Three years of growth hormone therapy in children born small for gestational age: results from the ANSWER Program

Autor: Robert Rapaport, Peter A Lee, Judith L Ross, Paul Saenger, Vlady Ostrow, Giuseppe Piccoli

Publikováno v: Endocrine Connections, Vol 7, Iss 10, Pp 1096-1104 (2018)

Growth hormone (GH) is used to treat short stature and growth failure associated with growth disorders. Birth size and GH status variably modulate response to GH therapy. The aim of this study was to determine the effect of birth size on response to

Externí odkaz: https://doaj.org/article/25e8a72f60974241aa462ac2a4decc17

Height outcomes in children with growth hormone deficiency and idiopathic short stature treated concomitantly with growth hormone and aromatase inhibitor therapy: data from the ANSWER program

Autor: Bradley S. Miller, Judith L. Ross, Vlady Ostrow

Publikováno v: International Journal of Pediatric Endocrinology, Vol 2020, Iss 1, Pp 1-6 (2020)
International Journal of Pediatric Endocrinology

BackgroundTreatment of children with growth hormone deficiency (GHD) or idiopathic short stature (ISS) using GH is only effective for bone growth prior to epiphyseal fusion. Aromatase inhibitor therapy (AIT) blocks estrogen production, thereby delayi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e341e0cb49776deabf2964fe88bd6551
http://link.springer.com/article/10.1186/s13633-020-00089-z

Treatment of Children With GH in the United States and Europe: Long-Term Follow-Up From NordiNet® IOS and ANSWER Program

Autor: Philippe Backeljauw, Tilman R Rohrer, Jo Blair, Michel Polak, Bradley S. Miller, Alberto Pietropoli, Judith L. Ross, Lars Sävendahl, Vlady Ostrow

Publikováno v: The Journal of Clinical Endocrinology and Metabolism

Context Understanding real-world prescribing of GH may help improve treatment of eligible patients. Objective Overall: to assess real-world effectiveness and safety of GH (Norditropin). This analysis: to compare clinical characteristics of GH-treated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624eb7b40223952528862adab0e53b74
https://doi.org/10.1210/jc.2019-00775

Sensitivity and specificity of the macimorelin test for diagnosis of AGHD

Autor: Vera Popovic, Jose M. Garcia, Nicola Ammer, Christina Wang, Ronald S. Swerdloff, Frank Strobl, Fredric J. Cohen, Rosa Rosanna Fleming, Vlady Ostrow, Márta Korbonits, Beverly M. K. Biller, Kevin C J Yuen, Gilbert Mueller, Philippe Chanson, Christian J. Strasburger, Nicky Kelepouris, Anton Luger

Publikováno v: Endocrine Connections
Endocrine Connections, Vol 10, Iss 1, Pp 76-83 (2021)

Objective The macimorelin test is approved for the diagnosis of adult growth hormone deficiency (AGHD) based on its efficacy vs the insulin tolerance test (ITT). Macimorelin has a significant advantage over ITT in avoiding hypoglycemia. Analyses were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9decc92a93ed8f8b3cf8c075a573ea
https://pubmed.ncbi.nlm.nih.gov/33320108

Growth hormone replacement in adults:Real-world data from two large studies in US and Europe

Autor: Beverly M. K. Biller, Vera Popovic-Brkic, Gediminas Puras, Mark E. Molitch, Murray B. Gordon, Natalia Holot, Charlotte Höybye, Jens Otto Lunde Jørgensen, Vlady Ostrow, Matthias M. Weber, Alberto Pietropoli

Publikováno v: Weber, M M, Gordon, M B, Höybye, C, Jørgensen, J O L, Puras, G, Popovic-Brkic, V, Molitch, M E, Ostrow, V, Holot, N, Pietropoli, A & Biller, B M K 2020, ' Growth hormone replacement in adults : Real-world data from two large studies in US and Europe ', Growth Hormone and IGF Research, vol. 50, pp. 71-82 . https://doi.org/10.1016/j.ghir.2019.09.002

Objective: This report describes the effectiveness and safety of growth hormone replacement in 3180 adult patients with growth hormone deficiency followed-up for 0.0–12.2 years in two completed, complementary, non-interventional, multicentre studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23719db8600c573c81d9c3232ef64a61
https://pure.au.dk/portal/da/publications/growth-hormone-replacement-in-adults(0a7d8646-6069-4124-ada7-f0734df606ae).html