Glioblastomas exploit truncated O - linked glycans for local and distant immune modulation via the macrophage galactose-type lectin

Autor: Dusoswa, S.A., Verhoeff, J., Abels, E., Mendez-Huergo, S.P., Croci, D.O., Kuijper, L.H., Miguel, E. de, Wouters, V.M.C.J., Best, M.G., Rodriguez, E., Cornelissen, L.A.M., Vliet, S.J. van, Wesseling, P., Breakefield, X.O., Noske, D.P., Wurdinger, T., Broekman, M.L.D., Rabinovich, G.A., Kooyk, Y. van, Garcia-Vallejo, J.J.

Glioblastoma is the most aggressive brain malignancy, for which immunotherapy has failed to prolong survival. Glioblastoma-associated immune infiltrates are dominated by tumor-associated macrophages and microglia (TAMs), which are key mediators of im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______202::c86422fe0864ac84ed9712633ef1c6bf
https://hdl.handle.net/1887/3626991

HOW DO GLYCANS AFFECT IMMUNE CELLS IN RA?

Autor: Molhoek, A.K., Lubbers, J., Garcia-Vellejo, J.J., Vliet, S.J. van, Toes, R.E.M., Kooyk, Y. van

Publikováno v: Annals of the Rheumatic Diseases, 76(Suppl 1), A76.2-A77. BMJ Publishing Group
Annals of the Rheumatic Diseases, 76, A76-A77
Molhoek, A, Lübbers, J, Garcia Vallejo, JJ, van Vliet, SJ, Toes, R E M & van Kooyk, Y 2017, ' How do glycans affect immune cells in RA? ', Annals of the Rheumatic Diseases, vol. 76(Suppl 1), pp. A76.2-A77 . https://doi.org/10.1136/annrheumdis-2016-211055.5

Background Anti-Citrullinated Protein Antibodies (ACPAs) are specific for Rheumatoid Arthritis (RA) and have been implicated in disease pathogenesis. The fragment antigen-binding domain of ACPA was recently shown to be extensively glycosylated. It is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d6cf910ee0e4f95ff4e36ee51df9d055
https://hdl.handle.net/1887/116543

Potential Bioactivities, Chemical Composition, and Conformation Studies of Exopolysaccharide-Derived Aspergillus sp. Strain GAD7.

Autor: Ibrahim, Mohamed I. A.^1,2 (AUTHOR) drhassan1973@yahoo.com, Ibrahim, Hassan A. H.² (AUTHOR), Haga, Tatsuki¹ (AUTHOR), Ishida, Atsuhiko³ (AUTHOR) aishida@hiroshima-u.ac.jp, Nehira, Tatsuo⁴ (AUTHOR), Matsuo, Koichi^1,5,6 (AUTHOR) ibra2020@hiroshima-u.ac.jp, Gad, Ahmed M.² (AUTHOR) ibra2020@hiroshima-u.ac.jp

Publikováno v: Journal of Fungi. Sep2024, Vol. 10 Issue 9, p659. 20p.

Surface Markers and Chemokines/Cytokines of Tumor-Associated Macrophages in Osteosarcoma and Other Carcinoma Microenviornments—Contradictions and Comparisons.

Autor: Tatsuno, Rikito¹ (AUTHOR) rtatsuno@yamanashi.ac.jp, Komohara, Yoshihiro² (AUTHOR) ycomo@kumamoto-u.ac.jp, Pan, Cheng² (AUTHOR) tschpuhn@kumamoto-u.ac.jp, Kawasaki, Tomonori³ (AUTHOR) tomo.kawasaki.14@gmail.com, Enomoto, Atsushi⁴ (AUTHOR) enomoto@iar.nagoya-u.ac.jp, Jubashi, Takahiro¹ (AUTHOR) tjubashi@yamanashi.ac.jp, Kono, Hiroyuki¹ (AUTHOR) hkono@yamanashi.ac.jp, Wako, Masanori¹ (AUTHOR) wako@yamanashi.ac.jp, Ashizawa, Tomoyuki¹ (AUTHOR) tashizawa@yamanashi.ac.jp, Haro, Hirotaka¹ (AUTHOR) haro@yamanashi.ac.jp, Ichikawa, Jiro¹ (AUTHOR) jichi@sb4.so-net.ne.jp

Publikováno v: Cancers. Aug2024, Vol. 16 Issue 16, p2801. 19p.

The actin cytoskeleton regulates LFA-ligand binding through avidity rather than affinity changes

Autor: Kooyk, Y. van, Vliet, S.J. van, Figdor, C.G.

Publikováno v: Journal of Biological Chemistry, 274, 26869-26877
Journal of Biological Chemistry, 274, 38, pp. 26869-26877

Contains fulltext : 188726.pdf (Publisher’s version ) (Open Access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d8c222b79dace5ef2c04acc2167ad656
http://hdl.handle.net/2066/188726