Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vladimir P. Grinevich"'
Autor:
Vsevolod V. Nemets, Ekaterina P. Vinogradova, Vladislav Zavialov, Vladimir P. Grinevich, Evgeny A. Budygin, Raul R. Gainetdinov
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1280 (2024)
There is a gap in existing knowledge of stress-triggered neurochemical and behavioral adaptations in females. This study was designed to explore the short-term consequences of a single social defeat (SD) on accumbal dopamine (DA) dynamics and related
Externí odkaz:
https://doaj.org/article/45507862d5554f46a5f0581f5a9d67a2
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Using a variety of animal models that simulate key features of the alcohol use disorder (AUD), remarkable progress has been made in identifying neurochemical targets that may contribute to the development of alcohol addiction. In this search, the dop
Externí odkaz:
https://doaj.org/article/bc7a23b611e14af8aa8b93c79662667a
Autor:
Vsevolod V. Nemets, Alex L. Deal, Vladislav E. Sobolev, Vladimir P. Grinevich, Raul R. Gainetdinov, Evgeny A. Budygin
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 35 (2022)
The present study aimed to explore the consequences of a single exposure to a social defeat on dopamine release in the rat nucleus accumbens measured with a fast-scan cyclic voltammetry. We found that 24 h after a social defeat, accumbal dopamine res
Externí odkaz:
https://doaj.org/article/1e48d3b062c14453934d969a75389821
Autor:
Vladimir P. Grinevich, Amir N. Zakirov, Uliana V. Berseneva, Elena V. Gerasimova, Raul R. Gainetdinov, Evgeny A. Budygin
Publikováno v:
Cells, Vol 11, Iss 9, p 1533 (2022)
Progress in the development of technologies for the real-time monitoring of neurotransmitter dynamics has provided researchers with effective tools for the exploration of etiology and molecular mechanisms of neuropsychiatric disorders. One of these p
Externí odkaz:
https://doaj.org/article/58d8499c930844c3bf59ce235a81db7c
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Background The purpose of this study was to develop a positron emission tomography (PET) imaging probe that is easy to synthesize and selectively targets melanoma in vivo. Herein, we report the synthesis and preclinical evaluation of N-(2-di
Externí odkaz:
https://doaj.org/article/deb9567d297a473e939851f90055ef79
Autor:
Konstantin N Zabegalov, Fabiano Costa, Yuliya A Viktorova, Gleb O Maslov, Tatiana O Kolesnikova, Elena V Gerasimova, Vladimir P Grinevich, Evgeny A Budygin, Allan V Kalueff
Publikováno v:
Journal of Psychopharmacology. :026988112311664
Background: The dopamine transporter (DAT) is the main regulator of dopamine concentration in the extrasynaptic space. The pharmacological inhibition of the DAT results in a wide spectrum of behavioral manifestations, which have been identified so fa
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-11 (2017)
EJNMMI Research
EJNMMI Research
Background The purpose of this study was to develop a positron emission tomography (PET) imaging probe that is easy to synthesize and selectively targets melanoma in vivo. Herein, we report the synthesis and preclinical evaluation of N-(2-diethylamin
Autor:
Merouane Bencherif, Vladimir P. Grinevich, Reinoud Maex, Evgeny A. Budygin, Boris Gutkin, Valentina P. Grinevich
Publikováno v:
ACS Chemical Neuroscience
Neuronal nicotinic acetylcholine receptors (NNRs) of the α7 subtype have been shown to contribute to the release of dopamine in the nucleus accumbens. The site of action and the underlying mechanism, however, are unclear. Here we applied a circuit m
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4842-4847
Compounds containing a quinuclidine scaffold are promising drug candidates for pharmacological management of the central nervous system (CNS) pathologies implicating nAChRs. We have carried out binding affinity and in-silico docking studies of arylme
Autor:
Daniel Yohannes, S. Rao Akireddy, Vladimir P. Grinevich, David C. Kombo, Dawn N. Hooker, Terry Hauser, Christopher D. Hepler, Douglas Mountfort, Sharon R. Letchworth, Jiahui Zhang, Melanie N. Kiser, Andrew I. Selwood
Publikováno v:
Neuropharmacology. 62:2239-2250
The interaction of 13-desmethylspirolide C (SPX-desMe-C) and gymnodimine with several nicotinic and muscarinic acetylcholine receptors was investigated. Interaction at the muscarinic receptors was minimal. At nicotinic receptors, both SPX-desMe-C and