Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Vladislav A Petyuk"'
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-26 (2022)
Abstract Background Theoretical analysis of signaling pathways can provide a substantial amount of insight into their function. One particular area of research considers signaling pathways capable of assuming two or more stable states given the same
Externí odkaz:
https://doaj.org/article/085b5d84695640dfad1e7c268c280579
Autor:
Aron S Buchman, Lei Yu, Vladislav A Petyuk, Chris Gaiteri, Shinya Tasaki, Katherine D Blizinsky, Julie A Schneider, Philip L De Jager, David A Bennett
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220968 (2019)
Alzheimer's disease and related disorders (ADRD) may manifest cognitive and non-cognitive phenotypes including motor impairment, suggesting a shared underlying biology. We tested the hypothesis that five cortical proteins identified from a gene netwo
Externí odkaz:
https://doaj.org/article/57c63d828bc54541bb22715df3e666a0
Autor:
Yehudit Hasin-Brumshtein, Arshad H Khan, Farhad Hormozdiari, Calvin Pan, Brian W Parks, Vladislav A Petyuk, Paul D Piehowski, Anneke Brümmer, Matteo Pellegrini, Xinshu Xiao, Eleazar Eskin, Richard D Smith, Aldons J Lusis, Desmond J Smith
Publikováno v:
eLife, Vol 5 (2016)
Previous studies had shown that the integration of genome wide expression profiles, in metabolic tissues, with genetic and phenotypic variance, provided valuable insight into the underlying molecular mechanisms. We used RNA-Seq to characterize hypoth
Externí odkaz:
https://doaj.org/article/0c8170174501445190a38cff232f6ee5
Autor:
Shahram Oveisgharan, Lei Yu, Katia de Paiva Lopes, Vladislav A. Petyuk, Shinya Tasaki, Ricardo Vialle, Vilas Menon, Yanling Wang, Philip L. De Jager, Julie A. Schneider, David A. Bennett
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Accumulation of amyloid-β (Aβ) and tau tangles are hallmarks of Alzheimer’s disease. Aβ is extracellular while tau tangles are typically intracellular, and it is unknown how these two proteinopathies are connected. Here, we use data of
Externí odkaz:
https://doaj.org/article/db373cb64bd548c290a7761d99ec2353
Autor:
Rebecca L. Winfree, Emma Nolan, Logan Dumitrescu, Kaj Blennow, Henrik Zetterberg, Katherine A. Gifford, Kimberly R. Pechman, Mabel Seto, Vladislav A. Petyuk, Yanling Wang, Julie Schneider, David A. Bennett, Angela L. Jefferson, Timothy J. Hohman, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Recent evidence suggests that Alzheimer’s disease (AD) genetic risk variants (rs1582763 and rs6591561) of the MS4A locus are genome-wide significant regulators of soluble TREM2 levels such that the minor allele of the protective variant (r
Externí odkaz:
https://doaj.org/article/7f931778e48b4a1db9dee9d86d867c84
Autor:
Praveen-Kumar Raj-Kumar, Xiaoying Lin, Tao Liu, Lori A. Sturtz, Marina A. Gritsenko, Vladislav A. Petyuk, Tyler J. Sagendorf, Brenda Deyarmin, Jianfang Liu, Anupama Praveen-Kumar, Guisong Wang, Jason E. McDermott, Anil K. Shukla, Ronald J. Moore, Matthew E. Monroe, Bobbie-Jo M. Webb-Robertson, Jeffrey A. Hooke, Leigh Fantacone-Campbell, Brad Mostoller, Leonid Kvecher, Jennifer Kane, Jennifer Melley, Stella Somiari, Patrick Soon-Shiong, Richard D. Smith, Richard J. Mural, Karin D. Rodland, Craig D. Shriver, Albert J. Kovatich, Hai Hu
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-24 (2024)
Abstract Background Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer death among women globally. Despite advances, there is considerable variation in clinical outcomes for patients with non-luminal A tumors, cl
Externí odkaz:
https://doaj.org/article/60e2f6b00711485594ffbd5654bfcc15
Autor:
Jessica L Martin, Phillip A Yates, Radika Soysa, Joshua F Alfaro, Feng Yang, Kristin E Burnum-Johnson, Vladislav A Petyuk, Karl K Weitz, David G Camp, Richard D Smith, Phillip A Wilmarth, Larry L David, Gowthaman Ramasamy, Peter J Myler, Nicola S Carter
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003938 (2014)
The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to env
Externí odkaz:
https://doaj.org/article/36e8f0994aaf4437ba1879260ecffd0a
Autor:
Anatole Ghazalpour, Brian Bennett, Vladislav A Petyuk, Luz Orozco, Raffi Hagopian, Imran N Mungrue, Charles R Farber, Janet Sinsheimer, Hyun M Kang, Nicholas Furlotte, Christopher C Park, Ping-Zi Wen, Heather Brewer, Karl Weitz, David G Camp, Calvin Pan, Roumyana Yordanova, Isaac Neuhaus, Charles Tilford, Nathan Siemers, Peter Gargalovic, Eleazar Eskin, Todd Kirchgessner, Desmond J Smith, Richard D Smith, Aldons J Lusis
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1001393 (2011)
The relationships between the levels of transcripts and the levels of the proteins they encode have not been examined comprehensively in mammals, although previous work in plants and yeast suggest a surprisingly modest correlation. We have examined t
Externí odkaz:
https://doaj.org/article/63664e45601942ab95c1f5cacfda19f8
Autor:
Steven E. Schutzer, Tao Liu, Chia-Feng Tsai, Vladislav A. Petyuk, Athena A. Schepmoes, Yi-Ting Wang, Karl K. Weitz, Jonas Bergquist, Richard D. Smith, Benjamin H. Natelson
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has given rise to the question whether they are distinct central nervous system
Externí odkaz:
https://doaj.org/article/90cc0b395f50449dbe56f0aabe733dc3
Autor:
Elena Hernández-Hernández, Fernando Yáñez-Gómez, Vladislav. A Petyuk, Philip. L De Jager, Sue Leurgans, Julie Schneider, David. A Bennet, William Honer, María Julia García-Fuster, Alfredo Ramos-Miguel
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S424-S425 (2023)
Externí odkaz:
https://doaj.org/article/66012cd5089446ffb309fba2fc241bb5