Výsledky vyhledávání - "Vlijmen, B.J.M. van"

Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model

Autor: Kreft, I.C., Winiarczyk, R.R.A., Tanis, F.J., Zwaan, C. van der, Schmitz, K.S., Hoogendijk, A.J., Swart, R.L. de, Moscona, A., Porotto, M., Salvatori, D.C.F., Vries, R.D. de, Maat, M.P.M. de, Biggelaar, M. van den, Vlijmen, B.J.M. van, Dutch Covid-19 Thrombosis Coaliti

Publikováno v: Thrombosis Research, 210, 6. Elsevier Ltd
Thrombosis Research: Vascular Obstruction, Hemorrhage and Hemostasis, 210, 6-11. PERGAMON-ELSEVIER SCIENCE LTD
Thrombosis Research, 210, 6-11. Elsevier Ltd.
Thrombosis Research

Background: Many patients who are diagnosed with coronavirus disease 2019 (COVID-19) suffer from venous thromboembolic complications despite the use of stringent anticoagulant prophylaxis. Studies on the exact mechanism(s) underlying thrombosis in CO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16564e61a3770959588370038f70c44
https://doi.org/10.1016/j.thromres.2021.12.015

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Assessment of breast cancer progression and metastasis during a hypercoagulable state induced by silencing of antithrombin in a xenograft mouse model

Autor: Buijs, J.T., Unlu, B., Laghmani, E.H., Heestermans, M., Vlijmen, B.J.M. van, Versteeg, H.H.

Publikováno v: Thrombosis Research: Vascular Obstruction, Hemorrhage and Hemostasis, 221, 51-57. PERGAMON-ELSEVIER SCIENCE LTD

Local coagulation activation has been shown to impact both primary tumor growth and metastasis in mice. It is well known that components of the blood clotting cascade such as tissue factor and thrombin play a role in tumor progression by activating c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a468db6e1723afad22c3f60940e992a8
http://hdl.handle.net/1887/3563151

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Correction of a dominant-negative von Willebrand factor multimerization defect by small interfering RNA-mediated allele-specific inhibition of mutant von Willebrand factor

Autor: Jong, A. de, Dirven, R.J., Oud, J.A., Tio, D., Vlijmen, B.J.M. van, Eikenboom, J.

Publikováno v: Journal of Thrombosis and Haemostasis, 16(7), 1357-1368

Background Treatment of the bleeding disorder von Willebrand disease (VWD) focuses on increasing von Willebrand factor (VWF) levels by administration of desmopressin or VWF‐containing concentrates. Both therapies leave the production of mutant VWF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dab7022e9256a6b79db129382d65a098
https://hdl.handle.net/1887/95706

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Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice

Autor: Boesten, L.S.M., Zadelaar, A.S.M., Nieuwkoop, A. van, Hu, L., Teunisse, A.F.A.S., Jochemsen, A.G., Evers, B., Water, B. van de, Gijbels, M.J.J., Vlijmen, B.J.M. van, Havekes, L.M., Winther, M.P.J. de

Publikováno v: Atherosclerosis, 2, 207, 399-404

The cellular composition of atherosclerotic lesions is determined by many factors including cell infiltration, proliferation and cell death. Tumor suppressor gene p53 has been shown to regulate both cell proliferation and cell death in many cell type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a02ca0e687e628e9d4d567a80718e10
http://resolver.tudelft.nl/uuid:2c9d2fe8-6240-4b65-9232-de00260d9a21

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The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI

Autor: Hu, L., Hoogt, C.C. van der, Espirito Santo, S.M.S., Out, R., Kypreos, K.E., Vlijmen, B.J.M. van, Berkel, T.J.C. van, Romijn, J.A., Havekes, L.M., Dijk, K.W. van, Rensen, P.C.N.

Publikováno v: Journal of Lipid Research, 7, 49, 1553-1561

LPL activity plays an important role in preceding the VLDL remnant clearance via the three major apolipoprotein E (apoE)-recognizing receptors: the LDL receptor (LDLr), LDL receptor-related protein (LRP), and VLDL receptor (VLDLr). The aim of this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5920c7b5b98bf32a9578f5d40763cc9a
http://resolver.tudelft.nl/uuid:2703c7b0-22e4-4052-952d-ce70fc8f42a8

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Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in apoE/LDLR double knockout mice

Autor: Hu, L., Boesten, L.S.M., May, P., Herz, J., Bovenschen, N., Huisman, M.V., Berbée, J.F.P., Havekes, L.M., Vlijmen, B.J.M. van, Tamsma, J.T.

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology, 12, 26, 2710-2715

OBJECTIVE - In vitro studies implicate that the low-density lipoprotein receptor (LDLR)-related protein (LRP) in macrophages has a pro-atherogenic potential. In the present study, we investigated the in vivo role of macrophage specific LRP in atherog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f287a49c0f26e3b11de57ebc93ce7a3f
http://resolver.tudelft.nl/uuid:0926cb03-bf6b-4971-834b-6b933e2b6e29

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