Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vladislav Bugay"'
Autor:
Vladislav Bugay, Summer Rain Gregory, Matthieu Gibson Belanger-Coast, Raymond Zhao, Robert Brenner
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Organophosphates are used in agriculture as insecticides but are potentially toxic to humans when exposed at high concentrations. The mechanism of toxicity is through antagonism of acetylcholinesterase, which secondarily causes excess activation of c
Externí odkaz:
https://doaj.org/article/335e186f9ee1418db3ffb83b6cee6ca7
Autor:
Vladislav Bugay, Derek J. Wallace, Bin Wang, Irving Salinas, Adriana Paola Chapparo, Hudson Ryan Smith, Peter Herbert Dube, Edward G. Brooks, Kelly Ann Berg, Robert Brenner
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Dequalinium is used as an antimicrobial compound for oral health and other microbial infections. Derivatives of dequalinium, the bis-quinolinium cyclophanes UCL 1684 and UCL 1848, are high affinity SK potassium channel antagonists. Here we investigat
Externí odkaz:
https://doaj.org/article/1eb5d31a0367439e8883db9c5ddfbe54
Autor:
Fabio A. Vigil, Hindiael Belchior, Vladislav Bugay, Isabella I. Bazaldua, Aiola Stoja, Denise C. Dantas, Sang H. Chun, Austin Farmer, Eda Bozdemir, Deborah M. Holstein, Jose E. Cavazos, James D. Lechleiter, Robert Brenner, Mark S. Shapiro
Publikováno v:
Neurotherapeutics.
Autor:
Matthieu G. Belanger-Coast, Mei Zhang, Vladislav Bugay, Raul A. Gutierrez, Summer R. Gregory, Weifeng Yu, Robert Brenner
Publikováno v:
European journal of pharmacology. 925
Dequalinium chloride has been used primarily as antiseptic compounds, but recently has been investigated for its effects on specific targets, including muscarinic acetylcholine receptors. Here we investigated dequalinium chloride as an antagonist to
Publikováno v:
NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY.
Autor:
Shayne D. Hastings, Rafael J. Veraza, Deborah M. Holstein, Isamar Sanchez, Sang H Chun, Mark S. Shapiro, MaryAnn Hobbs, Robert Brenner, José E Cavazos, Shane Sprague, Chase M. Carver, Fabio A. Vigil, Eda Bozdemir, Vladislav Bugay, James D. Lechleiter
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 40:1256-1273
Nearly three million people in the USA suffer traumatic brain injury (TBI) yearly; however, there are no pre- or post-TBI treatment options available. KCNQ2-5 voltage-gated K+ channels underlie the neuronal “M current”, which plays a dominant rol
Autor:
Sarah M Khoury, Aiola Stoja, Liston Theodore E, Eda Bozdemir, Mark S. Shapiro, Liliana Espinoza, Shane Sprague, Fabio A. Vigil, Sang H Chun, Robert Brenner, Ceyda Tunca, Vladislav Bugay, James D. Lechleiter, Damian Lozano, Deborah M. Holstein, José E Cavazos
Publikováno v:
Neurotherapeutics
Traumatic brain injury (TBI) remains one of the greatest public health concerns with increasing morbidity and mortality rates worldwide. Our group reported that stimulation of astrocyte mitochondrial metabolism by P2Y(1) receptor agonists significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6782865a9d4318a1ec192e13befec7
https://doi.org/10.21203/rs.3.rs-145867/v1
https://doi.org/10.21203/rs.3.rs-145867/v1
Autor:
Alan Frazer, Vladislav Bugay, Robert Brenner, Flavia Regina Carreno, Alexandra Maxine McCoy, Daniel J. Lodge
Publikováno v:
Neuropsychopharmacology
Previous research has demonstrated that selective modulation of hippocampal transmission by systemic administration of an α5-GABA(A) receptor negative allosteric modulator, L-655,708, reproduces the sustained antidepressant-like (AD-like) effect of
Autor:
William Elliott, Vladislav Bugay, Eda Bozdemir, Deborah M. Holstein, Cassie Sprague, José E Cavazos, Sang H Chun, Fabio A. Vigil, James D. Lechleiter, David O. Zamora, Gregory Rule, Robert Brenner, Mark S. Shapiro
Publikováno v:
J Neurotrauma
Repetitive blast traumatic brain injury (TBI) affects numerous soldiers on the battlefield. Mild TBI has been shown to have long-lasting effects with repeated injury. We have investigated effects on neuronal excitability after repetitive, mild TBI in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb6ffdff6fcee89ce4236a3877a99e0
https://europepmc.org/articles/PMC7058993/
https://europepmc.org/articles/PMC7058993/
Autor:
Anthony T Chong, Hye Young Lee, Bumwhee Lee, Vladislav Bugay, Kunwoo Lee, Shree Panda, Niren Murthy, Robert Brenner, Hyo Min Park, Rodrigo Gonzales-Rojas
Publikováno v:
Nature biomedical engineering, vol 2, iss 7
Technologies that can safely edit genes in the brains of adult animals may revolutionize the treatment of neurological diseases and the understanding of brain function. Here, we demonstrate that intracranial injection of CRISPR–Gold, a nonviral del