Výsledky vyhledávání - "Vlahopoulos, S."

Aldehyde Dehydrogenase Enzyme Functions in Acute Leukemia Stem Cells

Autor: Dancik, G.M. Voutsas, I.F. Vlahopoulos, S.

The enzymes that belong to the aldehyde dehydrogenase family are expressed in a variety of cells; yet activity of their main members characterizes stem cells, both normal and malignant. Several members of this family perform critical functions in ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::d5cfe21bf7ddb617b97826098e133209
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3220587

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Early and Very Early GRIM19 and MCL1 Expression Are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line

Autor: G, L. Adamaki, M. Hatziagapiou, K. Geronikolou, S.A. Tsartsalis, A.N. Vlahopoulos, S.

Glucocorticoids (GCs) are still first-line drugs for the treatment of childhood acute lymphoblastic leukemia (ALL). Prednisolone is a corticosteroid and one of the most important agents in the treatment of ALL. We report here a study of Prednisolone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::2490fb2babca997905b30aebf7c43c5d
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077218

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Dual mechanisms of metabolism and gene expression of the ccrf-cem leukemia cells under glucocorticoid treatment

Autor: Lambrou, G.I. Karakonstantakis, T. Vlahopoulos, S. Zaravinos, A.

Background: Glucocorticoids play an essential part in anti-leukemic therapies, but resistance is a crucial event for the prognosis of the disease. Glucocorticoids influence the metabolic properties of leukemic cells. The inherent plasticity of clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::e48371bed5bfac2602342c90865766a3
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2980782

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Gene expression and resistance to glucocorticoid-induced apoptosis in acute lymphoblastic leukemia: A brief review and update

Autor: Lambrou, G.I. Adamaki, M. Hatziagapiou, K. Vlahopoulos, S.

Background: Resistance to glucocorticoid (GC)-induced apoptosis in Acute Lympho-blastic Leukemia (ALL), is considered one of the major prognostic factors for the disease. Predniso-lone is a corticosteroid and one of the most important agents in the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::7b76443e77e454123acda86cfd863c1f
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3121587

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Dissecting pharmacological effects of chloroquine in cancer treatment: interference with inflammatory signaling pathways

Autor: Varisli, L. Cen, O. Vlahopoulos, S.

Chloroquines are 4-aminoquinoline-based drugs mainly used to treat malaria. At pharmacological concentrations, they have significant effects on tissue homeostasis, targeting diverse signaling pathways in mammalian cells. A key target pathway is autop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::f79870fc43a87ea9ec07c154321a48ca
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3000257

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Inflammation and tissue homeostasis: the NF-κB system in physiology and malignant progression

Autor: Lambrou, G.I. Hatziagapiou, K. Vlahopoulos, S.

Disruption of tissue function activates cellular stress which triggers a number of mechanisms that protect the tissue from further damage. These mechanisms involve a number of homeostatic modules, which are regulated at the level of gene expression b

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https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3078061

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Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer

Autor: Vlahopoulos, S. Adamaki, M. Khoury, N. Zoumpourlis, V. Boldogh, I.

Cytokines are pivotal mediators of the immune response, and their coordinated expression protects host tissue from excessive damage and oxidant stress. Nevertheless, the development of lung pathology, including asthma, chronic obstructive pulmonary d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::416e9b339fa11ba920c28ca195deae2c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3021384

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Serum irisin concentrations in lean adolescents with polycystic ovary syndrome

Autor: Bacopoulou, F. Athanasopoulos, N. Efthymiou, V. Mantzou, A. Aravantinos, L. Vlahopoulos, S. Deligeoroglou, E.

Objective: To explore differences in irisin concentrations between lean adolescents with PCOS and age- and body mass index (BMI)-matched controls and examine the associations of irisin with core features of the syndrome. Design: Cross-sectional study

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https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086969

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Aberrant AML1 gene expression in the diagnosis of childhood leukemias not characterized by AML1-involved cytogenetic abnormalities

Autor: Adamaki, M. Vlahopoulos, S. Lambrou, G.I. Papavassiliou, A.G. Moschovi, M.

The AML1 (acute myeloid leukemia 1) gene, a necessary prerequisite of embryonic hematopoiesis and a critical regulator of normal hematopoietic development, is one of the most frequently mutated genes in human leukemia, involving over 50 chromosome tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::3fa569f9b784312c208717cbfa8894cf
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3087188

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