Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Vladimir Y. Lugovtsev"'
Autor:
Nicolette Lee, Alexey M Khalenkov, Vladimir Y Lugovtsev, Derek D Ireland, Anastasia P Samsonova, Nicolai V Bovin, Raymond P Donnelly, Natalia A Ilyushina
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195525 (2018)
We applied an in vitro selection approach using two different plant lectins that bind to α2,3- or α2,6-linked sialic acids to determine which genetic changes of the A/California/04/09 (H1N1) virus alter hemagglutinin (HA) receptor binding toward α
Externí odkaz:
https://doaj.org/article/d44b457772154343ac831c6b616d3835
Autor:
Natalia A Ilyushina, Vladimir Y Lugovtsev, Anastasia P Samsonova, Faruk G Sheikh, Nicolai V Bovin, Raymond P Donnelly
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181999 (2017)
Influenza A viruses pose a constant potential threat to human health. In view of the innate antiviral activity of interferons (IFNs) and their potential use as anti-influenza agents, it is important to know whether viral resistance to these antiviral
Externí odkaz:
https://doaj.org/article/2c516d0fe02f4b2598146900a8b03271
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75014 (2013)
Single-cell clones have been established from the MDCK cell line, characterized for their morphology and evaluated for their suitability for influenza virus research. Three discrete cell morphotypes were identified using light microscopy. Besides mor
Externí odkaz:
https://doaj.org/article/6857641d4a48410fa96500e12b0a6325
Autor:
Vladimir Y. Lugovtsev, Nicolai V. Bovin, Anastasia Kan, Natalia A. Ilyushina, Simone E. Adams, Raymond P. Donnelly
Publikováno v:
Antimicrob Agents Chemother
Each year, 5% to 20% of the population of the United States becomes infected with influenza A virus. Combination therapy with two or more antiviral agents has been considered a potential treatment option for influenza virus infection. However, the cl
Autor:
Natalia A. Ilyushina, Nicolette Lee, Anastasia Kan, Nicolai V. Bovin, Vladimir Y. Lugovtsev, Raymond P. Donnelly
Publikováno v:
Virology. 549
Influenza B viruses cause seasonal epidemics and are a considerable burden to public health. To understand their adaptation capability, we examined the genetic changes that occurred following 15 serial passages of two influenza B viruses, B/Brisbane/
Autor:
Nicolette Lee, Simone E. Adams, Vladimir Y. Lugovtsev, Raymond P. Donnelly, Natalia A. Ilyushina, Anastasia Kan
Publikováno v:
Antiviral research. 169
Neuraminidase inhibitors (NAIs) play a key role in the management of influenza. Given the limited number of FDA-approved anti-influenza drugs, evaluation of potential drug-resistant variants is of high priority. Two NA mutations, V116A and I117V, are
Autor:
Nicolette Lee, Natalia A. Ilyushina, Raymond P. Donnelly, Derek D. C. Ireland, Nicolai V. Bovin, Vladimir Y. Lugovtsev, Anastasia P. Samsonova, Alexey Khalenkov
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0195525 (2018)
PLoS ONE, Vol 13, Iss 4, p e0195525 (2018)
We applied an in vitro selection approach using two different plant lectins that bind to α2,3- or α2,6-linked sialic acids to determine which genetic changes of the A/California/04/09 (H1N1) virus alter hemagglutinin (HA) receptor binding toward α
Autor:
Anastasia P. Samsonova, Natalia A. Ilyushina, Vladimir Y. Lugovtsev, Faruk Sheikh, Raymond P. Donnelly, Nicolai V. Bovin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181999 (2017)
PLoS ONE, Vol 12, Iss 7, p e0181999 (2017)
Influenza A viruses pose a constant potential threat to human health. In view of the innate antiviral activity of interferons (IFNs) and their potential use as anti-influenza agents, it is important to know whether viral resistance to these antiviral
Autor:
Hongquan Wan, Raymond P. Donnelly, Maryna C. Eichelberger, Laura Couzens, Vladimir Y. Lugovtsev, Xiaoquan Wang, Nicolai V. Bovin, Jin Gao, Natalia A. Ilyushina
Publikováno v:
Journal of virology. 91(2)
Influenza A H3N2 variant [A(H3N2)v] viruses, which have caused human infections in the United States in recent years, originated from human seasonal H3N2 viruses that were introduced into North American swine in the mid-1990s, but they are antigenica
Autor:
Wei Wang, Ollie Williams, Hang Xie, Falko Schmeisser, Joseph Besho, Zhiping Ye, Jackeline Soto, Carol D. Weiss, Rachel Friedman, Jerry P. Weir, Vladimir Y. Lugovtsev
Publikováno v:
Influenza and Other Respiratory Viruses. 7:480-490
Aims and Methods To facilitate antigenic characterization of the influenza A 2009 pandemic H1N1 [A(H1N1)pdm09] hemagglutinin (HA), we generated a panel of murine monoclonal antibodies (mAbs) using as the immunogen mammalian-derived virus-like particl