Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vladimir Purvanov"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chemokine-guided leukocyte migration is a hallmark of the immune system to cope with invading pathogens. Intruder confronted dendritic cells (DCs) induce the expression of the chemokine receptor CCR7, which enables them to sense and migrate along che
Externí odkaz:
https://doaj.org/article/d91e8a70e3574cf0af38cf3a56de418f
Autor:
Edith Uetz-von Allmen, Guerric P. B. Samson, Vladimir Purvanov, Takahiro Maeda, Daniel F. Legler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dendritic cells (DCs) are potent and versatile professional antigen-presenting cells and central for the induction of adaptive immunity. The ability to migrate and transport peripherally acquired antigens to draining lymph nodes for subsequent cognat
Externí odkaz:
https://doaj.org/article/a08ddc28f69949bb87c24a2c683984fe
Autor:
Julia M. Laufer, Mark A. Hauser, Ilona Kindinger, Vladimir Purvanov, Andreas Pauli, Daniel F. Legler
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 995-1009.e6 (2019)
Summary: Chemokine-guided cell migration is pivotal for many immunological and developmental processes. How chemokine receptor signaling persists to guarantee sustained directional migration despite receptor desensitization and internalization remain
Externí odkaz:
https://doaj.org/article/ea564785a5f1495bbbce98a339b5567a
Autor:
Barbara D. Jakobs, Lisa Spannagel, Vladimir Purvanov, Edith Uetz-von Allmen, Christoph Matti, Daniel F. Legler
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2597 (2019)
The chemokine receptor CCR7 plays a pivotal role in health and disease. In particular, CCR7 controls homing of antigen-bearing dendritic cells and T cells to lymph nodes, where adaptive immune responses are initiated. However, CCR7 also guides T cell
Externí odkaz:
https://doaj.org/article/9490b0b1526c4c1f9e1e7bca6c8539db
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3876 (2018)
Chemokines are essential guidance cues orchestrating cell migration in health and disease. Cognate chemokine receptors sense chemokine gradients over short distances to coordinate directional cell locomotion. The chemokines CCL19 and CCL21 are essent
Externí odkaz:
https://doaj.org/article/3b3090c3db654ed8b43ba141ec284a00
Publikováno v:
eLife, Vol 3 (2014)
Homotypic or entotic cell-in-cell invasion is an integrin-independent process observed in carcinoma cells exposed during conditions of low adhesion such as in exudates of malignant disease. Although active cell-in-cell invasion depends on RhoA and ac
Externí odkaz:
https://doaj.org/article/ce6e78f004ed48048729c7c068fadc0f
Autor:
Graham Anderson, Vladimir Purvanov, Sonia M. Parnell, Andrea J. White, William E. Jenkinson, Yousuke Takahama, Kieran D. James, Daniel F. Legler, Izumi Ohigashi
Publikováno v:
Blood Adv
The release of newly selected αβT cells from the thymus is key in establishing a functional adaptive immune system. Emigration of the first cohorts of αβT cells produced during the neonatal period is of particular importance, because it initiates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ef8ff18ea4f71e083d40be053aeb55
https://europepmc.org/articles/PMC7805325/
https://europepmc.org/articles/PMC7805325/
Autor:
Vladimir Purvanov, Christoph Matti, Barbara D. Jakobs, Julia M. Laufer, Edith Uetz-von Allmen, Daniel F. Legler, Marcus Thelen
Publikováno v:
Molecular Pharmacology. 91:331-338
Chemokine receptors are seven transmembrane-domain receptors belonging to class A of G-protein-coupled receptors (GPCRs). The receptors together with their chemokine ligands constitute the chemokine system, which is essential for directing cell migra
Autor:
Julia M, Laufer, Mark A, Hauser, Ilona, Kindinger, Vladimir, Purvanov, Andreas, Pauli, Daniel F, Legler
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 995-1009.e6 (2019)
Summary: Chemokine-guided cell migration is pivotal for many immunological and developmental processes. How chemokine receptor signaling persists to guarantee sustained directional migration despite receptor desensitization and internalization remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::909079edfc0f6b91c57012c50b050d33
Autor:
Paul J, Collins, Michelle L, McCully, Laura, Martínez-Muñoz, César, Santiago, James, Wheeldon, Stephan, Caucheteux, Sylvia, Thelen, Valentina, Cecchinato, Julia M, Laufer, Vladimir, Purvanov, Yoan R, Monneau, Hugues, Lortat-Jacob, Daniel F, Legler, Mariagrazia, Uguccioni, Marcus, Thelen, Vincent, Piguet, Mario, Mellado, Bernhard, Moser
Publikováno v:
The FASEB Journal
The chemokine receptor, CXC chemokine receptor 4 (CXCR4), is selective for CXC chemokine ligand 12 (CXCL12), is broadly expressed in blood and tissue cells, and is essential during embryogenesis and hematopoiesis. CXCL14 is a homeostatic chemokine wi