Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Vladislav Yu. Orekhov"'
Autor:
Tatiana Agback, Dmitry Lesovoy, Xiao Han, Alexander Lomzov, Renhua Sun, Tatyana Sandalova, Vladislav Yu. Orekhov, Adnane Achour, Peter Agback
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The dengue protease NS2B/NS3pro has been reported to adopt either an ‘open’ or a ‘closed’ conformation. We have developed a conformational filter that combines NMR with MD simulations to identify conformational ensembles that dominat
Externí odkaz:
https://doaj.org/article/0d1dcdf25f9d4b78ade9adb69f7c9149
Autor:
Xiao Han, Maria Levkovets, Dmitry Lesovoy, Renhua Sun, Johan Wallerstein, Tatyana Sandalova, Tatiana Agback, Adnane Achour, Peter Agback, Vladislav Yu. Orekhov
Publikováno v:
Biomolecular NMR Assignments. 16:363-371
Mucosa-associated lymphoid tissue protein 1 (MALT1) plays a key role in adaptive immune responses by modulating specific intracellular signalling pathways that control the development and proliferation of both T and B cells. Dysfunction of these path
Autor:
Oriol Marimon, João M. C. Teixeira, Tiago N. Cordeiro, Valerie W. C. Soo, Thammajun L. Wood, Maxim Mayzel, Irene Amata, Jesús García, Ainara Morera, Marina Gay, Marta Vilaseca, Vladislav Yu Orekhov, Thomas K. Wood, Miquel Pons
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Classical toxin–antitoxin systems in bacteria are based on silencing of a toxin by an antitoxin that, when inactivated, releases the toxin, resulting in a change in metabolism. Here, the authors characterize an oxygen-sensitive toxin–antitoxin sy
Externí odkaz:
https://doaj.org/article/2b615b45d9b44155a5b1b341a0b019b8
Autor:
Peter Agback, Dmitry M. Lesovoy, Xiao Han, Renhua Sun, Tatyana Sandalova, Tatiana Agback, Adnane Achour, Vladislav Yu. Orekhov
Publikováno v:
Biomolecular NMR Assignments. 16:135-145
The serotype II Dengue (DENV 2) virus is the most prevalent of all four known serotypes. Herein, we present nearly complete 1H, 15N, and 13C backbone and 1H, 13C isoleucine, valine, and leucine methyl resonance assignment of the apo S135A catalytical
Autor:
Wolfgang Bermel, Eduard V. Bocharov, Vladislav Yu. Orekhov, Björn M. Burmann, Irena Matečko-Burmann, Panagiota S. Georgoulia, Dmitry M. Lesovoy, Tammo Diercks
Publikováno v:
Angewandte Chemie (International Ed. in English)
Dysregulation of post‐translational modifications (PTMs) like phosphorylation is often involved in disease. NMR may elucidate exact loci and time courses of PTMs at atomic resolution and near‐physiological conditions but requires signal assignmen
Autor:
Xiao Han, Maria Levkovets, Dmitry Lesovoy, Renhua Sun, Johan Wallerstein, Tatyana Sandalova, Tatiana Agback, Adnane Achour, Peter Agback, Vladislav Yu. Orekhov
Mucosa-associated lymphoid tissue protein 1 (MALT1) plays a key role in adaptive immune responses by modulating specific intracellular signalling pathways that control the development and proliferation of both T and B cells. Dysfunction of these path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4e4934dc5c6dd16f5b5f0785ea72a05
https://doi.org/10.21203/rs.3.rs-1820939/v1
https://doi.org/10.21203/rs.3.rs-1820939/v1
Autor:
Maxim Mayzel, B. Göran Karlsson, Ulrika Brath, Linnéa Isaksson, Cecilia Persson, Vladislav Yu. Orekhov, Janne A. Ihalainen, Sebastian Westenhoff, Lidija Vrhovac, Emil Gustavsson
Publikováno v:
Biophys J
Phytochromes sense red/far-red light and control many biological processes in plants, fungi, and bacteria. Although crystal structures of dark and light adapted states have been determined, the molecular mechanisms underlying photoactivation remains
Autor:
Vladislav Yu. Orekhov, Tetyana Lukash, Yulia Pustovalova, Francisco Dominguez, Peter Agback, Nikita Shiliaev, Tatiana Agback, Elena I. Frolova, Ilya Frolov
Publikováno v:
Virology
Alphavirus nsP3 proteins contains long, intrinsically disordered, hypervariable domains, HVD, which serve as hubs for interaction with many cellular proteins. Here, we have deciphered the mechanism and function of HVD interaction with host factors in
Autor:
Emad Tajkhorshid, Eduard Puig, Sonia Ciudad, Thomas Botzanowski, Mariam Bayoumi, Vladislav Yu. Orekhov, Benjamin Bardiaux, Giovanni Maglia, Sarah Cianférani, Andres S. Arango, Stéphane Chaignepain, Jimmy Do, Moeen Meigooni, Natàlia Carulla, Maxim Mayzel
Publikováno v:
Nature Communications, 11(1):3014. Nature Publishing Group
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimerʼs disease (AD). Here, we present the three-dimensional structure of an Aβ oligomer formed in a membrane mimicking envi
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68567 (2013)
Adequate digital resolution and signal sensitivity are two critical factors for protein structure determinations by solution NMR spectroscopy. The prime objective for obtaining high digital resolution is to resolve peak overlap, especially in NOESY s
Externí odkaz:
https://doaj.org/article/0c1ee625418e4504b8ed02c17e97ec2e