Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety

Autor: Vladimir Burmistrov, Christophe Morisseau, Denis A. Babkov, Tatiana Golubeva, Dmitry Pitushkin, Elena V. Sokolova, Vladimir Vasipov, Yaroslav Kuznetsov, Sergey V. Bazhenov, Uliana S. Novoyatlova, Nikolay A. Bondarev, Ilya V. Manukhov, Victoria Osipova, Nadezhda Berberova, Alexander A. Spasov, Gennady M. Butov, Bruce D. Hammock

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10710
International journal of molecular sciences, vol 23, iss 18

The inhibitory potency of the series of inhibitors of the soluble epoxide hydrolase (sEH) based on the selenourea moiety and containing adamantane and aromatic lipophilic groups ranges from 34.3 nM to 1.2 μM. The most active compound 5d possesses al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951fdc67905743bd17c78ce7da903ad3
https://doi.org/10.3390/ijms231810710