Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vladimir V. Ternovoi"'
Publikováno v:
Laboratory Investigation. 86:748-766
The clinical outcome for osteosarcoma (OS) remains discouraging despite efforts to optimize treatment using conventional modalities including surgery, radiotherapy and chemotherapy. Novel therapeutic approaches based on our expanding understanding of
Autor:
Vladimir V. Ternovoi, André Lieber, Dmitry M. Shayakhmetov, Zong Yi Li, Helen Gharwan, Anuj Gaggar
Publikováno v:
Journal of Virology. 77:3712-3723
Most of the presently used adenovirus (Ad) vectors are based on serotype 5. However, the application of these vectors is limited by the native tropism of Ad5. To address this problem, a series of fiber chimeric vectors were produced to take advantage
Autor:
Nancy J. Cox, Vladimir V. Ternovoi, Gene P. Siegal, Bruce F. Smith, Henry J. Baker, David T. Curiel, Anton V. Borovjagin
Publikováno v:
Cancer biotherapyradiopharmaceuticals. 21(6)
Conditionally replicative adenoviruses (CRAds) are engineered to replicate only in the target tissue and destroy tumor through their cytopathic effect. Because of restricted in vivo replication, it is difficult to model behavior of human Ad5-based ve
Publikováno v:
The Journal of general virology. 86(Pt 12)
Canine adenovirus type 2 (CAV2) has become an attractive vector for gene therapy because of its non-pathogenicity and the lack of pre-existing neutralizing antibodies against this virus in the human population. Additionally, this vector has been prop
Autor:
Long P. Le, Hongju Wu, Angel A. Rivera, Vladimir V. Ternovoi, Gene P. Siegal, M. Wang, David T. Curiel, Bruce F. Smith, Joel N. Glasgow
Publikováno v:
Gene therapy. 13(5)
The full realization of conditionally replicative adenoviruses (CRAds) for cancer therapy has been hampered by the limited knowledge of CRAd function in vivo and particularly in an immunocompetent host. To address this issue, we previously proposed a
Autor:
Natalya Belousova, Vladimir V. Ternovoi, David T. Curiel, Bruce F. Smith, Long P. Le, Gene P. Siegal
Publikováno v:
Journal of virology. 79(2)
Development of immunocompetent patient-like models that allow direct analysis of human adenovirus-based conditionally replicative adenoviruses (CRAds) would be beneficial for the advancement of these oncolytic agents. To this end, we explored the pos
Autor:
Bruce F. Smith, David T. Curiel, Vladimir V. Ternovoi, Anton V. Borovjagin, Henry J. Baker, Nancy Cox, Gene P. Siegal
Publikováno v:
Cancer Biotherapy & Radiopharmaceuticals; Dec2006, Vol. 21 Issue 6, p601-606, 6p