Výsledky vyhledávání - "Vladimir Sobota"

Akademický článek

Analysis of drug-induced and spontaneous cardioversions reveals similar patterns leading to termination of atrial fibrillation

Autor: Arne van Hunnik, Vladimír Sobota, Stef Zeemering, Dragan Opacic, Billy Scaf, Elisa D’Alessandro, Karel Oyaert, Marion Kuiper, Jonas G. Diness, Ulrik S. Sørensen, James T. Milnes, Marcel A. G. van der Heyden, Thomas Jespersen, Ulrich Schotten, Sander Verheule

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

IntroductionThe mechanisms leading to the conversion of atrial fibrillation (AF) to sinus rhythm are poorly understood. This study describes the dynamic behavior of electrophysiological parameters and conduction patterns leading to spontaneous and ph

Externí odkaz: https://doaj.org/article/e2c1854f221946c0bbb48d1da7b3f23f

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Akademický článek

Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics

Autor: Delia I. Fernández, Sara Troitiño, Vladimír Sobota, Bibian M. E. Tullemans, Jinmi Zou, Helma van den Hurk, Ángel García, Saman Honarnejad, Marijke J. E. Kuijpers, Johan W. M. Heemskerk

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Distinct platelet activation patterns are elicited by the tyrosine kinase-linked collagen receptor glycoprotein VI (GPVI) and the G-protein coupled protease-activated receptors (PAR1/4) for thrombin. This is reflected in the different platel

Externí odkaz: https://doaj.org/article/e0e4cce4e1b944baa6e8d33649209870

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Monitoring of pulmonary embolism using electrical impedance tomography: A case study

Autor: Vladimir Sobota, Jan Suchomel

Publikováno v: 2013 E-Health and Bioengineering Conference (EHB).

Electrical impedance tomography (EIT) offers a non-invasive, radiation free, bedside alternative to conventional medical imaging systems. Studies have shown that monitoring of pulmonary perfusion or detection of pulmonary embolism (PE) could be a fie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00503c241431a96b8d1607921bb80bae
https://doi.org/10.1109/ehb.2013.6707415

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Akademický článek

The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats

Autor: Vladimír Sobota, Giulia Gatta, Arne van Hunnik, Iris van Tuijn, Marion Kuiper, James Milnes, Thomas Jespersen, Ulrich Schotten, Sander Verheule

Publikováno v: Frontiers in Pharmacology, Vol 11 (2021)

Aims: The acetylcholine-activated inward rectifier potassium current (IKACh) has been proposed as an atrial-selective target for the treatment of atrial fibrillation (AF). Using a novel selective IKACh inhibitor XAF-1407, the study investigates the e

Externí odkaz: https://doaj.org/article/5740d316d61a44a58ab71d78418199bc

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