Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Vladislav G. Starkov"'
Autor:
Alexey V. Osipov, Elena G. Cheremnykh, Rustam H. Ziganshin, Vladislav G. Starkov, Trang Thuy Thi Nguyen, Khoa Cuu Nguyen, Dung Tien Le, Anh Ngoc Hoang, Victor I. Tsetlin, Yuri N. Utkin
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1115 (2023)
Protozoal infections are a world-wide problem. The toxicity and somewhat low effectiveness of the existing drugs require the search for new ways of protozoa suppression. Snake venom contains structurally diverse components manifesting antiprotozoal a
Externí odkaz:
https://doaj.org/article/7a177c847780467ab6b7d0f85c76a908
Autor:
Alexey S. Averin, Mikhail V. Goltyaev, Tatyana V. Andreeva, Vladislav G. Starkov, Victor I. Tsetlin, Yuri N. Utkin
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 28 (2022)
Abstract Background: The cardiovascular system is one of the first systems to be affected by snake toxins; but not many toxins exert a direct effect on the heart. Cobra venom cardiotoxins are among those few toxins that attack the heart. Although the
Externí odkaz:
https://doaj.org/article/0c4ab6941d1a4a2297d3eac6f46ecb5b
Autor:
Peter V. Dubovskii, Anastasia A. Ignatova, Anna S. Alekseeva, Vladislav G. Starkov, Ivan A. Boldyrev, Alexey V. Feofanov, Yuri N. Utkin
Publikováno v:
Toxins, Vol 15, Iss 1, p 6 (2022)
In aqueous solutions, cobra cytotoxins (CTX), three-finger folded proteins, exhibit conformational equilibrium between conformers with either cis or trans peptide bonds in the N-terminal loop (loop-I). The equilibrium is shifted to the cis form in to
Externí odkaz:
https://doaj.org/article/e5bc9fea67aa413bbaee97dbd23a3a0f
Autor:
Peter V. Dubovskii, Kira M. Dubova, Gleb Bourenkov, Vladislav G. Starkov, Anastasia G. Konshina, Roman G. Efremov, Yuri N. Utkin, Valeriya R. Samygina
Publikováno v:
Toxins, Vol 14, Iss 2, p 149 (2022)
Cobra cytotoxins (CTs) belong to the three-fingered protein family and possess membrane activity. Here, we studied cytotoxin 13 from Naja naja cobra venom (CT13Nn). For the first time, a spatial model of CT13Nn with both “water” and “membrane
Externí odkaz:
https://doaj.org/article/0070f421d8124d2aaff9386ae360706a
Publikováno v:
Toxins, Vol 14, Iss 2, p 88 (2022)
Cardiotoxins (CaTxs) are a group of snake toxins that affect the cardiovascular system (CVS). Two types (S and P) of CaTxs are known, but the exact differences in the effects of these types on CVS have not been thoroughly studied. We investigated cel
Externí odkaz:
https://doaj.org/article/b683c845f2344bb1a6bcad66c52a37df
Autor:
Olga N. Kuleshina, Elena V. Kruykova, Elena G. Cheremnykh, Leonid V. Kozlov, Tatyana V. Andreeva, Vladislav G. Starkov, Alexey V. Osipov, Rustam H. Ziganshin, Victor I. Tsetlin, Yuri N. Utkin
Publikováno v:
Toxins, Vol 12, Iss 5, p 325 (2020)
Snake venoms possess lethal activities against different organisms, ranging from bacteria to higher vertebrates. Several venoms were shown to be active against protozoa, however, data about the anti-protozoan activity of cobra and viper venoms are ve
Externí odkaz:
https://doaj.org/article/785fe931be6e4894b8ba5aa0a9443672
Autor:
Alexey V. Osipov, Tatiana I. Terpinskaya, Elena V. Kryukova, Vladimir S. Ulaschik, Lubov V. Paulovets, Elena A. Petrova, Ekaterina V. Blagun, Vladislav G. Starkov, Yuri N. Utkin
Publikováno v:
Toxins, Vol 6, Iss 3, Pp 784-795 (2014)
The effects of nerve growth factor (NGF) from cobra venom (cvNGF) on growth of Ehrlich ascites carcinoma (EAC) cells inoculated subcutaneously in mice have been studied. The carcinoma growth slows down, but does not stop, during a course of cvNGF inj
Externí odkaz:
https://doaj.org/article/4dc607348b68429bb5e3126c413d5ba9
Autor:
Alexey V. Osipov, Tatiana I. Terpinskaya, Tatiana E. Kuznetsova, Elena L. Ryzhkovskaya, Vladimir S. Lukashevich, Julia A. Rudnichenko, Vladimir S. Ulashchyk, Vladislav G. Starkov, Yuri N. Utkin
Publikováno v:
Toxins, Vol 9, Iss 9, p 274 (2017)
We showed recently that nerve growth factor (NGF) from cobra venom inhibited the growth of Ehrlich ascites carcinoma (EAC) inoculated subcutaneously in mice. Here, we studied the influence of anti-complementary cobra venom factor (CVF) and the non-st
Externí odkaz:
https://doaj.org/article/391b391273f34377b83800655e3c3ab0
Autor:
Sergey I. Kovalchuk, Rustam H. Ziganshin, Vladislav G. Starkov, Victor I. Tsetlin, Yuri N. Utkin
Publikováno v:
Toxins, Vol 8, Iss 4, p 105 (2016)
Venoms of most Russian viper species are poorly characterized. Here, by quantitative chromato-mass-spectrometry, we analyzed protein and peptide compositions of venoms from four Vipera species (V. kaznakovi, V. renardi, V. orlovi and V. nikolskii) in
Externí odkaz:
https://doaj.org/article/84d90fffc2ee44d2a52dc6e5a209c44c
Autor:
Alexey S. Averin, Alexey V. Berezhnov, Oleg Y. Pimenov, Miliausha H. Galimova, Vladislav G. Starkov, Victor I. Tsetlin, Yuri N. Utkin
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9259
Cardiotoxins (CaTx) of the three-finger toxin family are one of the main components of cobra venoms. Depending on the structure of the N-terminal or the central polypeptide loop, they are classified into either group I and II or P- and S-types, respe