Biochemical and biophysical studies to characterise the Ras:Sos:nucleotide interactions

Autor: Vo, Uybach

Ras proteins are mutated in 30% of all human tumours contributing to several malignant phenotypes including abnormal cell growth, proliferation and apoptosis. The activity of Ras is controlled by the inter-conversion between GTP- and GDP- bound forms

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706236

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H, C and N resonance assignment for the human K-Ras at physiological pH.

Autor: Vo, Uybach, Embrey, Kevin, Breeze, Alexander, Golovanov, Alexander

Publikováno v: Biomolecular NMR Assignments; Oct2013, Vol. 7 Issue 2, p215-219, 5p

¹H, ¹³C and ¹⁵N resonance assignment for the human K-Ras at physiological pH.

Autor: Vo U; Faculty of Life Sciences, Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK., Embrey KJ, Breeze AL, Golovanov AP

Publikováno v: Biomolecular NMR assignments [Biomol NMR Assign] 2013 Oct; Vol. 7 (2), pp. 215-9. Date of Electronic Publication: 2012 Aug 12.