Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Vm, Mishin"'
Publikováno v:
Europe PubMed Central
Effects of pyridine and pyridine-N-oxide on the monooxygenase system of rat liver microsomes have been studied. Pyridine (200 mg/kg) increased total cytochrome P-450 content and activated metabolism of some specific substrates 24 hours after injectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::703efbe35a229c1c9616fcafc548ba5d
https://pubmed.ncbi.nlm.nih.gov/1457601
https://pubmed.ncbi.nlm.nih.gov/1457601
Publikováno v:
Europe PubMed Central
The synthesis of pharmacologically active diazepam metabolites (oxazepam, 4-hydroxydiazepam, N-demethyldiazepam) in liver microsomes of intact and phenobarbital-, 3-methylcholanthrene- and dexamethasone-induced male and female Wistar rats as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4736374f6e682c4adb9619c2401d5e95
https://pubmed.ncbi.nlm.nih.gov/2223898
https://pubmed.ncbi.nlm.nih.gov/2223898
Publikováno v:
Europe PubMed Central
The reconstitution of microsomal membrane monooxygenase system with variable contents of the hydroxylating chain enzymatic components was carried out. It was found that during self-assembly of microsomal membranes solubilized with 4% sodium cholate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::88125aec034a80e4596ec1f95226368e
https://pubmed.ncbi.nlm.nih.gov/6428468
https://pubmed.ncbi.nlm.nih.gov/6428468
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::694f7d86b639c602df9b2f5da903efca
https://pubmed.ncbi.nlm.nih.gov/2672581
https://pubmed.ncbi.nlm.nih.gov/2672581
Publikováno v:
Europe PubMed Central
Solubilization of liver microsomes of intact, phenobarbital-treated and 3-methylcholantrene-treated rats was investigated. It was shown that treatment of microsomes with 4% sodium cholate leads to separation of proteins and phospholipids from the mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3d689539aca44a3925e6e763814f79d8
https://pubmed.ncbi.nlm.nih.gov/6830917
https://pubmed.ncbi.nlm.nih.gov/6830917
Publikováno v:
Europe PubMed Central
Changes in the metabolic activity of 7-ethoxyresorufin in rat liver microsomes containing different amounts of cytochrome P-450 induced by 3-methylcholanthrene and other polycyclic hydrocarbons (P-450c) were studied. Using antibodies to cytochrome P-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5322d70cbef88819de17236620e7a586
http://europepmc.org/abstract/med/3179354
http://europepmc.org/abstract/med/3179354
Publikováno v:
Europe PubMed Central
The effects of tetrahydrofuran (THF) on rat liver microsomes in vitro and in vivo were opposite. In vitro THF inhibited the p-nitrophenol (PNP) hydroxylase activity of microsomes from control rats and from rats treated with PB, acetone, and isoniazid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::46eda9bf8849a79b5e144a8929749741
http://europepmc.org/abstract/med/1294255
http://europepmc.org/abstract/med/1294255
Publikováno v:
Europe PubMed Central
Theophylline metabolism has been studied in a reconstituted monooxygenase system with purified forms of cytochrome P-450: P-450a, P-450b, P-450d and P-450k as well as in liver microsomes of control and 3-methylcholanthrene-induced rats. Cytochrome P-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::297a5202083bc878dfa0d6aded2fe1bd
http://europepmc.org/abstract/med/2078625
http://europepmc.org/abstract/med/2078625
Publikováno v:
Europe PubMed Central
Cytochrome P-450 forms appearing in the liver after injection of methylcholanthrene, polychlorinated biphenyls and perfluorochemical emulsion to rats were studied. Activities of marker enzymes, benzpyrenehydroxylase and 7-ethoxyresorufin-O-deethylase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::abfa1766215d4429fe48a6f5eae7b7c6
http://europepmc.org/abstract/med/2499361
http://europepmc.org/abstract/med/2499361
Publikováno v:
Europe PubMed Central
In experiments on male Wistar rats it has been found that nifedipine applied in a dose of 10 mg/kg body weight i.p. daily for 20 days did not significantly increase the total amount of cytochrome P-450 but markedly increased the 7 alpha-, 16 beta- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8f95913cf01a7ccbf1a065556fb47596
http://europepmc.org/abstract/med/2337647
http://europepmc.org/abstract/med/2337647