Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Vladimir Vigont"'
Autor:
Vladimir Vigont, Evgeny Nekrasov, Alexey Shalygin, Konstantin Gusev, Sergey Klushnikov, Sergey Illarioshkin, Maria Lagarkova, Sergey L. Kiselev, Elena Kaznacheyeva
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Neurodegenerative pathologies are among the most serious and socially significant problems of modern medicine, along with cardiovascular and oncological diseases. Several attempts have been made to prevent neuronal death using novel drugs targeted to
Externí odkaz:
https://doaj.org/article/37561a70256a4dc488738b4fe63e6e30
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 624, p 624 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The development of cell reprogramming technologies became a breakthrough in the creation of new models of human diseases, including neurodegenerative pathologies. The iPSCs-based models allow for the studying of both hereditary and sporadic cases of
Publikováno v:
Biophysical Journal. 121:373a
Publikováno v:
Acta Naturae. 9:34-46
Huntingtons disease (HD) is a severe inherited neurodegenerative disorder characterized by motor dysfunction, cognitive decline, and mental impairment. At the molecular level, HD is caused by a mutation in the first exon of the gene encoding the hunt
Publikováno v:
Biophysical Journal. 120:52a
Publikováno v:
Biophysical Journal. 118:404a
Autor:
Yu A Seliverstov, Sergey N. Illarioshkin, S. A. Klyushnikov, Elena Kaznacheyeva, Vladimir Vigont
Publikováno v:
Biochemistry. Biokhimiia. 83(9)
Huntington's disease (HD) is a severe autosomal dominant neurodegenerative disorder characterized by a combination of motor, cognitive, and psychiatric symptoms, atrophy of the basal ganglia and the cerebral cortex, and inevitably progressive course
Autor:
Katsuhiko Mikoshiba, Elena Kaznacheyeva, Vladimir Vigont, Jacek Kuznicki, Vasilisa A. Boeva, Magdalena Czeredys
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Huntington’s disease (HD) is a hereditary neurodegenerative disease that is caused by polyglutamine expansion within the huntingtin (HTT) gene. One of the cellular activities that is dysregulated in HD is store-operated calcium entry (SOCE), a proc
Autor:
Ksenia Skobeleva, Konstantin Gusev, Alexey Shalygin, E V Kaznacheeva, L. N. Glushankova, Dmitrii Kolesnikov, M. A. Ryazantseva, Vladimir Vigont, A. Yu. Skopin
Publikováno v:
Bulletin of experimental biology and medicine. 165(2)
Store-operated channels activated in response to intracellular calcium store depletion represent the main pathway of calcium entry from the extracellular space in nonelectroexcitable cells. Adapter proteins organize the components of this system into
Publikováno v:
Biophysical Journal. 114:285a-286a