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Akademický článek

Isolation and Cytotoxic Activity Test of Alkaloids from Dichloromethane Fraction of Bark of Tampa Badak (Voacanga foetida (Blume) Rolfe) Against T47D Cell Line

Autor: Adriani Susanty, Nurdina Putri, Ihsan Ikhtiarudin, Novia Sinata, Dira Dira, Fatma Sri Wahyuni, Dachriyanus Dachriyanus

Publikováno v: Journal of Tropical Pharmacy and Chemistry, Vol 7, Iss 2 (2023)

Cancer is a problem in the health sector because this disease has an increasing incidence of morbidity and mortality. While the treatment still leaves some drug side effects, which cause discomfort for cancers sufferers. The arises because most cance

Externí odkaz: https://doaj.org/article/5dca3ce57d4041f29901142ce4be7be5

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Akademický článek

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Akademický článek

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Akademický článek

In Vitro and In Silico Antistaphylococcal Activity of Indole Alkaloids Isolated from Tabernaemontana cymosa Jacq (Apocynaceae)

Autor: Yina Pájaro-González, Julián Cabrera-Barraza, Geraldine Martelo-Ramírez, Andrés F. Oliveros-Díaz, Juan Urrego-Álvarez, Wiston Quiñones-Fletcher, Fredyc Díaz-Castillo

Publikováno v: Scientia Pharmaceutica, Vol 90, Iss 2, p 38 (2022)

The species of the genus Tabernaemontana have a long tradition of use in different pathologies of infectious origins; the antibacterial, antifungal, and antiviral effects related to the control of the pathologies where the species of this genus are u

Externí odkaz: https://doaj.org/article/0fa12adfac8e4a30be01379b74800129

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Efficient Access to the Iboga Skeleton: Optimized Procedure to Obtain Voacangine from Voacanga africana Root Bark

Autor: Leopoldo Suescun, Gustavo Seoane, Alejandro Peixoto de Abreu Lima, Catherine Fagundez, Bruno González, Diver Sellanes, Ignacio Carrera

Publikováno v: ACS Omega
ACS Omega, Vol 6, Iss 26, Pp 16755-16762 (2021)

Iboga alkaloids are a group of monoterpenoid indole alkaloids with promising and intriguing biological activities. Ibogaine is the representative member of the series and has become widely known as a potent atypical psychedelic with promising effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db53db316e324846699a619e35c7c7b5
http://europepmc.org/articles/PMC8264847

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Akademický článek

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A recepto-informatics study of the phytocompounds of Tabernaemontana divaricata (L.) having potential anticancer efficacy for breast cancer

Autor: Sanjana Bhagat, Dhiraj Kumar

Publikováno v: Journal of Medicinal Plants Studies. 9:14-20

Background: Breast cancer could be a serious global health concern causing the best mortality rate in females. Available synthetic medicine to treat breast cancer are marred by extreme toxicity problems and recommend some alternate route to handle th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d523251eb2c231886d07eb465c693f18
https://doi.org/10.22271/plants.2021.v9.i1a.1242

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In silico screening of anticholinesterase alkaloids for cyclooxygenase-2 (COX-2) and matrix metalloproteinase 8 (MMP-8) inhibitory potentials as multi-target inhibitors of Alzheimer’s disease

Autor: Kayode Ezekiel Adewole, Ahmed Adebayo Ishola

Publikováno v: Medicinal Chemistry Research. 28:1704-1717

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with yet no effective drug treatment; although several anticholinesterases are being used to offer relief from the symptoms of the disease. Recent studies have indicated that over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6769c878807e2ff854d4363b5b928d8f
https://doi.org/10.1007/s00044-019-02407-4

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A new cytotoxic indole alkaloid from Tabernaemontana inconspicua stapf

Autor: Emmanuel Mfotie Njoya, Gertrude Foudjo Melacheu Laura, Jean-Bosco Jouda, Fei Wang, Céline Djama Mbazoa, Jean Wandji, Elisabeth Seguin, Brussine Nadege Wakeu Kweka

Publikováno v: Natural Product Research. 35:1590-1595

One new indole alkaloid derivative, 5,6-dioxo-11-hydroxy voacangine (1) together with four known compounds (2-5), were isolated from the fruits of Tabernaemontana inconspicua Stapf (Apocynaceae). T...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f5d74ac36ac51c9be4b1cb226dc3daf
https://doi.org/10.1080/14786419.2019.1628749

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