Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Vladimir N Minin"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1007999 (2020)
Birth-death processes have given biologists a model-based framework to answer questions about changes in the birth and death rates of lineages in a phylogenetic tree. Therefore birth-death models are central to macroevolutionary as well as phylodynam
Externí odkaz:
https://doaj.org/article/b770297fedaf422b802d07874743ab5d
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1007774 (2020)
Coalescent theory combined with statistical modeling allows us to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. When sequences are sampled serially through time and the
Externí odkaz:
https://doaj.org/article/a12e8166102741dfb75db7e805a95615
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1008030 (2020)
The human body generates a diverse set of high affinity antibodies, the soluble form of B cell receptors (BCRs), that bind to and neutralize invading pathogens. The natural development of BCRs must be understood in order to design vaccines for highly
Externí odkaz:
https://doaj.org/article/b8b464fde53b4a1ba513628dc21726dd
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 10, p e1006388 (2018)
B cells develop high affinity receptors during the course of affinity maturation, a cyclic process of mutation and selection. At the end of affinity maturation, a number of cells sharing the same ancestor (i.e. in the same "clonal family") are releas
Externí odkaz:
https://doaj.org/article/81bd538e6bad475499757b4572e3e6d0
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 3, p e1004789 (2016)
Phylodynamics seeks to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. One way to accomplish this task formulates an observed sequence data likelihood exploiting a coalesc
Externí odkaz:
https://doaj.org/article/9d01366323b64482b46a413698afd00a
Autor:
Chelsea R. Baker, Ivan Barilar, Leonardo S. de Araujo, Anne W. Rimoin, Daniel M. Parker, Rosanna Boyd, James L. Tobias, Patrick K. Moonan, Eleanor S. Click, Alyssa Finlay, John E. Oeltmann, Vladimir N. Minin, Chawangwa Modongo, Nicola M. Zetola, Stefan Niemann, Sanghyuk S. Shin
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 5, Pp 977-987 (2023)
Combining genomic and geospatial data can be useful for understanding Mycobacterium tuberculosis transmission in high-burden tuberculosis (TB) settings. We performed whole-genome sequencing on M. tuberculosis DNA extracted from sputum cultures from a
Externí odkaz:
https://doaj.org/article/4d741a4e927a49c6a8443c138fc4b25d
Publikováno v:
Ann Appl Stat
The annals of applied statistics, vol 17, iss 1
The annals of applied statistics, vol 17, iss 1
Phylodynamics is a set of population genetics tools that aim at reconstructing demographic history of a population based on molecular sequences of individuals sampled from the population of interest. One important task in phylodynamics is to estimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6e3430e66bf4542b0335d1ce65be60
https://europepmc.org/articles/PMC10237588/
https://europepmc.org/articles/PMC10237588/
Publikováno v:
ArXiv
Branching process inspired models are widely used to estimate the effective reproduction number -- a useful summary statistic describing an infectious disease outbreak -- using counts of new cases. Case data is a real-time indicator of changes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f076df69323cc37e9d5955ffec9adfdb
https://pubmed.ncbi.nlm.nih.gov/35979401
https://pubmed.ncbi.nlm.nih.gov/35979401
Autor:
Chelsea R. Baker, Ivan Barilar, Leonardo S. de Araujo, Anne W. Rimoin, Daniel M. Parker, Rosanna Boyd, James L. Tobias, Patrick K. Moonan, Eleanor S. Click, Alyssa Finlay, John E. Oeltmann, Vladimir N. Minin, Chawangwa Modongo, Nicola M. Zetola, Stefan Niemann, Sanghyuk S. Shin
IntroductionCombining genomic and geospatial data can be useful for understanding Mycobacterium tuberculosis (Mtb) transmission in high tuberculosis burden settings.MethodsWe performed whole genome sequencing (WGS) on Mtb DNA extracted from sputum cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca06c8b06e5ee111ec6fd775be4ef22c
https://doi.org/10.1101/2022.04.13.22273731
https://doi.org/10.1101/2022.04.13.22273731
Publikováno v:
PeerJ, Vol 2, p e373 (2014)
We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC). This estimation is non-trivial, as the data consist of ordinal measure
Externí odkaz:
https://doaj.org/article/f75d470afa5a4c14aac5b2e81b635709