Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vladislav G, Sharin"'
Autor:
Ahsan Farooqi, Christian Alvarez, David M. Irvin, Sharvari Dharmaiah, Jason T. Huse, Vladislav G. Sharin
Publikováno v:
Neuro Oncol
Gliomas are the most common primary malignant brain tumor in adults and mutational inactivation of histone chaperone ATRX is a critical molecular marker in the classification of high-grade glioma (HGG). ATRX loss occurs with concurrent mutations in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c898bd1e6797ccff77a1869d1343d143
https://europepmc.org/articles/PMC7650322/
https://europepmc.org/articles/PMC7650322/
Autor:
Vladislav G. Sharin, Ravesanker Ezhilarasan, Carla Danussi, Christian Alvarez, Jie Yang, Erik P. Sulman, Ahsan Farooqi, David M. Irvin, Sharvari Dharmaiah, Jason T. Huse
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-3 (2019)
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-3 (2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e01bafdee412800e84ca035a7243db7
https://pubmed.ncbi.nlm.nih.gov/31097032
https://pubmed.ncbi.nlm.nih.gov/31097032
Autor:
Luciano K. Jornada, Diogo Dominguini, Samira S. Valvassori, Jaqueline S. Generoso, Antônio Lúcio Teixeira, Vladislav G. Sharin, Lucas B. Souza, João Quevedo, Lutiana R. Simões, Tatiana Barichello
Publikováno v:
Neurochemical Research. 41:2771-2778
Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS) with a high mortality rate. In addition to causing severe neurological sequelae infectious diseases of the CNS can play a significant role in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04a7c5ce8f047543bea92b8dcad751f
https://doi.org/10.1007/s11064-016-1992-z
https://doi.org/10.1007/s11064-016-1992-z
Autor:
David M. Irvin, Christian Alvarez, Jason T. Huse, Ahsan Farooqi, Sharvari Dharmaiah, Hannah Roberts, Vladislav G. Sharin
Publikováno v:
Neuro Oncol
Current treatment for diffuse astrocytoma fails to address its underlying molecular mechanisms leading to inevitable disease progression and eventual patient death. Genomic studies have implicated ATRX alterations as critical to low grade glioma biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cc9a4e775f68c0ecdd49935c906072
https://doi.org/10.1093/neuonc/noaa215.121
https://doi.org/10.1093/neuonc/noaa215.121
BACKGROUND: Telomeres are terminal DNA elements found at chromosomal ends consisting of hexagonal repeats of (TTAGGG)(n,) which are essential for maintaining genomic stability. In glioblastoma, TERT promoter mutations occur in approximately 60–80%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8de013b85678e375a1ed2ba301dd67e
https://europepmc.org/articles/PMC6216518/
https://europepmc.org/articles/PMC6216518/
Autor:
Renan Antonio Ceretta, João Quevedo, Diogo Dominguini, Lutiana R. Simões, Tatiana Barichello, Antônio Lúcio Teixeira, Clarissa M. Comim, Jaqueline S. Generoso, Vladislav G. Sharin, Márcia Carvalho Vilela
Publikováno v:
Current Neurovascular Research. 12:253-261
Pneumococcal meningitis is characterized by high rates of mortality and long-term cognitive impairment. In this study, we evaluated the effects of interleukin (IL)-1 β receptor antagonist (IL-1Ra) on memory, cytokine, and brainderived neurotrophic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde2eea495ece4b22657953cde743d1b
https://doi.org/10.2174/1567202612666150605122200
https://doi.org/10.2174/1567202612666150605122200
Autor:
Christian Alvarez, J. Yang, S. Dharmiah, Erik P. Sulman, D. Irwin, Jason T. Huse, Ahsan Farooqi, Carla Danussi, Ravesanker Ezhilarasan, Vladislav G. Sharin
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 105:E98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca30f5057937f4c246d11f7f17591890
https://doi.org/10.1016/j.ijrobp.2019.06.2286
https://doi.org/10.1016/j.ijrobp.2019.06.2286
Autor:
Gretchen J. Darlington, Jingling Jin, Il Hwa Hong, Angela Mayor, Polina Iakova, Milton J. Finegold, Vladislav G. Sharin, Sayeepriyadarshini Anakk, Yanjun Jiang, David D. Moore, Nikolai A. Timchenko, Emily Sullivan
Publikováno v:
Hepatology. 57:1098-1106
One of the early events in the development of liver cancer is a neutralization of tumor suppressor proteins Rb, p53, hepatocyte nuclear factor 4α (HNF4α), and CCAAT/enhancer binding protein (C/EBP) α. The elimination of these proteins is mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980bc925b2ea46bff4e05071a58ea110
https://doi.org/10.1002/hep.26146
https://doi.org/10.1002/hep.26146
Autor:
Alexander Y. Kots, Ferid Murad, Emil Martin, Iraida Sharina, Kalpana Mujoo, Vladislav G. Sharin
Publikováno v:
Stem Cells and Development. 20:1287-1293
Nitric oxide (NO), an important mediator molecule in mammalian physiology, initiates a number of signaling mechanisms by activating the enzyme soluble guanylyl cyclase (sGC). Recently, a new role for NO/cyclic guanosine monophosphate signaling in emb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b995814e8d2f880c581bc597020b10
https://doi.org/10.1089/scd.2010.0411
https://doi.org/10.1089/scd.2010.0411
Autor:
Ferid Murad, Courtney Sloan, Alexander Y. Kots, Kalpana Mujoo, Byung-Kwon Choi, Emil Martin, Lubov E. Nikonoff, Vladislav G. Sharin
Publikováno v:
Nitric Oxide. 22:43-50
Our previous studies demonstrate a differential expression of nitric oxide (NO) signaling components in ES cells and our recent study demonstrated an enhanced differentiation of ES cells into myocardial cells with NO donors and soluble guanylyl cycla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3359a495310edd2dce396d6ce0cf05d2
https://doi.org/10.1016/j.niox.2009.11.007
https://doi.org/10.1016/j.niox.2009.11.007