Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vladimir Uzun"'
Autor:
Edyta E. Wojtowicz, Jayna J. Mistry, Vladimir Uzun, Charlotte Hellmich, Anita Scoones, Desmond W. Chin, Laura M. Kettyle, Francesca Grasso, Allegra M. Lord, David J. Wright, Graham J. Etherington, Petter S. Woll, Mirjam E. Belderbos, Kristian M. Bowles, Claus Nerlov, Wilfried Haerty, Leonid V. Bystrykh, Sten Eirik W. Jacobsen, Stuart A. Rushworth, Iain C. Macaulay
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-27 (2023)
Abstract Background Platelets and erythrocytes constitute over 95% of all hematopoietic stem cell output. However, the clonal dynamics of HSC contribution to these lineages remains largely unexplored. Results We use lentiviral genetic labeling of mou
Externí odkaz:
https://doaj.org/article/1e471c0563ff42f9a6e250e9ee8b4611
Autor:
Laura Mincarelli, Vladimir Uzun, David Wright, Anita Scoones, Stuart A. Rushworth, Wilfried Haerty, Iain C. Macaulay
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Single-cell approaches have revealed that the haematopoietic hierarchy is a continuum of differentiation, from stem cell to committed progenitor, marked by changes in gene expression. However, many of these approaches neglect isoform-level i
Externí odkaz:
https://doaj.org/article/0a5d14d83c0d45119b67eeb0035dc63b
Autor:
Edyta E. Wojtowicz, Jayna Mistry, Vladimir Uzun, Anita Scoones, Desmond W. Chin, Laura Kettyle, Francesca Grasso, Allegra M. Lord, Graham Etherington, Charlotte Hellmich, Petter S. Woll, Mirjam E. Belderbos, Kristian M. Bowles, Claus Nerlov, Wilfried Haerty, Leonid V. Bystrykh, Sten Eirik W. Jacobsen, Stuart A. Rushworth, Iain C. Macaulay
Anucleate cells - platelets and erythrocytes - constitute over 95% of all hematopoietic stem cell (HSC) output, but the clonal dynamics of HSC contribution to these lineages remains largely unexplored. Here, we use lentiviral RNA cellular barcoding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b66d81d1cc3a0523459be179185c19ca
https://doi.org/10.1101/2022.05.16.491933
https://doi.org/10.1101/2022.05.16.491933
Autor:
Wilfried Haerty, David Wright, Iain C. Macaulay, Laura Mincarelli, Stuart A. Rushworth, Vladimir Uzun
Single-cell approaches have revealed that the haematopoietic hierarchy is a continuum of differentiation, from stem cell to committed progenitor, marked by changes in gene expression. However, many of these approaches neglect isoform level informatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bbe4e7a82035dd18ab0cffe2eb484d5
https://doi.org/10.21203/rs.3.rs-151546/v1
https://doi.org/10.21203/rs.3.rs-151546/v1
Single-cell RNA sequencing (scRNA-seq) enables gene expression profiling and characterization of novel cell types within heterogeneous cell populations. However, most approaches cannot detect alternatively spliced transcripts, which can profoundly sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c017fc6e82f08046e0e8ff14986cf95
Autor:
edyta wojtowicz, Jayna Mistry, Vladimir Uzun, Anita Scoones, Desmond Chin, Laura Kettyle, Allegra Lord, Francesca Grasso, Graham Etherington, Charlotte Hellmich, Petter Woll, Mirjam Belderbos, Kristian Bowles, Leonid Bystrykh, Claus Nerlov, Wilfried Haerty, Sten Eirik Jacobsen, Stuart Rushworth, Iain Macaulay
Publikováno v:
Experimental Hematology. 111:S158
Autor:
Laura Mincarelli, Vladimir Uzun, Anita Scoones, Stuart Rushworth, Wilfred Haerty, Iain Macaulay
Publikováno v:
Experimental Hematology. 100:S89