Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vladislav A Lushpa"'
Autor:
Vladislav A Lushpa, Marina V Goncharuk, Irina A Talyzina, Alexander S Arseniev, Eduard V Bocharov, Konstantin S Mineev, Sergey A Goncharuk
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304997 (2024)
Toll-like receptors (TLRs) are key players in the innate immune system. Despite the great efforts in TLR structural biology, today we know the spatial structures of only four human TLR intracellular TIR domains. All of them belong to one of five subf
Externí odkaz:
https://doaj.org/article/9761a2e62c224787ad9499a872968cd1
Autor:
Vladislav A. Lushpa, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra P. Luginina, Daniil D. Vakhrameev, Mikhail B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, Valentin I. Borshchevskiy, Xiaohui Wang, Konstantin S. Mineev
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Lushpa et al report the structure and dynamics of the TLR1 toll-interleukin like (TIR) cytoplasmic domain in both crystal and solution. They demonstrate that the TLR1 TIR domain is capable of specific binding of Zn with nanomolar affinity, which appe
Externí odkaz:
https://doaj.org/article/ba1903b9028f4b788d2c7b76bc761832
Autor:
Renata I. Zagitova, Konstantin V. Purtov, Aleksandr S. Shcheglov, Konstantin S. Mineev, Maxim A. Dubinnyi, Ivan N. Myasnyanko, Olga A. Belozerova, Vera G. Pakhomova, Valentin N. Petushkov, Natalia S. Rodionova, Vladislav A. Lushpa, Elena B. Guglya, Sergey Kovalchuk, Valeri B. Kozhemyako, Jeremy D. Mirza, Anderson G. Oliveira, Ilia V. Yampolsky, Zinaida M. Kaskova, Aleksandra S. Tsarkova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9466 (2023)
Biochemistry of bioluminescence of the marine parchment tubeworm Chaetopterus has been in research focus for over a century; however, the results obtained by various groups contradict each other. Here, we report the isolation and structural elucidati
Externí odkaz:
https://doaj.org/article/25b5183d42f94f708f38d592ae1c90b1
Autor:
Igor E. Kasheverov, Yulia A. Logashina, Fedor D. Kornilov, Vladislav A. Lushpa, Ekaterina E. Maleeva, Yuliya V. Korolkova, Jinpeng Yu, Xiaopeng Zhu, Dongting Zhangsun, Sulan Luo, Klara Stensvåg, Denis S. Kudryavtsev, Konstantin S. Mineev, Yaroslav A. Andreev
Publikováno v:
Toxins, Vol 15, Iss 1, p 28 (2022)
Nicotinic acetylcholine receptors (nAChRs) play an important role in the functioning of the central and peripheral nervous systems, and other organs of living creatures. There are several subtypes of nAChRs, and almost all of them are considered as p
Externí odkaz:
https://doaj.org/article/2e0a0500fc45433fb23a2f096657d870
Autor:
Vladislav A. Lushpa, Nadezhda S. Baleeva, Sergey A. Goncharuk, Marina V. Goncharuk, Alexander S. Arseniev, Mikhail S. Baranov, Konstantin S. Mineev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11361 (2022)
NanoFAST is a fluorogen-activating protein and can be considered one of the smallest encodable fluorescent tags. Being a shortened variant of another fluorescent tag, FAST, nanoFAST works nicely only with one out of all known FAST ligands. This subst
Externí odkaz:
https://doaj.org/article/691a15dd2b434d068d69e39d47690e1b
Autor:
Albert F. Arutyunyan, Alexey A. Kostyukov, Vladislav A. Lushpa, Konstantin S. Mineev, Sergey P. Korolev, Marina B. Gottikh, Regina R. Klimova, Alla A. Kushch, Kseniya V. Kalabina, Olga Yu. Susova, Alexei L. Zhuze
Publikováno v:
Medicinal Chemistry Research. 32:587-599
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cb0738323ece8021db25222fe916717
https://doi.org/10.1007/s00044-023-03017-x
https://doi.org/10.1007/s00044-023-03017-x
Autor:
Albert F. Arutyunyan, Alexey Kostyukov, Vladislav A. Lushpa, Konstantin S. Mineev, Sergey P. Korolev, Marina B. Gottikh, Regina R. Klimova, Alla A. Kushch, Kseniya V. Kalabina, Olga Yu. Susova, Alexei L. Zhuze
A new series of AT-specific minor groove DNA ligands (DB3P(n); n = 1,2,3,4) were synthesized and their spectral, biological and virological properties were investigated in water media. The variable length of methylene spacer in middle of molecule str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2a6eaa9e10c9e360480e03959fcb78
https://doi.org/10.21203/rs.3.rs-2281778/v1
https://doi.org/10.21203/rs.3.rs-2281778/v1
Autor:
Daniil Vakhrameev, Xiaohui Wang, Irina A. Talyzina, Arthur O. Zalevsky, Sergey A. Goncharuk, Mikhail B. Shevtsov, Konstantin S. Mineev, Valentin Borshchevskiy, Vladislav A. Lushpa, Alexander S. Arseniev, Marina V. Goncharuk, Aleksandra Luginina, Cong Lin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications biology 4(1), 1003 (2021). doi:10.1038/s42003-021-02532-0
Communications Biology
'Communications Biology ', vol: 4, pages: 1003-1-1003-12 (2021)
Communications biology 4(1), 1003 (2021). doi:10.1038/s42003-021-02532-0
Communications Biology
'Communications Biology ', vol: 4, pages: 1003-1-1003-12 (2021)
Toll-like receptors (TLRs) play an important role in the innate immune response. While a lot is known about the structures of their extracellular parts, many questions are still left unanswered, when the structural basis of TLR activation is analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bddd7624c623c99bd007c466f21ba1
https://doaj.org/article/ba1903b9028f4b788d2c7b76bc761832
https://doaj.org/article/ba1903b9028f4b788d2c7b76bc761832
Autor:
Viktoria A. Ikonnikova, Nadezhda S. Baleeva, Pavel N. Solyev, Vladislav A. Lushpa, Andrey A. Mikhaylov, Alexander A. Korlyukov, Mikhail S. Baranov, Alexander D. Volodin, Vasilissa V. Shirokova
Publikováno v:
Synthesis. 53:4689-4699
Directly accessible 8-substituted tetrahydroquinolines undergo 1,5-hydride-shift-triggered cyclization to provide difficult to access julolidine derivatives in yields of 21–98% under scandium(III) triflate catalysis. Additionally, the scope of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b585c53eddb531d5c05b968b8bc383
https://doi.org/10.1055/a-1559-2728
https://doi.org/10.1055/a-1559-2728
Autor:
Vladislav А. Lushpa, Andrei V. Kuleshov, Mikhail S. Baranov, Aleksander А. Korlyukov, Pavel N. Solyev, Andrey А. Mikhaylov, Vadim S. Kublitskii
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1092-1096
Nucleophilic cyclopropanation of arylideneimidazolones possessing a peripheral chiral center and the subsequent fractional crystallization of diastereomers allows access to the compounds with an enantiomerically uniform configuration of the spirocycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8475633309d11ca78f5998842ca7fbdb
https://doi.org/10.1007/s10593-020-02778-2
https://doi.org/10.1007/s10593-020-02778-2