Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Vladislav, Belyy"'
Publikováno v:
eLife, Vol 11 (2022)
Protein folding homeostasis in the endoplasmic reticulum (ER) is regulated by a signaling network, termed the unfolded protein response (UPR). Inositol-requiring enzyme 1 (IRE1) is an ER membrane-resident kinase/RNase that mediates signal transmissio
Externí odkaz:
https://doaj.org/article/8e12a13545394daca001d70d0014eef1
Publikováno v:
eLife, Vol 11 (2022)
The mitochondrial AAA (ATPase Associated with diverse cellular Activities) protein ATAD1 (in humans; Msp1 in yeast) removes mislocalized membrane proteins, as well as stuck import substrates from the mitochondrial outer membrane, facilitating their r
Externí odkaz:
https://doaj.org/article/d033a7156b8f424996f2a09a5d5cc31b
Autor:
Vladislav Belyy, Sheng-Min Shih, Jigar Bandaria, Yongjian Huang, Rosalie E. Lawrence, Roberto Zoncu, Ahmet Yildiz
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Tracking single molecules in living cells is difficult or impractical owing to their high density. Here the authors introduce a technique of repeatedly photobleaching fluorophores at the boundary of a region of interest, thereby controlling the numbe
Externí odkaz:
https://doaj.org/article/77efbc9571114b969331b9cd398322cf
Publikováno v:
eLife. 11
The mitochondrial AAA (ATPase Associated with diverse cellular Activities) protein ATAD1 (in humans; Msp1 in yeast) removes mislocalized membrane proteins, as well as stuck import substrates from the mitochondrial outer membrane, facilitating their r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcf19970070c38cfafab48f64c410ba
https://doi.org/10.7554/elife.73941
https://doi.org/10.7554/elife.73941
Publikováno v:
Nature physics
The cytoskeleton forms a dynamic network that generates fluctuations larger than thermal agitation of the cytoplasm1. Here, we tested whether dynein, a minus-end-directed microtubule (MT) motor2, can harness energy from these fluctuations using optic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddfd61761b9df657248e772844d6d7a9
http://europepmc.org/articles/PMC8049612
http://europepmc.org/articles/PMC8049612
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 3
The endoplasmic reticulum (ER) membrane-resident stress sensor inositol-requiring enzyme 1 (IRE1) governs the most evolutionarily conserved branch of the unfolded protein response. Upon sensing an accumulation of unfolded proteins in the ER lumen, IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4279722cd34689d0758b8074c17d1a58
https://doi.org/10.1073/pnas.1915311117
https://doi.org/10.1073/pnas.1915311117
Publikováno v:
eLife. 11
Protein folding homeostasis in the endoplasmic reticulum (ER) is regulated by a signaling network, termed the unfolded protein response (UPR). Inositol-requiring enzyme 1 (IRE1) is an ER membrane-resident kinase/RNase that mediates signal transmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bfe07aad344555c227e4708d7dffbb
https://pubmed.ncbi.nlm.nih.gov/35730415
https://pubmed.ncbi.nlm.nih.gov/35730415
Autor:
Un Seng Chio, Ming Sun, Adolfo García-Sastre, R.A. Saunders, Niv Dobzinski, Jiahao Liang, Vladislav Belyy, Peter Walter, Caleigh M. Azumaya, Beth S. Zha, Fei Li, Morgane Boone, Kris M. White, Yuwei Liu, Kaitlin Schaefer, Frank R. Moss, Aashish Manglik, Nevan J. Krogan, Michael C. Thompson, Nick Hoppe, Alexandrea N. Rizo, Axel F. Brilot, Danielle L. Swaney, S. Dickinson, Corie Y. Ralston, Bryan Faust, Devan Diwanji, A.W. Barile-Hill, Camille R. Simoneau, Smriti Sangwan, Sayan Gupta, Benjamin Barsi-Rhyne, Mingliang Jin, Veronica V. Rezelj, Huong T. Kratochvil, Silke Nock, David Bulkley, Kristoffer E. Leon, Marco Vignuzzi, Sergei Pourmal, Henry C. Nguyen, Thomas H. Pospiech, Gregory E. Merz, Raphael Trenker, Cynthia M. Chio, Yanxin Liu, Kaihua Zhang, Meghna Gupta, Aditya A. Anand, Cristina Puchades, M. Zimanyi, Amber M. Smith, Michael Schoof, Christian B. Billesbølle, Melanie Ott, Ishan Deshpande
Publikováno v:
Science (New York, N.y.)
Science
Science
Nanobodies that neutralize Monoclonal antibodies that bind to the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show therapeutic promise but must be produced in mammalian cells and need to be delivered intravenously. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c74ff65944a0933cee2079cf142211
https://pubmed.ncbi.nlm.nih.gov/32817938
https://pubmed.ncbi.nlm.nih.gov/32817938
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, vol 31, iss 7
Molecular biology of the cell, vol 31, iss 7
Mitochondrial function depends crucially on the maintenance of multiple mitochondrial DNA (mtDNA) copies. Surprisingly, the cellular mechanisms regulating mtDNA copy number remain poorly understood. Through a systematic high-throughput approach in Sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9acff954bdc3fa35d6a52d41528791