Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Vladimir Zarnitsyn"'
Autor:
Rhonda C Kines, Vladimir Zarnitsyn, Teresa R Johnson, Yuk-Ying S Pang, Kizzmekia S Corbett, John D Nicewonger, Anu Gangopadhyay, Man Chen, Jie Liu, Mark R Prausnitz, John T Schiller, Barney S Graham
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120797 (2015)
Human papilloma virus-like particles (HPV VLP) serve as the basis of the current licensed vaccines for HPV. We have previously shown that encapsidation of DNA expressing the model antigen M/M2 from respiratory syncytial virus (RSV) in HPV pseudovirio
Externí odkaz:
https://doaj.org/article/5ba8cc99ac9c4bd48b135b83eba41899
Autor:
Jeffrey J Landers, Katarzyna W Janczak, Akhilesh Kumar Shakya, Vladimir Zarnitsyn, Samirkumar R Patel, James R Baker, Harvinder Singh Gill, Jessica J O'Konek
Publikováno v:
Immunotherapy
Aim: Epicutaneous immunotherapy (EPIT) with peanut has been demonstrated to be safe but efficacy may be limited by allergen uptake through the skin barrier. To enhance allergen uptake into the skin, the authors used peanut-coated microneedles and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d5a42fac84b3ab7dc22be7fc8a9310
https://europepmc.org/articles/PMC9043875/
https://europepmc.org/articles/PMC9043875/
Autor:
Brian C. Gilger, Liujiang Song, Samirkumar Patel, Megan Cullen, Telmo Llanga, Elizabeth Crabtree, Jacklyn H. Salmon, Vladimir Zarnitsyn, Allison Blanchard, Matthew L. Hirsch
Publikováno v:
Cornea
Supplemental Digital Content is Available in the Text.
Purpose: Drug delivery directly to the corneal stroma currently relies on microscopic injections that demonstrate low reproducibility and clinician-dependent variability. With use of biologi
Purpose: Drug delivery directly to the corneal stroma currently relies on microscopic injections that demonstrate low reproducibility and clinician-dependent variability. With use of biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5037f4bdcb9c29b98c073160f6ef60
https://doi.org/10.1097/ico.0000000000002182
https://doi.org/10.1097/ico.0000000000002182
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:AB237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7018efcd049e741d53b2ec9b00d4a470
https://doi.org/10.1016/j.jaci.2020.12.013
https://doi.org/10.1016/j.jaci.2020.12.013
Autor:
Verena Saller, Alexander Vincent Anstey, Chris Gateley, Marc Pearton, Sion Coulman, James Caradoc Birchall, Vladimir Zarnitsyn
Publikováno v:
Journal of Controlled Release. 160:561-569
Microneedle delivery of nucleic acids, in particular plasmid DNA (pDNA), to the skin represents a potential new approach for the clinical management of genetic skin diseases and cutaneous cancers, and for intracutaneous genetic immunization. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed583c93209c0a443f9011c6ee73a887
https://doi.org/10.1016/j.jconrel.2012.04.005
https://doi.org/10.1016/j.jconrel.2012.04.005
Autor:
Dimitrios G. Koutsonanos, Vladimir Zarnitsyn, Bao-Zhong Wang, Ioanna Skountzou, Mark R. Prausnitz, Maria del Pilar Martin, William C. Weldon, Richard W. Compans
Publikováno v:
Clinical and Vaccine Immunology. 18:647-654
The emergence of the swine-origin 2009 influenza pandemic illustrates the need for improved vaccine production and delivery strategies. Skin-based immunization represents an attractive alternative to traditional hypodermic needle vaccination routes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11760bc2f206b2f1869f7f5269dc76a
https://doi.org/10.1128/cvi.00435-10
https://doi.org/10.1128/cvi.00435-10
Autor:
Richard W. Compans, Maria del Pilar Martin, Seong-O Choi, Sean P. Sullivan, Jeong Woo Lee, Niren Murthy, Mark R. Prausnitz, Vladimir Zarnitsyn, Ioanna Skountzou, Dimitrios G. Koutsonanos
Publikováno v:
Nature Medicine. 16:915-920
Influenza prophylaxis would benefit from a vaccination method enabling simplified logistics and improved immunogenicity without the dangers posed by hypodermic needles. Here we introduce dissolving microneedle patches for influenza vaccination using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50ad2fea62d96ddc29e08e2c591754f
https://doi.org/10.1038/nm.2182
https://doi.org/10.1038/nm.2182
Autor:
Chinglai Yang, Ling Ye, Ioanna Skountzou, Mark R. Prausnitz, Harvinder S. Gill, Qiyun Zhu, Lei Pan, Zhiyuan Wen, Vladimir Zarnitsyn, Yulong Gao, Richard W. Compans
Publikováno v:
Proceedings of the National Academy of Sciences. 106:7968-7973
Influenza prophylaxis would benefit from a simple method to administer influenza vaccine into skin without the need for hypodermic needles. In this study, solid metal microneedle arrays (MNs) were investigated as a system for cutaneous vaccine delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e509d69d1b4d9ea0930265288d708c
https://doi.org/10.1073/pnas.0812652106
https://doi.org/10.1073/pnas.0812652106
Publikováno v:
Biophysical Journal. 95:4124-4138
Cells exposed to acoustic cavitation and other mechanical stresses can be transiently permeabilized to permit intracellular uptake of molecules, including drugs, proteins, and genes. Microscopic imaging and other studies suggest that intracellular lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefb4c33d92364c0af520ac2725af850
https://doi.org/10.1529/biophysj.108.131664
https://doi.org/10.1529/biophysj.108.131664
Publikováno v:
Technology in Cancer Research & Treatment. 6:433-442
Treatment of brain cancer is limited in part by inefficient intracellular delivery of drugs and DNA for chemotherapy and gene therapy, respectively. This study tested the hypothesis that ultrasound may be used to enhance intracellular delivery and ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84b67926009efa1bb3e63d3c6c7ccbc
https://doi.org/10.1177/153303460700600509
https://doi.org/10.1177/153303460700600509