Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Vladyslav V, Vyazovskiy"'
Autor:
Atreyi Chakrabarty, Sarah E. Newey, Maisha M. Promi, Belinda K. Agbetiameh, Daniella Munro, Paul J. N. Brodersen, Gemma Gothard, Kashif Mahfooz, Jose P. Mengual, Vladyslav V. Vyazovskiy, Colin J. Akerman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The unfolded protein response (UPR) maintains proteostasis upon endoplasmic reticulum (ER) stress, and is initiated by a range of physiological and pathological processes. While there have been advances in developing fluorescent reporters fo
Externí odkaz:
https://doaj.org/article/611d39d613c2435f861b6b58e3b6b82c
Autor:
Paul J N Brodersen, Hannah Alfonsa, Lukas B Krone, Cristina Blanco-Duque, Angus S Fisk, Sarah J Flaherty, Mathilde C C Guillaumin, Yi-Ge Huang, Martin C Kahn, Laura E McKillop, Linus Milinski, Lewis Taylor, Christopher W Thomas, Tomoko Yamagata, Russell G Foster, Vladyslav V Vyazovskiy, Colin J Akerman
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011793 (2024)
Electrophysiological recordings from freely behaving animals are a widespread and powerful mode of investigation in sleep research. These recordings generate large amounts of data that require sleep stage annotation (polysomnography), in which the da
Externí odkaz:
https://doaj.org/article/263fc5b386b345fe8fa91bf2ca6d9607
Autor:
Christian D. Harding, Mathilde C. C. Guillaumin, Lukas B. Krone, Martin C. Kahn, Cristina Blanco-Duque, Christian Mikutta, Vladyslav V. Vyazovskiy
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background During non-rapid eye movement sleep (NREM), alternating periods of synchronised high (ON period) and low (OFF period) neuronal activity are associated with high amplitude delta band (0.5–4 Hz) oscillations in neocortical electro
Externí odkaz:
https://doaj.org/article/6121f34efe00490cb98f16bfcb8ded55
Autor:
Janine Traut, Jose Prius Mengual, Elise J Meijer, Laura E McKillop, Hannah Alfonsa, Anna Hoerder-Suabedissen, Seo Ho Song, Kristoffer D Fehér, Dieter Riemann, Zoltan Molnar, Colin J Akerman, Vladyslav V Vyazovskiy, Lukas B Krone
Publikováno v:
eLife, Vol 12 (2023)
Designer receptors exclusively activated by designer drugs (DREADDs) are chemogenetic tools for remote control of targeted cell populations using chemical actuators that bind to modified receptors. Despite the popularity of DREADDs in neuroscience an
Externí odkaz:
https://doaj.org/article/d166fb9d43354de09030346fe67946c3
Autor:
Christopher W. Thomas, Cristina Blanco-Duque, Benjamin J. Bréant, Guy M. Goodwin, Trevor Sharp, David M. Bannerman, Vladyslav V. Vyazovskiy
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Serotonergic psychedelic drugs, such as psilocin (4-hydroxy-N,N-dimethyltryptamine), profoundly alter the quality of consciousness through mechanisms which are incompletely understood. Growing evidence suggests that a single psychedelic expe
Externí odkaz:
https://doaj.org/article/6caaa8a3ea294d27b106c6c2d4ac8afc
Autor:
Gauri Ang, Laurence A. Brown, Shu K. E. Tam, Kay E. Davies, Russell G. Foster, Paul J. Harrison, Rolf Sprengel, Vladyslav V. Vyazovskiy, Peter L. Oliver, David M. Bannerman, Stuart N. Peirson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Dysfunction of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1 subunit and deficits in synaptic plasticity are implicated in schizophrenia and sleep and circadian rhythm disruption. To investigate th
Externí odkaz:
https://doaj.org/article/db96924aa90f4475ae84a2e870b1ccac
Autor:
Linus Milinski, Simon P. Fisher, Nanyi Cui, Laura E. McKillop, Cristina Blanco-Duque, Gauri Ang, Tomoko Yamagata, David M. Bannerman, Vladyslav V. Vyazovskiy
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Homeostatic regulation of sleep is reflected in the maintenance of a daily balance between sleep and wakefulness. Although numerous internal and external factors can influence sleep, it is unclear whether and to what extent the pr
Externí odkaz:
https://doaj.org/article/dc6a612dba99435da68acfbd495fabb2
Autor:
Monica Gagliano, Vladyslav V Vyazovskiy, Alexander A Borbély, Martial Depczynski, Ben Radford
Publikováno v:
eLife, Vol 9 (2020)
In 2016 we reported evidence for associative learning in plants (Gagliano et al., 2016). In view of the far-reaching implications of this finding we welcome the attempt made by Markel to replicate our study (Markel, 2020). However, as we discuss here
Externí odkaz:
https://doaj.org/article/3f73b0d6e5c34afc8f6830c1073bd9a9
Autor:
Christopher W Thomas, Mathilde CC Guillaumin, Laura E McKillop, Peter Achermann, Vladyslav V Vyazovskiy
Publikováno v:
eLife, Vol 9 (2020)
Sleep homeostasis manifests as a relative constancy of its daily amount and intensity. Theoretical descriptions define ‘Process S’, a variable with dynamics dependent on global sleep-wake history, and reflected in electroencephalogram (EEG) slow
Externí odkaz:
https://doaj.org/article/b3490da4a6d44d0a9b7166724cf3a661
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Circadian rhythms and sleep-wake history determine sleep duration and intensity, and influence subsequent waking. Previous studies have shown that T cycles - light-dark (LD) cycles differing from 24 h - lead to acute changes in the daily amo
Externí odkaz:
https://doaj.org/article/1b3178f8f0a94faa85a910285df92d3d