Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Vladimir Ponomarev"'
Publikováno v:
Известия Иркутского государственного университета: Серия "Математика", Vol 39, Iss 1, Pp 17-33 (2022)
In the paper, the stochastic method of global extremum search is discussed, modified and tested. The method is based on normal distribution modeling and provides covariance matrix adaptation. The method is iterative; a genetic algorithm has been deve
Externí odkaz:
https://doaj.org/article/ef7bc534df77470bb1c4f8d2284a650a
Autor:
Matthew S. Skovgard, Hocine R. Hocine, Jasmeen K. Saini, Maxim Moroz, Rebecca Y. Bellis, Srijita Banerjee, Aurore Morello, Vladimir Ponomarev, Jonathan Villena-Vargas, Prasad S. Adusumilli
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 355-367 (2021)
Summary: Success in solid tumor chimeric antigen receptor (CAR) T-cell therapy requires overcoming several barriers, including lung sequestration, inefficient accumulation within the tumor, and target-antigen heterogeneity. Understanding CAR T-cell k
Externí odkaz:
https://doaj.org/article/531742c1967d44c29efecf21b9ef396b
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Cellular immunotherapies have emerged as a successful therapeutic approach to fight a wide range of human diseases, including cancer. However, responses are limited to few patients and tumor types. An in-depth understanding of the complexity and dyna
Externí odkaz:
https://doaj.org/article/3255496848514f59a5af9c0b5b90d333
Autor:
Maxim A. Moroz, Juan Zurita, Anna Moroz, Ekaterina Nikolov, Yury Likar, Konstantin Dobrenkov, Jason Lee, Larissa Shenker, Ronald Blasberg, Inna Serganova, Vladimir Ponomarev
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss , Pp 15-22 (2021)
Bioluminescence reporter gene imaging is a robust, high-throughput imaging modality that is useful for tracking cells and monitoring biological processes, both in cell culture and in small animals. We introduced and characterized a novel bioluminesce
Externí odkaz:
https://doaj.org/article/b271fee7bdc745d58af2772e2da2b5ec
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 447-458 (2021)
Several types of gene- and cell-based therapeutics are now emerging in the cancer immunotherapy, transplantation, and regenerative medicine landscapes. Radionuclear-based imaging can be used as a molecular imaging tool for repetitive and non-invasive
Externí odkaz:
https://doaj.org/article/b17ef43a05554527b97d4ce690ab9e5f
Autor:
Mayuresh M. Mane, Ivan J. Cohen, Ellen Ackerstaff, Khalid Shalaby, Jenny N. Ijoma, Myat Ko, Masatomo Maeda, Avi S. Albeg, Kiranmayi Vemuri, Jaya Satagopan, Anna Moroz, Juan Zurita, Larissa Shenker, Masahiro Shindo, Tanner Nickles, Ekaterina Nikolov, Maxim A. Moroz, Jason A. Koutcher, Inna Serganova, Vladimir Ponomarev, Ronald G. Blasberg
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 382-395 (2020)
To enhance human prostate-specific membrane antigen (hPSMA)-specific chimeric antigen receptor (CAR) T cell therapy in a hPSMA+ MyC-CaP tumor model, we studied and imaged the effect of lactate dehydrogenase A (LDH-A) depletion on the tumor microenvir
Externí odkaz:
https://doaj.org/article/26eebb7cb3524556b2f6f1fc9d9dda83
Publikováno v:
Water, Vol 15, Iss 4, p 821 (2023)
Dissolved methane coming from its various sources is an important component of seawater. Finding these probable sources allows for the determination of potential oil and/or gas deposit areas. From an ecological point of view, methane transport studie
Externí odkaz:
https://doaj.org/article/505a1d56a35b41a9b8d6c8451bac2618
Autor:
Inna Serganova, Ekaterina Moroz, Ivan Cohen, Maxim Moroz, Mayuresh Mane, Juan Zurita, Larissa Shenker, Vladimir Ponomarev, Ronald Blasberg
Publikováno v:
Molecular Therapy: Oncolytics, Vol 4, Iss C, Pp 41-54 (2017)
Chimeric antigen receptor (CAR) T cell therapy in hematologic malignancies has shown remarkable responses, but the same level of success has not been observed in solid tumors. A new prostate cancer model (Myc-CaP:PSMA(+)) and a second-generation anti
Externí odkaz:
https://doaj.org/article/2b20dfb75b604b0189594895854c5ca0
Autor:
Vladimir Ponomarev, Michael Doubrovin, Inna Serganova, Tatiana Beresten, Jelena Vider, Aleksander Shavrin, Ludmila Ageyeva, Julius Balatoni, Ronald Blasberg, Juri Gelovani Tjuvajev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 245-254 (2003)
To optimize the sensitivity of imaging HSV1-tk/GFP reporter gene expression, a series of HSV1-tk/GFP mutants was developed with altered nuclear localization and better cellular enzymatic activity, compared to that of the native HSV1-tk/GFP fusion pro
Externí odkaz:
https://doaj.org/article/6942fa4e9c8044e586c1d5dbec090c88
Autor:
Vladimir Ponomarev, Michael Doubrovin, Clay Lyddane, Tatiana Beresten, Julius Balatoni, William Bornman, Ronald Finn, Timothy Akhurst, Steven Larson, Ronald Blasberg, Michel Sadelain, Juri Gelovani Tjuvajev
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 6, Pp 480-488 (2001)
A noninvasive method for molecular imaging of T-cell activity in vivo would be of considerable value. It would aid in understanding the role of specific genes and signal transduction pathways in the course of normal and pathologic immune responses, c
Externí odkaz:
https://doaj.org/article/7041a0c094e34993ba84cd45c0f9875e