Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vladyslava Liudkovska"'
Autor:
Seweryn Mroczek, Justyna Chlebowska, Tomasz M. Kuliński, Olga Gewartowska, Jakub Gruchota, Dominik Cysewski, Vladyslava Liudkovska, Ewa Borsuk, Dominika Nowis, Andrzej Dziembowski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
FAM46C is one of the most frequently mutated genes in multiple myeloma (MM), but its molecular function remains unknown. Here the authors show that FAM46C is a poly(A) polymerase and that loss of function of FAM46C drives multiple myeloma through the
Externí odkaz:
https://doaj.org/article/2729a3c633ac4d3d9be13d21bf41dfa0
Autor:
Tetiana V Bondarchuk, Vyacheslav F Shalak, Dmytro M Lozhko, Agnieszka Fatalska, Roman H Szczepanowski, Vladyslava Liudkovska, Oleksandr Yu Tsuvariev, Michal Dadlez, Anna V El'skaya, Boris S Negrutskii
Publikováno v:
Nucleic acids research. 50(16)
Protein synthesis in eukaryotic cell is spatially and structurally compartmentalized that ensures high efficiency of this process. One of the distinctive features of higher eukaryotes is the existence of stable multi-protein complexes of aminoacyl-tR
Autor:
Marek Tchórzewski, Lidia Borkiewicz, Leszek Wawiórka, Joanna Kufel, Vladyslava Liudkovska, Monika Szajwaj, Barbara Michalec-Wawiórka, Eliza Molestak, Aleksandra Boguszewska
The ribosomal GTPase associated center constitutes the ribosomal area, which is the landing platform for translational GTPases and stimulates their hydrolytic activity. The ribosomal stalk represents a landmark structure in this center, and in eukary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8100f9d6e87438d2ec3998737755eeb
https://europepmc.org/articles/PMC4889275/
https://europepmc.org/articles/PMC4889275/
Autor:
Vladyslava Liudkovska, Andrzej Dziembowski, Seweryn Mroczek, Olga Gewartowska, Zbigniew Warkocki
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
In eukaryotes, almost all RNA species are processed at their 3′ ends and most mRNAs are polyadenylated in the nucleus by canonical poly(A) polymerases. In recent years, several terminal nucleotidyl transferases (TENTs) including non-canonical poly(
Autor:
Tomasz M. Kulinski, Ewa Borsuk, Vladyslava Liudkovska, Dominika Nowis, Andrzej Dziembowski, Jakub Gruchota, Olga Gewartowska, Seweryn Mroczek, Dominik Cysewski, Justyna Chlebowska
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications
FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene
Publikováno v:
Wiley Interdisciplinary Reviews: RNA
Wiley Interdisciplinary Reviews. RNA
Wiley Interdisciplinary Reviews. RNA
Termini often determine the fate of RNA molecules. In recent years, 3′ ends of almost all classes of RNA species have been shown to acquire nontemplated nucleotides that are added by terminal nucleotidyltransferases (TENTs). The best‐described ro