Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Vladimir V Shuvaev"'
Autor:
Raisa Kiseleva, Colin F Greineder, Carlos H Villa, Elizabeth D Hood, Vladimir V Shuvaev, Jing Sun, Ann-Marie Chacko, Valsamma Abraham, Horace M DeLisser, Vladimir R Muzykantov
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169537 (2017)
Monoclonal antibodies (mAbs) directed to extracellular epitopes of human and mouse Platelet Endothelial Cell Adhesion Molecule-1 (CD31 or PECAM-1) stimulate binding of other mAbs to distinct adjacent PECAM-1 epitopes. This effect, dubbed Collaborativ
Externí odkaz:
https://doaj.org/article/9155c748285141548f446cfe89f90dc4
Autor:
M Carme Coll Ferrer, Vladimir V Shuvaev, Blaine J Zern, Russell J Composto, Vladimir R Muzykantov, David M Eckmann
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102329 (2014)
Lysozyme dextran nanogels (NG) have great potential in vitro as a drug delivery platform, combining simple chemistry with rapid uptake and cargo release in target cells with "stealth" properties and low toxicity. In this work, we study for the first
Externí odkaz:
https://doaj.org/article/5e39f1d9f7e24a8bb220d96a423d3607
Autor:
Hamideh Parhiz, Vladimir V. Shuvaev, Qin Li, Tyler E. Papp, Awurama A. Akyianu, Ruiqi Shi, Amir Yadegari, Hamna Shahnawaz, Sean C. Semple, Barbara L. Mui, Drew Weissman, Vladimir R. Muzykantov, Patrick M. Glassman
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102175- (2024)
RNA therapeutics are an emerging, powerful class of drugs with potential applications in a wide range of disorders. A central challenge in their development is the lack of clear pharmacokinetic (PK)-pharmacodynamic relationship, in part due to the si
Externí odkaz:
https://doaj.org/article/7f789f117b494a00a874576d1146347e
Autor:
Vladimir V Shuvaev, Jingyan Han, Samira Tliba, Evguenia Arguiri, Melpo Christofidou-Solomidou, Servio H Ramirez, Holly Dykstra, Yuri Persidsky, Dmitriy N Atochin, Paul L Huang, Vladimir R Muzykantov
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77002 (2013)
Pro-inflammatory activation of vascular endothelium is implicated in pathogenesis of severe conditions including stroke, infarction and sepsis. We have recently reported that superoxide dismutase (SOD) conjugated with antibodies (Ab/SOD) that provide
Externí odkaz:
https://doaj.org/article/394d1782bbd244f4af6bb830beeb475e
Autor:
Brian M. Leonard, Vladimir V. Shuvaev, Trent A. Bullock, Kalpani N. Udeni Galpayage Dona, Vladimir R. Muzykantov, Allison M. Andrews, Servio H. Ramirez
Publikováno v:
Bioengineering, Vol 11, Iss 3, p 200 (2024)
The neuroinflammatory cascade triggered by traumatic brain injury (TBI) represents a clinically important point for therapeutic intervention. Neuroinflammation generates oxidative stress in the form of high-energy reactive oxygen and nitrogen species
Externí odkaz:
https://doaj.org/article/fc46f6c9b1954fa8b6e78fbee33f10a7
Autor:
Laura T. Ferguson, Xiaonan Ma, Jacob W. Myerson, Jichuan Wu, Patrick M. Glassman, Marco E. Zamora, Elizabeth D. Hood, Michael Zaleski, Mengwen Shen, Eno-Obong Essien, Vladimir V. Shuvaev, Jacob S. Brenner
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 3, Pp n/a-n/a (2023)
Diseases of the pulmonary alveolus, such as pulmonary fibrosis, are leading causes of morbidity and mortality, but exceedingly few drugs are developed for them. A major reason for this gap is that after inhalation, drugs are quickly whisked away from
Externí odkaz:
https://doaj.org/article/eb489d494be74c0a89082fbe3a8a2bcc
Autor:
Ralph A. Pietrofesa, Kyewon Park, Om P. Mishra, Darrah Johnson-McDaniel, Jacob W. Myerson, Vladimir V. Shuvaev, Evguenia Arguiri, Shampa Chatterjee, Ganesh S. Moorthy, Athena Zuppa, Wei-Ting Hwang, Melpo Christofidou-Solomidou
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9477 (2021)
Metal-oxide nanoparticles (MO-NPs), such as the highly bioreactive copper-based nanoparticles (CuO-NPs), are widely used in manufacturing of hundreds of commercial products. Epidemiological studies correlated levels of nanoparticles in ambient air wi
Externí odkaz:
https://doaj.org/article/667c1e0c7db6464f8049489aad03fc9b
Autor:
Hamideh Parhiz, Jacob S. Brenner, Priyal N. Patel, Tyler E. Papp, Hamna Shahnawaz, Qin Li, Ruiqi Shi, Marco E. Zamora, Amir Yadegari, Oscar A. Marcos-Contreras, Ambika Natesan, Norbert Pardi, Vladimir V. Shuvaev, Raisa Kiseleva, Jacob W. Myerson, Thomas Uhler, Rachel S. Riley, Xuexiang Han, Michael J. Mitchell, Kieu Lam, James Heyes, Drew Weissman, Vladimir R. Muzykantov
Publikováno v:
Journal of Controlled Release
Current nucleoside-modified RNA lipid nanoparticle (modmRNA-LNP) technology has successfully paved the way for the highest clinical efficacy data from next-generation vaccinations against SARS-CoV-2 during the COVID-19 pandemic. However, such modmRNA
Autor:
Carla Riera-Domingo, Eduarda Leite-Gomes, Iris Charatsidou, Peihua Zhao, Giovanna Carrá, Federica Cappellesso, Larissa Mourao, Maxim De Schepper, Dana Liu, Jens Serneels, Mohamad-Gabriel Alameh, Vladimir V. Shuvaev, Tatjana Geukens, Edoardo Isnaldi, Hans Prenen, Drew Weissman, Vladimir R. Muzykantov, Stefaan Soenen, Christine Desmedt, Colinda L. G. J. Scheele, Anna Sablina, Mario Di Matteo, Rosa Martín-Pérez, Massimiliano Mazzone
Publikováno v:
Science Advances
Endothelial cells (ECs) grant access of disseminated cancer cells to distant organs. However, the molecular players regulating the activation of quiescent ECs at the premetastatic niche (PMN) remain elusive. Here, we find that ECs at the PMN coexpres
Autor:
Laura T. Ferguson, Elizabeth D. Hood, Tea Shuvaeva, Vladimir V. Shuvaev, Maria C. Basil, Zhicheng Wang, Jia Nong, Xiaonan Ma, Jichuan Wu, Jacob W. Myerson, Oscar A. Marcos-Contreras, Jeremy Katzen, Justine M. Carl, Edward E. Morrisey, Edward Cantu, Carlos H. Villa, Samir Mitragotri, Vladimir R. Muzykantov, Jacob S. Brenner
Publikováno v:
ACS Nano
A long-standing goal of nanomedicine is to improve a drug’s benefit by loading it into a nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers usually end up with only a small percentage of the injected dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27890969e38ca28d17e3ff872c3569de
https://europepmc.org/articles/PMC9339245/
https://europepmc.org/articles/PMC9339245/