Two-locus linkage analysis applied to putative quantitative trait loci for lipoprotein(a) levels

Autor: Beekman, M., Heijmans, B.T., Martin, N.G., Whitfield, J.B., Pedersen, N.L., Faire, U. de, Snieder, H., Lakenberg, N., Knijff, P. de, Frants, R.R., Ommen, G.J.B. van, Kluft, C., Vogler, G.P., Slagboom, P.E., Boomsma, D.I.

Publikováno v: Twin Research, 4, 6, 322-324

Plasma levels of lipoprotein(a) - Lp(a) - are associated with cardiovascular risk (Danesh et al., 2000) and were long believed to be influenced by the LPA locus on chromosome 6q27 only. However, a recent report of Broeckel et al. (2002) suggested the

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http://resolver.tudelft.nl/uuid:2cb52ee8-99b7-47de-9594-570027e8aae0

Evidence for a QTL at chromosome 19 determining LDL cholesterol levels in the general population

Autor: Beekman, M., Heijmans, B.T., Martin, N.G., Whitfield, J.B., Pedersen, N.L., DeFaire, U., Snieder, H., Lakenberg, N., Suchiman, H.E.D., de Knijff, P., Frants, R.R., van Ommen, G.J.B, Kluft, C., Vogler, G.P., Boomsma, D.I., Slagboom, P.E.

Publikováno v: European Journal of Human Genetics, 11(11), 845-850. Nature Publishing Group
Beekman, M, Heijmans, B T, Martin, N G, Whitfield, J B, Pedersen, N L, DeFaire, U, Snieder, H, Lakenberg, N, Suchiman, H E D, de Knijff, P, Frants, R R, van Ommen, G J B, Kluft, C, Vogler, G P, Boomsma, D I & Slagboom, P E 2003, ' Evidence for a QTL at chromosome 19 determining LDL cholesterol levels in the general population ', European Journal of Human Genetics, vol. 11, no. 11, pp. 845-850 . https://doi.org/10.1038/sj.ejhg.5201053

The genetic basis of cardiovascular disease (CVD) with its complex etiology is still largely elusive. Plasma levels of lipids and apolipoproteins are among the major quantitative risk factors for CVD and are well-established intermediate traits that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7223019398227969ad458cc80f6d5796
https://research.vu.nl/en/publications/31bca264-a2dd-43cc-b83a-4dd780ab687c

Genetics and behavioral medicine: Risk factors for cardiovascular disease

Autor: Vogler, G.P., McClearn, G.E., Snieder, H., Boomsma, D.I., Palmer, R., Knijff, P. de, Slagboom, P.E.

Publikováno v: Behavioral Medicine, 4, 22, 141-149

This is the second in a series of three articles addressing the intersection of interests in behavioral genetics and behavioral medicine. In this article, we use risk factors for cardiovascular disease as a prototypical trait for which behavioral gen

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http://resolver.tudelft.nl/uuid:d63a3d99-3c39-43d5-a856-fb39317cfa05

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