Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vlatka Bencetić Mihaljević"'
Autor:
Ivaylo Jivkov Elenkov, Simon Feldbaek Nielsen, Kristina Butković, Sanja Koštrun, Dijana Pesic, Dack Kevin Neil, Tine Skak-Nielsen, Dinko Žiher, Martin Stahlhut, Adriana Petrinić Grba, Vlatka Bencetić Mihaljević, Ana Čikoš, Samra Kapić, Andrea Fajdetić, Renata Rupčić, Gordon Saxty, Maja Lambert, Jasna Padovan, Ivana Ozimec Landek, Karmen Brajša, Dubravko Jelić, Haakan Bladh, Ana Grgičević
Publikováno v:
Journal of Medicinal Chemistry. 64:8354-8383
Interleukin 17 (IL-17) cytokines promote inflammatory pathophysiology in many autoimmune diseases, including psoriasis, multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease. Such broad involvement of IL-17 in various autoimmune di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05f28315da0be7107038b135d157e95
https://doi.org/10.1021/acs.jmedchem.1c00327
https://doi.org/10.1021/acs.jmedchem.1c00327
Autor:
Vlatka Bencetić Mihaljević, Andrea Fajdetić, Jasna Padovan, Domingo Gargallo-Viola, Amanda Mathis, Esperanza Herreros, Mihailo Banjanac, María Santos Martínez, Radan Spaventi, Albane Kessler, Iñigo Angulo-Barturen, Mihaela Perić, Vesna Eraković Haber, Vesna Munic Kos, Santiago Ferrer-Bazaga, Sulejman Alihodžić, María Belén Jiménez-Díaz, Dijana Pesic, Francisco-Javier Gamo, Mirjana Bukvić
Publikováno v:
British journal of pharmacology. 178(2)
Background and purpose: Efficacy of current antimalarial treatments is declining as a result of increasing antimalarial drug resistance, so new and potent antimalarial drugs are urgently needed. Azithromycin, an azalide antibiotic, was found useful i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a230fcc3129988b988dd1906910df64
https://pubmed.ncbi.nlm.nih.gov/33085774
https://pubmed.ncbi.nlm.nih.gov/33085774
Autor:
Patrick C. Fraering, Jeremy Fraering, Emilie Durieu, Spiros D. Garbis, Svenja Koslowski, Josef Pannee, Laurent Meijer, Morgane Cam, Branka Tavčar, Vesna Eraković Haber, Erik Portelius, Frank Karg, Kazuo Yamamoto, Philipp Koch, Vlatka Bencetić Mihaljević, Pierrïck Auvray, Marion Bodin, Henrik Zetterberg, Patrick Gizzi, Bruce D. Hammock, Kaj Blennow, Toshiharu Suzuki, Bogdan Barnych, Hermeto Gerber, Bettina Bohl, Chiori Omori, Saori Hata, Natalia Vasylieva, Antigoni Manousopoulou
Publikováno v:
Journal of Alzheimer's disease : JAD, vol 62, iss 4
Journal of Alzheimer's Disease
Volume 62
Issue 4
Journal of Alzheimer's Disease
Volume 62
Issue 4
Generation of amyloid-β peptides (Aβs) by proteolytic cleavage of the amyloid-β protein precursor (AβPP), especially increased production of Aβ(42)/Aβ(43) over Aβ(40), and their aggregation as oligomers and plaques, represent a characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c32271f97fb48054d71da66d94c7a02
https://escholarship.org/uc/item/6357v0ng
https://escholarship.org/uc/item/6357v0ng
Autor:
Danijela Nožinić, Jasna Padovan, Astrid Milić, Vlatka Bencetić Mihaljević, Vesna Munić, Boris Mildner, Ivica Malnar, Ana Bokulić, Branka Tavčar, Jovica Ralić
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 39:263-276
The purpose of this study was to evaluate the impact of structural modifications on the 15-membered macrolactone ring and/or substituents on the in vitro ADME properties and in vivo pharmacokinetic (PK) profile for selected derivatives in rodents in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e7da16ec0e570c297682f7c2f2e9c7
https://doi.org/10.1007/s13318-013-0155-8
https://doi.org/10.1007/s13318-013-0155-8
Autor:
Vlatka Bencetić Mihaljević, Genoveva Murillo, Jasna Padovan, Sergei Tjulandin, Evgenia Gavrilova, Mikhail Byakhov, Ilya Tsimafeyeu, Nadezhda Dragun
Publikováno v:
Molecular Cancer Therapeutics. 17:B084-B084
Alofanib (RPT835) is a novel allosteric FGFR2 inhibitor with activity in FGFR2-expressing cancers. Here we explore the pharmacokinetic (PK) profile of compound. Five preclinical PK studies were conducted. In Study 1, alofanib was administered to 49 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1668c3df4b9e240db71ef33c2d00aa3b
https://doi.org/10.1158/1535-7163.targ-17-b084
https://doi.org/10.1158/1535-7163.targ-17-b084
Autor:
Sanja Koštrun, Radan Spaventi, Jasna Padovan, Sulejman Alihodžić, Branka Tavčar, Vlatka Bencetić Mihaljević, Ines Glojnarić, Berislav Bošnjak, Samra Kapić, Karmen Brajša, Ines Vujasinović, Zorica Marušić Ištuk, Martina Bosnar, Donatella Verbanac, Goran Kragol, Vesna Eraković Haber, Dubravko Jelić, Ognjen Čulić, Boska Hrvacic
Macrolide antibiotics, like erythromycin, clarithromycin, and azithromycin, possess anti- inflammatory properties. These properties are considered fundamental to the efficacy of these three macrolides in the treatment of chronic inflammatory diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3458887a3e190972fde3017587fd61b
https://www.bib.irb.hr/721681
https://www.bib.irb.hr/721681
Autor:
Jasna Padovan, Mikhail Byakhov, Ilya Tsimafeyeu, Sergei Tjulandin, Vlatka Bencetić Mihaljević, Genoveva Murillo
Publikováno v:
Molecular Cancer Therapeutics. 14:B146-B146
RPT835 (recommended INN, alofanib) is a novel allosteric FGFR2 inhibitor with activity in FGFR2-expressing women's cancers. Administration of RPT835 intravenously (iv) daily demonstrated dramatic effect in ovarian cancer xenografts compared with RPT8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f62052233eea9c6c6431744fb129e2c2
https://doi.org/10.1158/1535-7163.targ-15-b146
https://doi.org/10.1158/1535-7163.targ-15-b146
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 37(3)
The aim of this study was to compare the roles of gastrointestinal absorption and hepatic extraction as barriers to oral bioavailability for macrolide antibiotics erythromycin, clarithromycin, roxithromycin and telithromycin. In this study, the in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fedfa2bbdd23dded745ba57a6d16ee
https://pubmed.ncbi.nlm.nih.gov/22113743
https://pubmed.ncbi.nlm.nih.gov/22113743
Autor:
Jovica Ralić, Ivica Malnar, V. Sunjic, Anita Filipović Sučić, Andreja Čempuh Klonkay, Snježana Dragojević, Ivaylo Jivkov Elenkov, Vesna Gabelica-Marković, Marina Ilijaš, Milan Mesic, Vlatka Bencetić-Mihaljević, Lidija Lerman
The stability in aqueous solution of five classes of coumarin dimers (I–V, compounds 1–29) was studied by HPLC–MS/MS at various pH values. The relationship between chemical structure and stability is discussed. It was found that dimeric compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b307b5b0f1bcfaf6fc62b96c6c472c
https://doi.org/10.1016/j.jpba.2010.08.002
https://doi.org/10.1016/j.jpba.2010.08.002