdane, R. Stamatoullas, A. Amé, S. Beyne-Rauzy, O. Gyan, E. Platzbecker, U. Badrakan, C. Germing, U. Lübbert, M. Schlenk, R. Kotsianidis, I. Tsatalas, C. Pappa, V. Galanopoulos, A. Michali, E. Panagiotidis, P. Viniou, N. Katsigiannis, A. Roussou, P. Terpos, E. Kostourou, A. Kartasis, Z. Pouli, A. Palla, K. Briasoulis, V. Hatzimichael, E. Vassilopoulos, G. Symeonidis, A. Kourakli, A. Zikos, P. Anagnostopoulos, A. Kotsopoulou, M. Megalakaki, K. Protopapa, M. Vlachaki, E. Konstantinidou, P. Stemer, G. Nemetz, A. Gotwin, U. Cohen, O. Koren, M. Levy, E. Greenbaum, U. Gino-Moor, S. Price, M. Ofran, Y. Winder, A. Goldshmidt, N. Elias, S. Sabag, R. Hellman, I. Ellis, M. Braester, A. Rosenbaum, H. Berdichevsky, S. Itzhaki, G. Wolaj, O. Yeganeh, S. Katz, O. Filanovsky, K. Dali, N. Mittelman, M. Malcovati, L. Fianchi, L. vd Loosdrecht, A. Matthijssen, V. Herbers, A. Pruijt, H. Aboosy, N. de Vries, F. Velders, G. Jacobs, E. Langemeijer, S. MacKenzie, M. Lensen, C. Kuijper, P. Madry, K. Camara, M. Almeida, A. Vulkan, G. Stanca Ciocan, O. Tatic, A. Savic, A. Pedro, C. Xicoy, B. Leiva, P. Munoz, J. Betes, V. Benavente, C. Lozano, M. Martinez, M. Iniesta, P. Bernal, T. Diez Campelo, M. Tormo, D. Andreu Lapiedra, R. Sanz, G. Hesse Sundin, E. Garelius, H. Karlsson, C. Antunovic, P. Jönsson, A. Brandefors, L. Nilsson, L. Kozlowski, P. Hellstrom-Lindberg, E. Grövdal, M. Larsson, K. Wallvik, J. Lorenz, F. Ejerblad, E. Culligan, D. Craddock, C. Kolade, S. Cahalin, P. Killick, S. Ackroyd, S. Wong, C. Warren, A. Drummond, M. Hall, C. Rothwell, K. Green, S. Ali, S. Karakantza, M. Dennis, M. Jones, G. Parker, J. Bowen, A. Radia, R. Das-Gupta, E. Vyas, P. Nga, E. Creagh, D. Ashcroft, J. Mills, J. Bond, L. the EUMDS Registry Participants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::35fd8624b47b93135f84f48bbb02f6a9
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3076511

P075 Characteristics of patients with therapy-related myelodysplastic syndrome

Autor: Belohlavkova, P., Voglova, J., Neuwirtova, R., Krejcova, H., Cermak, J., Vondrakova, J., Vozobulova, V., Krejci, M., Muzik, J.

Publikováno v: In Leukemia Research 2009 33 Supplement 1:S102-S102

Dasatinib treatment long-term results among imatinib-resistant/intolerant patients with chronic phase chronic myeloid leukemia are favorable in daily clinical practice.

Autor: Zackova D; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Klamova H; Institute of Hematology and Blood Transfusion, Praha, Czech Republic., Belohlavkova P; 4th Department of Internal Medicine - Hematology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Stejskal L; Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic., Necasova T; Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic., Semerad L; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Weinbergerova B; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Srbova D; Institute of Hematology and Blood Transfusion, Praha, Czech Republic., Voglova J; 4th Department of Internal Medicine - Hematology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic., Cicatkova P; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Sustkova Z; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Hornak T; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Baranova J; Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic., Prochazkova J; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic., Mayer J; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic.; Central European Institute of Technology, Brno, Czech Republic.

Publikováno v: Leukemia & lymphoma [Leuk Lymphoma] 2021 Jan; Vol. 62 (1), pp. 194-202. Date of Electronic Publication: 2020 Oct 06.

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

Autor: Fenaux, P, Mufti, Gj, Hellstrom Lindberg, E, Santini, V, Finelli, C, Giagounidis, A, Schoch, R, Gattermann, N, Sanz, G, List, A, Gore, Sd, Seymour, Jf, Bennett, Jm, Byrd, J, Backstrom, J, Zimmerman, L, Mckenzie, D, Beach, C, Silverman, Lr, Durrant, S, Enno, A, Herrmann, R, Horvath, N, Mills, A, Spencer, A, Szer, J, Gallo, J, Dunlop, L, Arthur, C, Goranov, S, Peytchev, D, Gercheva, L, Cermak, J, Voglova, J, Vey, N, Dreyfus, F, Laurent, G, Quesnel, B, Dombret, H, Stamatoullas, A, Wattel, E, Hunault Berger, M, Aul, C, Duhrsen, U, Platzbecker, U, Schmid, M, Hanel, M, Haase, D, Fiedler, W, Schmitz, N, Hofmann, W, Horst, H, Anagnostopoulos, N, Pappa, V, Papadaki, E, Zoumbos, N, Borbenyi, Z, Masszi, T, Baccarani, M, Bacigalupo, A, Corradini, P, Leone, G, Sacchi, Stefano, Bosi, A, Musto, P, Muus, P, Dmoszynska, A, Robak, T, Sulek, K, Kuliczkowski, K, Jedrzejczak, W, Zaritsky, A, Abdulkadyrov, K, Podoltseva, E, Afanasiev, B, Bargay, J, Brunet, S, Del Canizo, C, Ribera, J, Figuera Alvarez, A, Diaz Mediavilla, J, Canales, M, Ortega F, Ramos y., Nilsson, L, Olsson, A, Cavenagh, J, Parker, J, Killick, S, Kruger, A, Vyas, P, Dennis, M, Cripe, L, Dipersio, J, Emanuel, P.

Publikováno v: The Lancet. Oncology. 10(3)

Drug treatments for patients with high-risk myelodysplastic syndromes provide no survival advantage. In this trial, we aimed to assess the effect of azacitidine on overall survival compared with the three commonest conventional care regimens.In a pha

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https://pubmed.ncbi.nlm.nih.gov/19261248