Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Vladimir P, Skulachev"'
Autor:
Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Boris V. Chernyak, Armen Y. Mulkidjanian, Maxim V. Skulachev, Gregory A. Shilovsky, Konstantin G. Lyamzaev, Vitaliy B. Borisov, Fedor F. Severin, Victor A. Sadovnichii
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12540 (2023)
Cellular respiration is associated with at least six distinct but intertwined biological functions. (1) biosynthesis of ATP from ADP and inorganic phosphate, (2) consumption of respiratory substrates, (3) support of membrane transport, (4) conversion
Externí odkaz:
https://doaj.org/article/e0c1fa324f424ca8a9e70842da931f30
Autor:
Susanne Holtze, Ekaterina Gorshkova, Stan Braude, Alessandro Cellerino, Philip Dammann, Thomas B. Hildebrandt, Andreas Hoeflich, Steve Hoffmann, Philipp Koch, Eva Terzibasi Tozzini, Maxim Skulachev, Vladimir P. Skulachev, Arne Sahm
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Most research on mechanisms of aging is being conducted in a very limited number of classical model species, i.e., laboratory mouse (Mus musculus), rat (Rattus norvegicus domestica), the common fruit fly (Drosophila melanogaster) and roundworm (Caeno
Externí odkaz:
https://doaj.org/article/6ee18a652b7f4283a8c8e75e4184a1c3
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 1965 (2022)
As inhabitants of soda lakes, Thioalkalivibrio versutus are halo- and alkaliphilic bacteria that have previously been shown to respire with the first demonstrated Na+-translocating cytochrome-c oxidase (CO). The enzyme generates a sodium-motive force
Externí odkaz:
https://doaj.org/article/107f5ac246284a8fba72f31d79642fea
Autor:
Pavel A. Nazarov, Ilya A. Osterman, Artem V. Tokarchuk, Marina V. Karakozova, Galina A. Korshunova, Konstantin G. Lyamzaev, Maxim V. Skulachev, Elena A. Kotova, Vladimir P. Skulachev, Yuri N. Antonenko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mitochondria-targeted antioxidants are known to alleviate mitochondrial oxidative damage that is associated with a variety of diseases. Here, we showed that SkQ1, a decyltriphenyl phosphonium cation conjugated to a quinone moiety, exhibited
Externí odkaz:
https://doaj.org/article/15da0121ba4a44c098f410443074d542
Autor:
Chupalav M. Eldarov, Lora E. Bakeeva, Thomas B. Hildebrandt, Susanne Holtze, Vladimir P. Skulachev, Irina M. Vangely, V. B. Vays
Publikováno v:
Aging (Albany NY)
Aging, 13(22):24524-24541
Aging, 13(22):24524-24541
The authors examined the ultrastructure of mitochondrial apparatus of skeletal muscles of naked mole rats (Heterocephalus glaber) from the age of 6 months to 11 years. The obtained results have demonstrated that the mitochondria in skeletal muscles o
Autor:
Chupalav M. Eldarov, Irina M. Vangely, Valeriya B. Vays, Eugene V. Sheval, Susanne Holtze, Thomas B. Hildebrandt, Natalia G. Kolosova, Vasily A. Popkov, Egor Y. Plotnikov, Dmitry B. Zorov, Lora E. Bakeeva, Vladimir P. Skulachev
Publikováno v:
Cells, Vol 9, Iss 3, p 712 (2020)
Electron microscopic study of cardiomyocytes taken from healthy Wistar and OXYS rats and naked mole rats (Heterocephalus glaber) revealed mitochondria in nuclei that lacked part of the nuclear envelope. The direct interaction of mitochondria with nuc
Externí odkaz:
https://doaj.org/article/6d470851b08e4f2e9eb1de28ea8bcf3c
Autor:
Denis N. Silachev, Egor Y. Plotnikov, Ljubava D. Zorova, Irina B. Pevzner, Natalia V. Sumbatyan, Galina A. Korshunova, Mikhail V. Gulyaev, Yury A. Pirogov, Vladimir P. Skulachev, Dmitry B. Zorov
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 14487-14503 (2015)
We explored the neuroprotective properties of natural plant-derived antioxidants plastoquinone and thymoquinone (2-demethylplastoquinone derivative) modified to be specifically accumulated in mitochondria. The modification was performed through chemi
Externí odkaz:
https://doaj.org/article/f8a7d86faa9a4f91b58f4b66e549e72b
Autor:
V.V. Ashapkin, G. V. Morgunova, T S Putyatina, Vladimir P. Skulachev, G. A. Shilovsky, A. V. Seliverstov, Alexander V. Markov, E.V. Sorokina
Publikováno v:
Biochemistry. Biokhimiia
This review discusses genetic and molecular pathways that link circadian timing with metabolism, resulting in the emergence of positive and negative regulatory feedback loops. The Nrf2 pathway is believed to be a component of the anti-aging program r
Autor:
Egor Y. Plotnikov, Irina B. Pevzner, Ljubava D. Zorova, Valery P. Chernikov, Andrey N. Prusov, Igor I. Kireev, Denis N. Silachev, Vladimir P. Skulachev, Dmitry B. Zorov
Publikováno v:
Antioxidants, Vol 8, Iss 6, p 176 (2019)
Induced and frequently unwanted alterations in the mitochondrial structure and functions are a key component of the pathological cascade in many kidney pathologies, including those associated with acute damage. One of the principal pathogenic element
Externí odkaz:
https://doaj.org/article/ab09a3f81da04e9e8518a5d63ae6aa57
Autor:
T S Putyatina, Vladimir P. Skulachev, Maxim V. Skulachev, G. A. Shilovsky, Nikita A Popov, Victor Antonovich Sadovnichii, Alexander V. Markov
Publikováno v:
Aging. 12:5566-5584
Homo sapiens and naked mole rats (Heterocephalus glaber) are vivid examples of social mammals that differ from their relatives in particular by an increased lifespan and a large number of neotenic features. An important fact for biogerontology is tha