Zobrazeno 1 - 10
of 658
pro vyhledávání: '"Vladimir P. Torchilin"'
Autor:
Yasamin Davatgaran Taghipour, Amir Zarebkohan, Roya Salehi, Mehdi Talebi, Reza Rahbarghazi, Monireh Khordadmehr, Sharareh Khavandkari, Fahimeh Badparvar, Vladimir P. Torchilin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Effective targeting and delivery of large amounts of medications into the cancer cells enhance their therapeutic efficacy through saturation of cellular defensive mechanisms, which is the most privilege of nano drug delivery systems (NDDS) c
Externí odkaz:
https://doaj.org/article/9b3e95f12ac441c1807d78d4ea5050da
Autor:
Md Abdus Subhan, Vladimir P. Torchilin
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 830 (2024)
Among breast cancers, triple-negative breast cancer (TNBC) has been recognized as the most aggressive type with a poor prognosis and low survival rate. Targeted therapy for TNBC is challenging because it lacks estrogen receptor (ER), progesterone rec
Externí odkaz:
https://doaj.org/article/8435a3aedc014d3783f384e946b036f8
Autor:
Marwan Moussa, Md. Raihan Chowdhury, David Mwin, Mohamed Fatih, Gokul Selveraj, Ahmed Abdelmonem, Mohamed Farghaly, Qianhui Dou, Nina Filipczak, Tatyana Levchenko, Vladimir P. Torchilin, Vassiliki Boussiotis, S. Nahum Goldberg, Muneeb Ahmed
Publikováno v:
PLoS ONE, Vol 18, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/6ff4eb9568d845f2b367c5c7d97342a5
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 970 (2023)
Breast cancer is the most frequently diagnosed cancer among women. Breast cancer is also the key reason for worldwide cancer-related deaths among women. The application of small interfering RNA (siRNA)-based drugs to combat breast cancer requires eff
Externí odkaz:
https://doaj.org/article/29a9c0f134a24ba2b37941401fc340fa
Autor:
Md Abdus Subhan, Vladimir P. Torchilin
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1242 (2023)
Antibody–drug conjugates (ADCs) are a potential and promising therapy for a wide variety of cancers, including breast cancer. ADC-based drugs represent a rapidly growing field of breast cancer therapy. Various ADC drug therapies have progressed ove
Externí odkaz:
https://doaj.org/article/0c05546b926845e590b5b4d0f27f2e49
Autor:
Janaína Artem Ataide, Julia Cedran Coco, Érica Mendes dos Santos, Viviane Beraldo-Araujo, Jéssica Ribeiro Alves Silva, Karine Cappuccio de Castro, André Moreni Lopes, Nina Filipczak, Satya Siva Kishan Yalamarty, Vladimir P. Torchilin, Priscila Gava Mazzola
Publikováno v:
Molecules, Vol 28, Iss 3, p 1449 (2023)
Achieving the best possible outcome for the therapy is the main goal of a medicine. Therefore, nanocarriers and co-delivery strategies were invented to meet this need, as they can benefit many diseases. This approach was applied specifically for canc
Externí odkaz:
https://doaj.org/article/9b4445aabf404f40a0a914b4598f267f
Autor:
Md Abdus Subhan, Vladimir P. Torchilin
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 153 (2023)
Nanobiopolymers such as chitosan, gelatin, hyaluronic acid, polyglutamic acid, lipids, peptides, exosomes, etc., delivery systems have prospects to help overwhelmed physiological difficulties allied with the delivery of siRNA drugs to solid tumors, i
Externí odkaz:
https://doaj.org/article/a7f5972dcdc643fab0b807f1763de4a8
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 443-458 (2019)
Modification of nanoparticle surfaces with PEG has been widely considered the gold standard for many years. However, PEGylation presents controversial and serious challenges including lack of functionality, hindered cellular interaction, allergic rea
Externí odkaz:
https://doaj.org/article/19da2ba7dd1c4590b79c694b2074acfb
Autor:
Nino Zavradashvili, Can Sarisozen, Giorgi Titvinidze, Giuli Otinashvili, Tengiz Kantaria, Davit Tugushi, Jordi Puiggali, Vladimir P. Torchilin, Ramaz Katsarava
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 2090-2101 (2019)
Externí odkaz:
https://doaj.org/article/2f42c8dd389f45c39b54160e40414df7
Autor:
Satya Siva Kishan Yalamarty, Nina Filipczak, Xiang Li, Tanvi Vinod Pathrikar, Colin Cotter, Vladimir P. Torchilin
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1470 (2022)
Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance
Externí odkaz:
https://doaj.org/article/4e370d251b6c41c5a7ae911383402504