Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Vladimir V. Poroikov"'
Autor:
Anastasia V. Rudik, Alexander V. Dmitriev, Alexey A. Lagunin, Dmitry A. Filimonov, Vladimir V. Poroikov
Publikováno v:
ACS Omega, Vol 8, Iss 48, Pp 45774-45778 (2023)
Externí odkaz:
https://doaj.org/article/20f971efae70422da3963e87536132a7
Autor:
Ekaterina A. Stolbova, Leonid A. Stolbov, Dmitry A. Filimonov, Vladimir V. Poroikov, Olga A. Tarasova
Publikováno v:
Viruses, Vol 16, Iss 7, p 1132 (2024)
Drug resistance of pathogens, including viruses, is one of the reasons for decreased efficacy of therapy. Considering the impact of HIV type 1 (HIV-1) on the development of progressive immune dysfunction and the rapid development of drug resistance,
Externí odkaz:
https://doaj.org/article/f5000b0cdb064fc68023a42b263e65b7
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThere are difficulties in creating direct antiviral drugs for all viruses, including new, suddenly arising infections, such as COVID-19. Therefore, pathogenesis-directed therapy is often necessary to treat severe viral infections and como
Externí odkaz:
https://doaj.org/article/93d1bca0a802455a9f7856e491bbdcc1
Autor:
Anastasiia Iu. Paremskaia, Anastassia V. Rudik, Dmitry A. Filimonov, Alexey A. Lagunin, Vladimir V. Poroikov, Olga A. Tarasova
Publikováno v:
Viruses, Vol 15, Iss 11, p 2245 (2023)
Predicting viral drug resistance is a significant medical concern. The importance of this problem stimulates the continuous development of experimental and new computational approaches. The use of computational approaches allows researchers to increa
Externí odkaz:
https://doaj.org/article/9b1ff66c141b42b7bbbf74f3888e5d9a
Publikováno v:
Marine Drugs, Vol 19, Iss 6, p 324 (2021)
This review focuses on the rare group of carbon-bridged steroids (CBS) and triterpenoids found in various natural sources such as green, yellow-green, and red algae, marine sponges, soft corals, ascidians, starfish, and other marine invertebrates. In
Externí odkaz:
https://doaj.org/article/317fd7d79066447ea8f92cbd79062a4a
Autor:
Alexander V. Dmitriev, Anastassia V. Rudik, Dmitry A. Karasev, Pavel V. Pogodin, Alexey A. Lagunin, Dmitry A. Filimonov, Vladimir V. Poroikov
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 538 (2021)
Drug–drug interactions (DDIs) can cause drug toxicities, reduced pharmacological effects, and adverse drug reactions. Studies aiming to determine the possible DDIs for an investigational drug are part of the drug discovery and development process a
Externí odkaz:
https://doaj.org/article/859be6f3d7664ecf89e76b3f8d5e9002
Autor:
Valery M. Dembitsky, Ekaterina Ermolenko, Nick Savidov, Tatyana A. Gloriozova, Vladimir V. Poroikov
Publikováno v:
Molecules, Vol 26, Iss 3, p 686 (2021)
Polycyclic endoperoxides are rare natural metabolites found and isolated in plants, fungi, and marine invertebrates. The purpose of this review is a comparative analysis of the pharmacological potential of these natural products. According to PASS (P
Externí odkaz:
https://doaj.org/article/c83c356bc258493d83c840547fb8bb43
Autor:
Ekaterina V. Ermolenko, Andrey B. Imbs, Tatyana A. Gloriozova, Vladimir V. Poroikov, Tatyana V. Sikorskaya, Valery M. Dembitsky
Publikováno v:
Marine Drugs, Vol 18, Iss 12, p 613 (2020)
The review is devoted to the chemical diversity of steroids produced by soft corals and their determined and potential activities. There are about 200 steroids that belong to different types of steroids such as secosteroids, spirosteroids, epoxy- and
Externí odkaz:
https://doaj.org/article/fa3b17473a7e4d5c90b2ee4b99ef6b56
Autor:
Alexey A. Lagunin, Maria A. Romanova, Anton D. Zadorozhny, Natalia S. Kurilenko, Boris V. Shilov, Pavel V. Pogodin, Sergey M. Ivanov, Dmitry A. Filimonov, Vladimir V. Poroikov
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Estimation of interaction of drug-like compounds with antitargets is important for the assessment of possible toxic effects during drug development. Publicly available online databases provide data on the experimental results of chemical interactions
Externí odkaz:
https://doaj.org/article/eadd412cfcc94ac4b99fb31fcd26d8e2
Autor:
Leonid A. Stolbov, Dmitry S. Druzhilovskiy, Dmitry A. Filimonov, Marc C. Nicklaus, Vladimir V. Poroikov
Publikováno v:
Molecules, Vol 25, Iss 1, p 87 (2019)
Despite the achievements of antiretroviral therapy, discovery of new anti-HIV medicines remains an essential task because the existing drugs do not provide a complete cure for the infected patients, exhibit severe adverse effects, and lead to the app
Externí odkaz:
https://doaj.org/article/921c073ac82a4b7fb4753a50ea096bd8