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An experimental strategy to probe Gq contribution to signal transduction in living cells

Autor: Patt, Julian, Alenfelder, Judith, Pfeil, Eva Marie, Voss, Jan Hendrik, Merten, Nicole, Eryilmaz, Funda, Heycke, Nina, Rick, Uli, Inoue, Asuka, Kehraus, Stefan, Deupi, Xavier, Müller, Christa E., König, Gabriele M., Crüsemann, Max, Kostenis, Evi

Publikováno v: In Journal of Biological Chemistry January-June 2021 296

Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359

Autor: Hermes, Cornelia, Richarz, René, Wirtz, Daniel A., Patt, Julian, Hanke, Wiebke, Kehraus, Stefan, Voß, Jan Hendrik, Küppers, Jim, Ohbayashi, Tsubasa, Namasivayam, Vigneshwaran, Alenfelder, Judith, Inoue, Asuka, Mergaert, Peter, Gütschow, Michael, Müller, Christa E., Kostenis, Evi, König, Gabriele M., Crüsemann, Max

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications, 2021, 12 (1), pp.144. ⟨10.1038/s41467-020-20418-3⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.144. ⟨10.1038/s41467-020-20418-3⟩

The potent and selective Gq protein inhibitor depsipeptide FR900359 (FR), originally discovered as the product of an uncultivable plant endosymbiont, is synthesized by a complex biosynthetic system comprising two nonribosomal peptide synthetase (NRPS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c7e750be03e5389994cc81c63d86217b
https://doaj.org/article/2463819dc4b944af9d1f08c6cace66cc

A Putative Frizzled 7-Targeting Compound Acts as a Firefly Luciferase Inhibitor

Autor: Kinsolving, Julia, Grätz, Lukas, Voss, Jan Hendrik, Löw, Bente, Shorter, Emily, Jude, Baptiste, Lanner, Johanna T, Löber, Stefan, Gmeiner, Peter, Schulte, Gunnar

Publikováno v: Journal of Medicinal Chemistry; 20240101, Issue: Preprints

From Garage to Grand Prix: Adaptation and Knowledge Integration in Complex Systems.

Autor: Voss, Jan Hendrik¹, Williams, Charles¹

Publikováno v: Academy of Management Annual Meeting Proceedings. 2014, Vol. 2014 Issue 1, p1-1. 1p.