Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Vladislav V. Nesterenko"'
Autor:
Dan Ye, Todd J. Herron, Ryan P. O'Connell, Michael J. Ackerman, Silvia Castelletti, Maria Christina Kotta, Charles Antzelevitch, Lia Crotti, Guadalupe Guerrero-Serna, Andre Monteiro da Rocha, Margherita Torchio, Hassan Hussein Musa, Justus M.B. Anumonwo, Michael A. Makara, Peter J. Mohler, Brad Rosinski, Cherisse A. Marcou, Vladislav V. Nesterenko, Michelle L. Milstein, David J. Tester, Federica Dagradi, Peter J. Schwartz
Publikováno v:
Am J Physiol Heart Circ Physiol
Synapse-associated protein 97 (SAP97) is a scaffolding protein crucial for the functional expression of several cardiac ion channels and therefore proper cardiac excitability. Alterations in the functional expression of SAP97 can modify the ionic cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7367f1cbcd25398921636223a2e5f2
https://doi.org/10.1152/ajpheart.00481.2019
https://doi.org/10.1152/ajpheart.00481.2019
Autor:
Michael Xavier Doss, José M Di Diego, Robert J Goodrow, Yuesheng Wu, Jonathan M Cordeiro, Vladislav V Nesterenko, Héctor Barajas-Martínez, Dan Hu, Janire Urrutia, Mayurika Desai, Jacqueline A Treat, Agapios Sachinidis, Charles Antzelevitch
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40288 (2012)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold promise for therapeutic applications. To serve these functions, the hiPSC-CM must recapitulate the electrophysiologic properties of native adult cardiomyocytes. This study exa
Externí odkaz:
https://doaj.org/article/37d1fac9f03c47c1950714ea3f4d6f80
Autor:
Stephanie M. Ware, Richard J. Czosek, Charles Antzelevitch, Dan Ye, Michael J. Ackerman, Nicole J. Boczek, Vladislav V. Nesterenko, Erin M. Miller, David J. Tester
Publikováno v:
Heart Rhythm. 12:211-219
Background Timothy syndrome (TS) is a rare multisystem genetic disorder characterized by a myriad of abnormalities, including QT prolongation, syndactyly, and neurologic symptoms. The predominant genetic causes are recurrent de novo missense mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805e7f836e19699230c24f851eb7abb7
https://doi.org/10.1016/j.hrthm.2014.09.051
https://doi.org/10.1016/j.hrthm.2014.09.051
Autor:
Jonathan M. Cordeiro, Vladislav V. Nesterenko, Brian K. Panama, Mayurika Desai, Suveer Desai, Jacqueline A. Treat, Robert J. Goodrow
Publikováno v:
Journal of pharmacological and toxicological methods. 90
Introduction Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are used for safety pharmacology and to investigate genetic diseases affecting cardiac ion channels. It is unclear whether adult myocytes or hiPSC-CMs are the better
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5da35c7987b7551c1cb02e2fbab81a
https://pubmed.ncbi.nlm.nih.gov/29128504
https://pubmed.ncbi.nlm.nih.gov/29128504
Autor:
Brian K. Panama, Jonathan M. Cordeiro, Robert J. Goodrow, Jacqueline A. Treat, Lini M. Thomas, Vladislav V. Nesterenko, Tanya Zeina
Publikováno v:
Biophysical Journal. 108(2)
Background: The inward rectifier potassium current, IK1, regulates the terminal phase of repolarization of the action potential, as well as the resting membrane potential. Regional variation in IK1 has been noted in the canine heart, but the biophysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904a8c199faf7c0a37a896290e82c179
Publikováno v:
Cardiovascular Research. 63:635-644
Background: The cellular basis for the monophasic action potential (MAP) has long been a matter of debate. At the center of the controversy is the issue as to which of the two electrodes is the recording electrode and which is the indifferent electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783e428fffb7f4193618716855254f5b
https://doi.org/10.1016/j.cardiores.2004.05.003
https://doi.org/10.1016/j.cardiores.2004.05.003
Publikováno v:
Circulation. 109:2136-2142
Background— Epicardial pacing of the left ventricle (LV) has been shown to prolong the QT interval and predispose to the development of torsade de pointes arrhythmias. The present study examines the cellular basis for QT prolongation and arrhythmog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff318c411fe36315254a66a52ec792d
https://doi.org/10.1161/01.cir.0000127423.75608.a4
https://doi.org/10.1161/01.cir.0000127423.75608.a4
Publikováno v:
Circulation. Arrhythmia and electrophysiology. 7(1)
Background— Hypothermia has been reported to induce ventricular tachycardia and fibrillation (VT/VF) in patients with early repolarization (ER) pattern. This study examines the cellular mechanisms underlying VT/VF associated with hypothermia in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0462cd82e84bfeaf54220f619453af2d
https://pubmed.ncbi.nlm.nih.gov/24429494
https://pubmed.ncbi.nlm.nih.gov/24429494
Autor:
Vladislav V. Nesterenko, Charles Antzelevitch, Adam L. Muzikant, Thomas J. Colatsky, John Jeremy Rice, Gang Chen
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences. 359:1201-1216
Ventricular myocardium comprises at least three electrophysiologically distinct cell types: epicardial, endocardial and M cells. Epicardial and M cells, but not endocardial cells, display action potentials with a notched or spike–and–dome morphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb123681508d23e1e3914e1bf6cd336b
https://doi.org/10.1098/rsta.2001.0826
https://doi.org/10.1098/rsta.2001.0826
Autor:
Charles Antzelevitch, Dmitri V. Nesterenko, Pedro Brugada, Robert Dumaine, Vladislav V. Nesterenko, Jeffrey A. Towbin, Ramon Brugada, Matteo Vatta, Josep Brugada
Publikováno v:
Scopus-Elsevier
Abstract —The Brugada syndrome is a major cause of sudden death, particularly among young men of Southeast Asian and Japanese origin. The syndrome is characterized electrocardiographically by an ST-segment elevation in V1 through V3 and a rapid pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0619acae79bfa31b4a6ff6aebe29dae2
https://doi.org/10.1161/01.res.85.9.803
https://doi.org/10.1161/01.res.85.9.803