Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vlatka Antolović"'
Autor:
John ME Nichols, Vlatka Antolović, Jacob D Reich, Sophie Brameyer, Peggy Paschke, Jonathan R Chubb
Publikováno v:
eLife, Vol 9 (2020)
Dedifferentiation is a critical response to tissue damage, yet is not well understood, even at a basic phenomenological level. Developing Dictyostelium cells undergo highly efficient dedifferentiation, completed by most cells within 24 hr. We use thi
Externí odkaz:
https://doaj.org/article/7cab134f6343447b90b5ebf49ea698a8
Development can proceed in “fits and starts”, with rapid transitions between cell states involving concerted transcriptome-wide changes in gene expression. However, it is not clear how these transitions are regulated in complex cell populations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f5f6e92f961f57d8afc180303a99fb
https://doi.org/10.1101/2023.05.03.539233
https://doi.org/10.1101/2023.05.03.539233
Publikováno v:
Developmental Cell. 56:2142-2144
A persistent view of cell fate choices during development entails centralized control by so-called master regulators. A recent single-cell study of the large-scale fate specification during mammalian gastrulation (Mittnenzweig et al., 2021) implies t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f975b2e37b5531ed789035489e85708b
https://doi.org/10.1016/j.devcel.2021.07.007
https://doi.org/10.1016/j.devcel.2021.07.007
Autor:
Peggy Paschke, Jonathan R. Chubb, John M.E. Nichols, Sophie Brameyer, Jacob D Reich, Vlatka Antolović
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Dedifferentiation is a critical response to tissue damage, yet is not well understood, even at a basic phenomenological level. Developing Dictyostelium cells undergo highly efficient dedifferentiation, completed by most cells within 24 hr. We use thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2956db9d76a5fd71c44a62642655758
https://doi.org/10.7554/elife.55435
https://doi.org/10.7554/elife.55435
Publikováno v:
Deathridge, J, Antolović, V, Parsons, M & Chubb, J R 2019, ' Live imaging of erk signalling dynamics in differentiating mouse embryonic stem cells ', Development (Cambridge), vol. 146, no. 12, dev172940 . https://doi.org/10.1242/dev.172940
Stimulation of the ERK/MAPK pathway is required for the exit from pluripotency and onset of differentiation in mouse embryonic stem cells (ESCs). The dynamic behavior of ERK activity in individual cells during this transition is unclear. Using a FRET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dba54dc4bcf990d857c42d0491fe158
https://kclpure.kcl.ac.uk/en/publications/fbf6da2f-c9d9-45af-b639-0e717efc3e24
https://kclpure.kcl.ac.uk/en/publications/fbf6da2f-c9d9-45af-b639-0e717efc3e24
Autor:
Vlatka Antolović, Agnes Miermont, Jonathan R. Chubb, Tchern Lenn, Lindsey J. Millward, John M.E. Nichols
Publikováno v:
Development.
Embryonic development involves extensive and often rapid cell proliferation. An unavoidable side effect of cell proliferation is DNA damage. The consequences of spontaneous DNA damage during development are not clear. Here we define an approach to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23ed644411e6da7576182a40a8e8e72
https://doi.org/10.1242/dev.174268
https://doi.org/10.1242/dev.174268
Publikováno v:
Development.
The generation of multiple fates from a uniform cell population via self-organisation is a recurring feature in development and regeneration. However, for most self-organising systems, we have little understanding of the processes that allow cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aff26a08cbb009df16a1cdf4993204e
https://doi.org/10.1242/dev.173740
https://doi.org/10.1242/dev.173740
Publikováno v:
Histochemistry and cell biology. 146(3)
Small Rho GTPases are major regulators of the actin cytoskeleton dynamics in eukaryotic cells. Sophisticated tools used to investigate their activity in living cells include probes based on fluorescence resonance energy transfer (FRET), bimolecular f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fd40558e70907c73aceaa042224cfd
https://pubmed.ncbi.nlm.nih.gov/27126594
https://pubmed.ncbi.nlm.nih.gov/27126594
Publikováno v:
Journal of Microbiological Methods. 104:9-11
We describe a simple optical configuration for dark-field microscopy at low magnification, realized with the use of standard microscope components. An inherent high contrast makes this method attractive for computer-assisted tracking and counting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc106730dbea1db3b50f4fe56b07644c
https://doi.org/10.1016/j.mimet.2014.06.006
https://doi.org/10.1016/j.mimet.2014.06.006