Brain charts for the human lifespan

Autor: Bethlehem, RAI, Seidlitz, J, White, SR, Vogel, JW, Anderson, KM, Adamson, C, Adler, S, Alexopoulos, GS, Anagnostou, E, Areces-Gonzalez, A, Astle, DE, Auyeung, B, Ayub, M, Bae, J, Ball, G, Baron-Cohen, S, Beare, R, Bedford, SA, Benegal, V, Beyer, F, Blangero, J, Blesa Cábez, M, Boardman, JP, Borzage, M, Bosch-Bayard, JF, Bourke, N, Calhoun, VD, Chakravarty, MM, Chen, C, Chertavian, C, Chetelat, G, Chong, YS, Cole, JH, Corvin, A, Costantino, M, Courchesne, E, Crivello, F, Cropley, VL, Crosbie, J, Crossley, N, Delarue, M, Delorme, R, Desrivieres, S, Devenyi, GA, Di Biase, MA, Dolan, R, Donald, KA, Donohoe, G, Dunlop, K, Edwards, AD, Elison, JT, Ellis, CT, Elman, JA, Eyler, L, Fair, DA, Feczko, E, Fletcher, PC, Fonagy, P, Franz, CE, Galan-Garcia, L, Gholipour, A, Giedd, J, Gilmore, JH, Glahn, DC, Goodyer, IM, Grant, PE, Groenewold, NA, Gunning, FM, Gur, RE, Gur, RC, Hammill, CF, Hansson, O, Hedden, T, Heinz, A, Henson, RN, Heuer, K, Hoare, J, Holla, B, Holmes, AJ, Holt, R, Huang, H, Im, K, Ipser, J, Jack, CR, Jackowski, AP, Jia, T, Johnson, KA, Jones, PB, Jones, DT, Kahn, RS, Karlsson, H, Karlsson, L, Kawashima, R, Kelley, EA, Kern, S, Kim, KW, Kitzbichler, MG, Kremen, WS, Lalonde, F, Landeau, B

Publikováno v: Nature, vol 604, iss 7906

Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual differences in neuroimaging metrics over time, in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0dbbad4a0a8f29ce0963be7c8191588f
https://escholarship.org/uc/item/3f71f685

β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation

Autor: Mander, BA, Marks, SM, Vogel, JW, Rao, V, Lu, B, Saletin, JM, Ancoli-Israel, S, Jagust, WJ, Walker, MP

Publikováno v: Mander, BA; Marks, SM; Vogel, JW; Rao, V; Lu, B; Saletin, JM; et al.(2015). β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation. Nature Neuroscience, 18(7), 1051-1057. doi: 10.1038/nn.4035. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/6mk594jz

© 2015 Nature America, Inc. Independent evidence associates β-amyloid pathology with both non-rapid eye movement (NREM) sleep disruption and memory impairment in older adults. However, whether the influence of β-amyloid pathology on hippocampus-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::96eb7bda22749a788b1d626859c283fd
http://www.escholarship.org/uc/item/6mk594jz

Proteomic changes in Alzheimer's disease associated with progressive Aβ plaque and tau tangle pathologies.

Autor: Pichet Binette A; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden. alexa.pichet_binette@med.lu.se., Gaiteri C; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA.; Rush University Alzheimer's Disease Center, Rush University, Chicago, IL, USA., Wennström M; Cognitive Disorder Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Kumar A; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Hristovska I; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Spotorno N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Strandberg O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Mathys H; Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA.; University of Pittsburgh Brain Institute and Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Tsai LH; Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Rush University Alzheimer's Disease Center, Rush University, Chicago, IL, USA.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Vogel JW; Department of Clinical Sciences Malmö, SciLifeLab, Lund University, Lund, Sweden., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.

Publikováno v: Nature neuroscience [Nat Neurosci] 2024 Oct; Vol. 27 (10), pp. 1880-1891. Date of Electronic Publication: 2024 Aug 26.

A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.

Autor: Baumeister H; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany., Vogel JW; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden., Insel PS; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Kleineidam L; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany., Wolfsgruber S; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany., Stark M; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany., Gellersen HM; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany., Yakupov R; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany., Schmid MC; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Institute for Medical Biometry, University Hospital Bonn, 53127 Bonn, Germany., Lüsebrink F; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany., Brosseron F; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Ziegler G; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany., Freiesleben SD; German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Preis L; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Schneider LS; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Spruth EJ; German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Altenstein S; German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Lohse A; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Fliessbach K; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany., Vogt IR; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Bartels C; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075 Göttingen, Germany., Schott BH; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075 Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.; Leibniz Institute for Neurobiology, 39118 Magdeburg, Germany., Rostamzadeh A; Department of Psychiatry, Medical Faculty, University of Cologne, 50937 Cologne, Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany., Incesoy EI; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany.; Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 39120 Magdeburg, Germany., Butryn M; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany., Janowitz D; Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-Universität, 81377 Munich, Germany., Rauchmann BS; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität, 80336 Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield S10 2HQ, UK.; Department of Neuroradiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), 18147 Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, 18147 Rostock, Germany., Goerss D; German Center for Neurodegenerative Diseases (DZNE), 18147 Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, 18147 Rostock, Germany., Munk MH; German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, 72076 Tübingen, Germany., Hetzer S; Berlin Center for Advanced Neuroimaging, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., Dechent P; MR-Research in Neurosciences, Department of Cognitive Neurology, Georg-August-University Göttingen, 37075 Göttingen, Germany., Ewers M; Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-Universität, 81377 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Scheffler K; Department for Biomedical Magnetic Resonance, University of Tübingen, 72076 Tübingen, Germany., Wuestefeld A; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden., Strandberg O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden., van Westen D; Diagnostic Radiology, Institution of Clinical Sciences Lund, Lund University, 211 84 Lund, Sweden.; Image and Function, Skåne University Hospital, 211 84 Lund, Sweden., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund University, 211 84 Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, 22184 Lund, Sweden., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden., Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.; Memory Clinic, Skåne University Hospital, 205 02 Malmö, Sweden., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.; Memory Clinic, Skåne University Hospital, 205 02 Malmö, Sweden., Spottke A; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurology, University of Bonn, 53127 Bonn, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, 72076 Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research, 72076 Tübingen, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), 18147 Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, 18147 Rostock, Germany., Perneczky R; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität, 80336 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, London SW7 2AZ, UK., Buerger K; Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-Universität, 81377 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; Department of Psychiatry and Psychotherapy, Technical University of Munich, 81675 Munich, Germany.; Centre for Clinical Brain Sciences, University of Edinburgh and UK DRI, Edinburgh EH16 4SB, UK., Peters O; German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Ramirez A; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, 50931 Cologne, Germany.; Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, The University of Texas at San Antonio, San Antonio, TX 78229, USA., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075 Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.; Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal., Heneka MT; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362, Belvaux, Luxembourg., Wagner M; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany.; Center for Behavioral Brain Sciences (CBBS), Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany., Jessen F; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Psychiatry, Medical Faculty, University of Cologne, 50937 Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.; Memory Clinic, Skåne University Hospital, 205 02 Malmö, Sweden., Berron D; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.; Center for Behavioral Brain Sciences (CBBS), Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany.

Publikováno v: Brain : a journal of neurology [Brain] 2024 Jul 05; Vol. 147 (7), pp. 2400-2413.

Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.

Autor: Mastenbroek SE; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands. s.e.mastenbroek@amsterdamumc.nl.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands. s.e.mastenbroek@amsterdamumc.nl.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. s.e.mastenbroek@amsterdamumc.nl., Vogel JW; Department of Clinical Sciences Malmö, Faculty of Medicine, SciLifeLab, Lund University, Lund, Sweden., Collij LE; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Serrano GE; Banner Sun Health Research Institute, Sun City, AZ, USA., Tremblay C; Banner Sun Health Research Institute, Sun City, AZ, USA., Young AL; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Medical Image Computing, Department of Computer Science, University College London, London, UK., Arce RA; Banner Sun Health Research Institute, Sun City, AZ, USA., Shill HA; Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA., Driver-Dunckley ED; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA., Mehta SH; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA., Belden CM; Banner Sun Health Research Institute, Sun City, AZ, USA., Atri A; Banner Sun Health Research Institute, Sun City, AZ, USA.; Department of Neurology, Center for Mind/Brain Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA, USA., Choudhury P; Banner Sun Health Research Institute, Sun City, AZ, USA., Barkhof F; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands.; Institutes of Neurology & Healthcare Engineering, University College London, London, UK., Adler CH; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam University Medical Center location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Beach TG; Banner Sun Health Research Institute, Sun City, AZ, USA., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 15; Vol. 15 (1), pp. 5133. Date of Electronic Publication: 2024 Jun 15.