Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vladimir Rait"'
Autor:
Esther H. Chang, Kathleen F. Pirollo, Will David William, Antonina Rait, Eugen Uhlmann, Vladimir Rait, Anush Peyman
Publikováno v:
Bioconjugate Chemistry. 11:153-160
Activation of the ras oncogene has been implicated in many types of human tumors. It has been shown that downmodulation of ras expression can lead to the reversion of the transformed phenotype of these tumor cells. Antisense oligodeoxyribonucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e7e2f8b491b9eeed5d52758a6eaa96
https://doi.org/10.1021/bc990106n
https://doi.org/10.1021/bc990106n
Autor:
Vladimir Rait, Barbara Ramsay Shaw
Publikováno v:
Antisense and Nucleic Acid Drug Development. 9:53-60
Modification of the phosphodiester linkages in DNA by replacing one of the nonbridging oxygens with borane, BH3, produces an isoelectronic mimic of DNA called boranophosphates. Nonstereoregular oligodeoxyribonucleoside all-boranophosphates are shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574f59419daaa34b321424e35157dfe9
https://doi.org/10.1089/oli.1.1999.9.53
https://doi.org/10.1089/oli.1.1999.9.53
Autor:
Dmitri S. Sergueev, Ken Porter, Barbara Ramsay Shaw, Kaizhang He, Zinaida A. Sergueeva, Jack S. Summers, Vladimir Rait
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6da5c623b9e78abcaeb5df9c803994d9
https://doi.org/10.1002/chin.200025286
https://doi.org/10.1002/chin.200025286
Autor:
Jing Wan, Zinaida A. Sergueeva, Jinlai Lin, Xin Wang, Mikhail I. Dobrikov, Ping Li, Barbara Ramsay Shaw, Dmitri S. Sergueev, Kaizhang He, Vladimir Rait
Publikováno v:
Annals of the New York Academy of Sciences. 1002
The P-boranophosphates are efficient and near perfect mimics of natural nucleic acids in permitting reading and writing of genetic information with high yield and accuracy. Substitution of a borane (-BH3) group for oxygen in the phosphate ester bond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b841e09e52f6cf65571cb43f8dc4267e
https://pubmed.ncbi.nlm.nih.gov/14751819
https://pubmed.ncbi.nlm.nih.gov/14751819
Autor:
Vladimir Rait, Mikhail I. Dobrikov, Zinaida A. Sergueeva, Dmitri S. Sergueev, Jing Wan, Barbara Ramsay Shaw, Kaizhang He, Xin Wang, Jinlai Lin, Kenneth W. Porter
Publikováno v:
Collection Symposium Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71ba6d983c5f954249867b8cdd4daf0
https://doi.org/10.1135/css200205169
https://doi.org/10.1135/css200205169
Autor:
Kathleen F. Pirollo, Jeffrey E Krygier, Lai-Man Xiang, Esther H. Chang, Antonina Rait, Vladimir Rait
Publikováno v:
Cancer gene therapy. 8(10)
Poor response to chemotherapy in patients with breast cancer is often associated with overexpression of HER-2/ neu. Interference with HER-2 mRNA translation by means of antisense oligonucleotides might improve the efficacy of chemotherapy. To test th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6c933726207959652b690000a65523
https://pubmed.ncbi.nlm.nih.gov/11687896
https://pubmed.ncbi.nlm.nih.gov/11687896
Autor:
Kaizhang He, Zinaida A. Sergueeva, Vladimir Rait, Jack S. Summers, Dmitri S. Sergueev, Ken Porter, Barbara Ramsay Shaw
Nucleoside boranophosphates are distinctive in that one of the non-bridging oxygens in the phosphate diester 1 is replaced by a borane moiety (BH3). Although they retain the same net charge, BH3(-)-ODN have unique chemical and biochemical characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87114ec1924089fe577c28ecd90efe25
https://doi.org/10.1016/s0076-6879(00)13015-0
https://doi.org/10.1016/s0076-6879(00)13015-0
Autor:
Kaizhang He, Vladimir Rait, Jack S. Summers, Bozenna Krzyzanowska, Faqing Huang, Dmitri S. Sergueev, Barbara Ramsay Shaw
Publikováno v:
Nucleosidesnucleotides. 18(6-7)
Important chemical and biochemical properties of boranophosphate DNA and RNA oligonucleotides are reviewed. Stereoregular boranophosphate oligomers can be synthesized enzymatically and form stable duplexes with DNA. Fully boronated, non-stereoregular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e2700db9b447e805031ba17b95716a
https://pubmed.ncbi.nlm.nih.gov/10474223
https://pubmed.ncbi.nlm.nih.gov/10474223
Autor:
Vladimir Rait, Brenda Dickow, Wei Chen, John W. Gillespie, Peter Tunon, Ulka N. Vaishampayan, Daryn Smith, Seema Sethi, Alexandrine Derrien-Colemyn
Publikováno v:
Journal of Clinical Oncology. 31:382-382
382 Background: Although a number of prognostic biomarkers have been explored in advanced renal cancer, to date none have been useful in therapeutic outcome prediction. Methods: Following regulatory approval, formalin-fixed paraffin embedded pre-ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5da98bf4c45f7d1e6088bf71c410cb
https://doi.org/10.1200/jco.2013.31.6_suppl.382
https://doi.org/10.1200/jco.2013.31.6_suppl.382