Clonal fitness inferred from time-series modelling of single-cell cancer genomes

Autor: Salehi, Sohrab, Kabeer, Farhia, Ceglia, Nicholas, Andronescu, Mirela, Williams, Marc J., Campbell, Kieran R., Masud, Tehmina, Wang, Beixi, Biele, Justina, Brimhall, Jazmine, Gee, David, Lee, Hakwoo, Ting, Jerome, Zhang, Allen W., Tran, Hoa, O’Flanagan, Ciara, Dorri, Fatemeh, Rusk, Nicole, de Algara, Teresa Ruiz, Lee, So Ra, Cheng, Brian Yu Chieh, Eirew, Peter, Kono, Takako, Pham, Jenifer, Grewal, Diljot, Lai, Daniel, Moore, Richard, Mungall, Andrew J., Marra, Marco A., Hannon, Gregory J., Battistoni, Giorgia, Bressan, Dario, Cannell, Ian Gordon, Casbolt, Hannah, Fatemi, Atefeh, Jauset, Cristina, Kovačević, Tatjana, Mulvey, Claire M., Nugent, Fiona, Ribes, Marta Paez, Pearsall, Isabella, Qosaj, Fatime, Sawicka, Kirsty, Wild, Sophia A., Williams, Elena, Laks, Emma, Li, Yangguang, O’Flanagan, Ciara H., Smith, Austin, Ruiz, Teresa, Roth, Andrew, Balasubramanian, Shankar, Lee, Maximillian, Bodenmiller, Bernd, Burger, Marcel, Kuett, Laura, Tietscher, Sandra, Windhager, Jonas, Boyden, Edward S., Alon, Shahar, Cui, Yi, Emenari, Amauche, Goodwin, Dan, Karagiannis, Emmanouil D., Sinha, Anubhav, Wassie, Asmamaw T., Caldas, Carlos, Bruna, Alejandra, Callari, Maurizio, Greenwood, Wendy, Lerda, Giulia, Eyal-Lubling, Yaniv, Rueda, Oscar M., Shea, Abigail, Harris, Owen, Becker, Robby, Grimaldi, Flaminia, Harris, Suvi, Vogl, Sara Lisa, Weselak, Joanna, Joyce, Johanna A., Watson, Spencer S., Vázquez-Garćıa, Ignacio, Tavaré, Simon, Dinh, Khanh N., Fisher, Eyal, Kunes, Russell, Walton, Nicholas A., Sa’d, Mohammad Al, Chornay, Nick, Dariush, Ali, González-Solares, Eduardo A., González-Fernández, Carlos, Yoldas, Aybüke Küpcü, Millar, Neil, Whitmarsh, Tristan, Zhuang, Xiaowei, Fan, Jean, Lee, Hsuan, Sepúlveda, Leonardo A., Xia, Chenglong, Zheng, Pu, McPherson, Andrew, Bouchard-Côté, Alexandre, Aparicio, Samuel, Shah, Sohrab P.

Publikováno v: Nature, 595 (7868)
Nature

Progress in defining genomic fitness landscapes in cancer, especially those defined by copy number alterations (CNAs), has been impeded by lack of time-series single-cell sampling of polyclonal populations and temporal statistical models1-7. Here we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7969bf64b96712c2f022b7a48930f00